can dsyphraxia be linked with muscular dystrophy duchenne?
544481
That's a very interesting question, especially considering that muscular dystrophy mainly affects boys, and dyspraxia is more common in males, as well as them both involving muscular dysfunction... I've done a quick literature search (pubmed, medline), which revealed nothing about a possible link. They do appear to have separate etiological and biological origins though, with dyspraxia likely being a dysfunction of neural connections, while DMD is more of a killing/atrophy of muscle fibres, i.e. dyspraxia is a brain dysfunction, DMD a muscular dysfunction. This does not exclude the possibility of a relationship however, and it may be of interest to researchers in the field of movement disorders... \n\nAll the best, hope that helps somewhat!
28307
I think it is possible thats how it came about .... Just as jeans are passed to an unborn child from a father so can a dvirus .... I had raised the question to a OB Doc. when I was attending the visits for my son before he was born and thats what she told me.... Hope I could help
260970
Yes, it is XYY and it is uncommon.  However, if you have this abnormality, you are unlikely to ever know it.  The tendency to violence with this abnormality is largely discredited, most evidence shows no abnormal tendencies in these people.  See the website below for more information and read the special chapter in the referenced book for an even more fascinating analysis of this question.\n\nEdit:\nI have looked into it a bit more and have found that the name of the condition is Jacobs Syndrome.  As to the question about whether it is possible, it certainly is possible.  It happens during meiosis II, when there is nondisjunction of sister chromatids of the Y chromosome, resulting in both sister chromatids in one cell and none in the other cell.  Nondisjunction means that the chromatids are normally supposed to split apart, one going into each cell, but that doesn't happen.
399075
Yes.\n\nBoth colour blindness and hemophilia are X-linked, and recessive. This means that if you are male, you will have the trait (because you only have 1 X chromosome), but if you are female, you have to have the disease on both your X chromosomes.\n\nThe 'normal healthy woman' had to get a hemophilia-X from her father (since he only has 1 X) - call it X(h) - and he was *not* colourblind so the X(h) doesn't carry the colourblindness mutation.\n\nShe also *had* to get a colour-blind-X from her mother, since her mother has to have 2 copies in order to *be* colourblind - call it X(b). So, she is X(h) X(b).\n\nShe marries a colourblind but not hemophiliac man: he must be X(b)Y. No other option.\n\nThere are thus four different possible outcomes for their children:\n\nX(b) X(h) mates with X(b)Y:\n\nX(b) X(b) - colour blind daughter\nX(b) Y - colour blind son\nX(h) X(b) - normal daughter (but carries both recessive traits)\nX(h) Y - hemophiliac son\n\nHope that was clear enough! :)
86457
This is not an exact information. HTLV type II  has been associated with several cases of myelopathy/tropical spastic paraparesis (HAM/TSP)-like neurological disease, which can be mistaken for MS.
805272
Yeah, you should see the rheumatologist.  The previous poster is right, the creatine kinase (CK or CPK) tends to go up when patients are on cholesterol medicines, or right after heavy exercise.  That being said, an elevation of CK in the setting of fatigue (like you're describing) makes me worry about myositis, usually an autoimmune problem.  see the rheumatologist (the autoimmune specialist), and they'll work it up further.  Like the prev poster said, it could be hypothyroidism, but I'd doubt it.  It's not malignant hyperthermia or neuroleptic malignant syndrome, I'll guarantee you that.
453082
It can happen to anybody - check with your doctor to find out if yours is hemophilia.  There are other blood disorders as well, such as sickle-cell anemia.  That's a disorder where the red bood cells change shape and can't carry oxygen as well as they should be able to.\n\nsoaplady99ca is incorrect in saying that it only effects men.  If the father of a child has the trait, and the mother of a child is a carrier, and the mother passes the chromosome with the trait, then a female can get it - X(defect)X(defect) would result in a female with the defect.
992956
between the dys and the ctional
817234
Degenerative - Alzheimer's disease\nToxic - Strychnine Poisoning\nVascular - Atherosclerotic heart disease\nCancerous - Pancreatic cancer\nEpileptic - electrical disorder of the brain\nHereditary - Tay Sachs disease\nInflammatory - Rheumatoid Arthritis\nDeficiency - Pernicious anemia - deficiency of vitamin B12\nPsychiatric - Schzophrenia\nCongenital - Pyloric stenosis, food can't get into the stomach due to a block
468270
Duchenne’s Muscular Dystrophy:\n\nGENETICS:\n\nX-linked recessive disease\n\nDMD gene encodes for a large protein DYSTROPHIN , which is required by muscle cells for structural support; it is thought to strengthen muscle cells by anchoring elements of internal cytoskeleton to the surface membrane. Without it, cell membrane becomes permeable, so that extra cellular components  enter the cell, increasing the internal pressure until the muscle cells explode and dies.\n\nType of Mutation found in DMD:\n\n* DMD with +ve family history =  Frame shift mutation (deletion or insertion)\n* DMD with -ve family history  =  Point Mutation\n* DMD in females =  X-chromosome & autosome translocation\n\nBeker’s Muscular Dystrophy :\n\nSame as DMD but  In-frame deletion or insertion producing altered protein dystrophin.\nIt’s a milder form of DMD\n----------------------------------------------------\nSYMPTOMS:\n\nEarly signs of Duchenne, which usually occur between the ages of 2 and 6, include frequent falling, difficulty getting up from a sitting or lying position, and a waddling gait. Another hallmark is the apparent enlargement of the calf and sometimes other muscles, which is really due to an accumulation of fat and connective tissue in the muscle. A blood sample shows a very high level of creatine kinase (CK), an enzyme that leaks out of damaged muscle.\nduchenne boys\n\nIn Duchenne muscular dystrophy, posture changes as the child grows.\n\nProgression varies somewhat from child to child. The use of orthopedic devices and physical therapy can prolong the ability to walk. Frequently, however, a wheelchair will be needed by age 12.\n\nMild mental retardation has been noted in some (by no means all) boys with Duchenne dystrophy.\n\nBreathing becomes affected during the later stages of Duchenne, leading to respiratory infections. These are often successfully treated with antibiotics and respiratory therapy. Severe respiratory and heart problems mark the disease's final stages, usually in the boy's teens or early 20s.\n------------------------------------------------------\nDIAGNOSIS:\n\n# Creatine Kinase Test \n# Electromyography and Nerve Conduction Velocities \n# Muscle Biopsies \n-------------------------------------------------------\nT/T:\n\nPrednisone \nDeflazacort \nAlbuterol \nCreatine\nAnabolic Steroids \nCalcium blockers  Gentamycin
448579
Usually due to a chemical imbalance in the muscle.
169899
It's actually a genetic syndrome.  There are certain phyical features associated with it (increased hairiness, short neck and stature are the ones I can think of without looking).  Check out WebMD (www.webmd.com) for more answers, and definitely talk to your doctor.  I know someone who was undiagnosed until she had a seizure.
848672
No, but a prion (affected protein) can induce the same prion pathological changes in healthy proteins.
254453
Wernig Hoffman Disease, also termed hereditary spinal muscular atrophy, is a disease of infants and young children that resembles amyotrophic lateral sclerosis. (spinal disease)Pathological changes are confined to the anterior horn cells of the cord and the cranial nerve motor nuclei. The disease affects all muscles to a varying degree. \n\nInfants with Werdnig Hoffmann disease may lack head control, may be unable to roll over or support their weight, and tend to lie relatively still, with little or no movement (flaccid paralysis). In addition, they may develop difficulties sucking, swallowing, and breathing; have an increased susceptibility to respiratory infections; or develop other complications that may lead to potentially life-threatening abnormalities within the first months or years of life. Intelligence is normal. Most affected children die before 2 years of age but survival may be dependent on the degree of respiratory function. \n\nFor infants who appear to have normal development for several months prior to the onset of muscle weakness, the disorder may tend to have a more slowly progressive course. Muscles of the pelvic, trunk, and shoulder areas may initially appear to be disproportionately affected. All muscles, with the exception of the eyes, are affected
496136
Not that I'm aware of. This genetic condition involves the X and Y chromosomes, and not anything else.
91572
There are VAST amount of different types of MD. Each one attacks its own set of muscles. Check out the link from the source.
815084
My brother also had male anorexia/muscle dysmorphia. He died at age 29 of heart failure due to complications however he was very muscular/low body fat and took way too many diuretics and/laxatives. Few people recognize male anorexia due to the fact that it is common in more females than males. Men also disguise a lot of their symptoms by stating they "work out a lot"\n  I was also diagnosed (anorexia/bulimia) at the age of 18 and have fought an uphill battle ever since. I have been in recovery since I was 26 and have found a healthier way to live. I and the Dr's do not think it ever goes away you just learn to handle it better and realize it IS psychological. Be ready HE WILL deny it and perhaps get agitated.\nI will think of you and him and I pray he gets the help he needs. Its a tough battle but one worth fighting to keep your life. \nPrayers and peace ~i~\n\nYou may want to look over these sites. The second link is a great resource for signs of the disorder. The third one is one mans story with the disorder.