How do you suppose the chaperones themselves manage to fold correctly?
436169
Many proteins fold correctly under basal conditions.  However, heat shock proteins and chaperones are just like any other protein, and may be aided in secondary and tertiary folding by other chaperonins.
577283
they exchange gas, when proportioned correctly, this can survive indefinately
318109
Most proteins function at peak efficiency at a certain temperature.  By maintaining a body at a set temp, animals can optimize their biochemical pathways.
585406
Sorry, my mother used to use that one when I was a kid, 50 years ago now, but I can't remember the folding. I have been sitting here for the last few munites trying to make it work and I can't. Might try Bible object lessons on a search.\n\nI found one site, not sure if it will help \nhttp://www.geocities.com/Heartland/Park/2601/PaperCutFold.htm
722594
I think most theoretical chemists would agree that the holy grail in the field would be accurate prediction of folded protein structure using only the primary amino acid sequence. \n\nWhat makes this difficult is the enormous size of proteins, the numerous non-bonded interactions, and the necessity to model solvent interactions with chemical accuracy. Even with accurate methods to do a single point energy calculation, you still have to find methods to effectively serach the conformational space to locate the global energy minimum. It's a big problem, and would definitely be worth a Nobel prize.
826242
rubbing 2 things together to create heat.\nRub yor hands together really fast and see what happens.
517670
Lay it flat, fold the sides inward (to meet in the middle), then fold in half, making sure the strings are on the bottom (closest to the floor), begin rolling from the opposite end of the bag, Roll it tightly. When you get to the end, pull the strings around the rolled up bag. Good Luck!
130615
Folding the flag:\n\nFlags, when not in use, should be folded into a triangle shape. The final triangle shape result is said to invoke the image of the three-point hats popular during the American Revolutionary War. Former American territories, e.g. the Philippines, also use this method to fold their flags.\n\nFolding the US Flag\n1. To properly fold the flag, begin by holding it waist-high with another person so that its surface is parallel to the ground. \n2. Fold the lower half of the stripe section lengthwise over the field of stars, holding the bottom and top edges securely. \n3. Fold the flag again lengthwise with the blue field on the outside. \n4. Make a triangular fold by bringing the striped corner of the folded edge to meet the open top edge of the flag. \n5. Turn the outer end point inward, parallel to the open edge, to form a second triangle. \n6. The triangular folding is continued until the entire length of the flag is folded in this manner. \n7. When the flag is completely folded, only a triangular blue field of stars should be visible.
668494
We know that the tempature is thousands of degrees farenheit, we also know they are 99% hydrogeyn gas.  They use nuclear fission or fussion to make energy.  All sorts of stuff.
289586
The function of a protein depends on its shape.  If you alter the shape of it, you alter its function.  pH is a factor that can alter the shape, because the pKa values of residues on the protein will dictate which residues are or are not protonated, and that will, in turn, affect the manner in which the various amino acids will form internal ionic bonds.\n\nTemperature is another factor.  the stability of intramolecular bonding is dependent on the level of thermal excitation.  If a protein is at a high temperature, the thermal motion of the atoms might upset their abilities to form bonds.  At really high heat, the result will be total denaturation.  At low temperatures, you might even have the opposite problem, with a protein clinging to things in the wrong ways.\n\nFinally, you might alter it by introducing a chemical that reacts with it.  Some proteins need activator molecules to function, others might be inactivated by an inhibitor.  Enzymatic activity occurs in what is called the "active site" of the protein, which is where the substrates bind to the protein and catalysis occurs.  So the activity of the molecule might be altered by changing the arrangement of the moieties in the acive site relative to one another, of there might be a change which permits/blocks access to the active site by the substrate molecules.
835650
Youve obviously already gotten the answer by now, but I want to add that this can actually be done on purpose. My mother and only one other person I have met can do this. Mom just says she folds the gum in half and it pops, but I cant seem to do it. ;P
266654
Picture a string of beads- the beads are different sizes and shapes. \n\nNow, "proteins" are basically like a string of beads that could be a very long string or a short string. AND instead of beads, there are amino acids- with different shapes and sizes. \n\nBut these strings don't lie flat. Depending upon the amino acids and other factors, the protein strings bend and fold in certain ways. So the string may become more like a ball or other strange shapes; this affects the way the protein works and interacts with other protein or chemicals. \n\nHope that mental picture helps answer your question...
282035
fold it in half u dummy!!!
811039
I will try. \nNot because it is difficult to understand but difficult to describe. Let us take a three member truss.\n\nA truss must be in equilibrium otherwise it will fall into its three component pieces. Lets assume it is for a roof\n\nFrom its apex to the two walls its load will come from the tiles, and for these the angles and weights are calculated to establish what portion of it goes to which joint.\nThe two portions at the top are examined together to make sure their loads will be stable against each other.\nThe portions at the bottom are being supported by two walls but they have two components each. One wants to rest on the wall while the other is trying to move away from the wall.\nTo keep this from happening we have to introduce our third truss member and make sure it can take the tension required of it.\nNow we know all the points we can show the summation of all the loads and ascertain if they are in compression or tension.\nWhen we have selected or designed each of our truss members we can fix them to keep the whole assembly stable.\nNow the truss it in equilibrium.\nTry it with large match sticks and think of what you are reading.\nIt might help.
994724
My freind Kyle knows how to do this. He had his own at one point.  But he isnt online right now. Im really sorry.. but if you keep this question open for a bit I can get back to you on this. \n\nHe just came online.. and im really sorry but he says it's very hard to explain! I really wish I could help though :(
415926
they want to bind w/ food. it helps get them absorbed.
590938
Im gullible!\n\nIf they ask you what came before an one celled organism, just say the complex protein structure which is the building blocks of life which is randomly spread out across the galaxy suspended in dirty ice. It only develops once condition are optimum for life to form, at least that should shut them up for a wee while.  \n\nAs for them the reason they get a little hot under the collar is that unlike us, they cannot provide an answer or even a theory  to suggest what was before God. Anyway didnt you know God has always existed?