Who is Thomas Scott Shoupe and what is his current research focus in the field of chemistry/biomolecular resea
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Looking in Pubmed, he is working in metabolic pathways involved in airways constriction, but he hasnt published anything listed on pubmed since 1994
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Major in biology\nAlthough there has been a tremendous revolution in the biological sciences in the past twenty years, there is still a great deal that remains to be discovered. The completion of the sequencing of the human genome, as well as the genomes of most agriculturally and scientifically important plants and animals, has increased the possibilities of genetic research immeasurably. Expedient and inexpensive access to comprehensive genetic data has become a reality, with billions of sequenced nucleotides already online and annotated. Now that the rapid sequencing of arbitrarily large genomes has become a simple, if not trivial affair, a much greater challenge will be elucidating function of the extraordinarily complex web of interacting proteins, dubbed the proteome, that constitutes and powers all living things. Genetic engineering has become the gold standard in protein research, and major research progress has been made using a wide variety of techniques, including:
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In the 1860s, German medical researcher Friedrich Miescher joined Felix Hoppe-Seyler’s laboratory at the University of Tubingen, Germany. There, at a time when scientists were still debating the concept of a “cell”, Hoppe-Seyler’s lab was isolating the very molecules that make up cells. \n\nMiescher was given the task of researching the composition of lymphoid cells -- white blood cells. These cells were difficult to extract from the lymph glands, but could be gathered in great quantities with the pus from infections. So Miescher collected bandages from a nearby clinic and washed off the pus. He experimented and isolated a new molecule – a white, slightly acidic substance he called nuclein. Isolated from the cell nucleus, nuclein – which was later purified to DNA -- was rich in nitrogen and phosphorus, as well as containing carbon, hydrogen, and oxygen. \n\nMiescher’s paper on nuclein was not published until 1871, two years after his discovery. Hoppe-Seyler, sceptical because nuclein was such a unusual molecule, confirmed the results by repeating all the experiments himself.
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I think most theoretical chemists would agree that the holy grail in the field would be accurate prediction of folded protein structure using only the primary amino acid sequence. \n\nWhat makes this difficult is the enormous size of proteins, the numerous non-bonded interactions, and the necessity to model solvent interactions with chemical accuracy. Even with accurate methods to do a single point energy calculation, you still have to find methods to effectively serach the conformational space to locate the global energy minimum. It's a big problem, and would definitely be worth a Nobel prize.
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Calvin cycle'''' (or Calvin-Benson cycle or carbon fixation) is a series of biochemical reactions that takes place in the stroma of chloroplasts in photosynthetic organisms. It was discovered by Melvin Calvin and Andrew Benson at the University of California, Berkeley. James Bassham also made important contributions to elucidating this pathway. It is one of the light-independent reactions or dark reactions.
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Pauling, Linus Carl (1901-1994), American chemist and physicist, whose investigations into the structure of molecules led to discoveries of how chemicals bond.\n\nPauling was born in Portland, Oregon, on February 28, 1901, and educated at Oregon State College and the California Institute of Technology. He began to apply his insights into quantum physics as Professor of Chemistry at the institute, where from 1927 to 1964 he made many of his discoveries. By devising techniques such as X-ray and electron diffraction, he was able to calculate interatomic distances and the angles between chemical bonds.\n\nDuring the 1930s Pauling introduced concepts that helped reveal the bonding forces of molecules. The Nature of the Chemical Bond, the result of these investigations, has been a major influence on scientific thinking since it was published in 1939. Pauling also investigated the atomic structure of proteins, including haemoglobin, and discovered that cell deformity in sickle-cell anaemia is caused by a genetic defect that influences the production of haemoglobin. He was awarded the 1954 Nobel Prize for Chemistry for his work. In later years Pauling fought ardently against nuclear weapons testing, warning the public of the biological dangers of radioactive fallout, and presented a petition to the United Nations in 1958 signed by over 11,000 other scientists. In 1962 he was awarded the Nobel Peace Prize, becoming the second person, after Marie Curie, to win two Nobel Prizes.\n\nThroughout his scientific career, Pauling followed his creative hunches, no matter how controversial they were. In 1970, for example, he advocated large doses of vitamin C to treat the common cold—a belief, however, that few medical authorities have endorsed.
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Check this out....\n\nhttp://www.sciencestuff.com/prod/Chem-Rgnts/C2043
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Ultimately, nobody knows at this point. But there are a number of guesses. I'd suggest reading the book "The Origins of Order" by Stuart Kauffman. His main point is that it is a whole collection of molecules that have to form, not just one self-replicator. So he looks at the deleopement of systems of interacting chemicals. At the very least, it's a thought provoking read.\n\nAnother thing to point out is that there is evidence that the original self-replicator was RNA, not DNA. Much of the cellular machinery to process DNA has RNA intricately involved, so that is not as much of a stretch as it might look.
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check out this link \n\nhttp://en.wikipedia.org/wiki/Cell_biology#Notable_cell_biologists
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Bio chemistry is actually study of chemistry of the life process of biological entities. It deals with the metabolism of food materials, i.e. how energy is generated from these and how building blocks (like amino acid, proteins and nucleic acids) of the body are made from them and like wise.Similarly it deals with differt types of harmones within living beings.Moreover it is now a differnt discipline in the study of science and covers a very wide area.
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You might be looking for information on alchemy, not chemistry.  The two fields of study are very seperate these days.  Of course, modern scientits could turn lead into gold by nuclear fusion, or turn heavier elements into gold by fission- neither process seems practical.
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http://biotech.icmb.utexas.edu/glycolysis/glycohome.html
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Try doing a Google search under the Hall or the Hall-Heroult process.    That or check out a General or an Inorganic Chemistry book from the library.  That's a good launch point.
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Right-the classic idea is that somehow nucleotides got together to form a self-replicating molecule (odds are that it was RNA at first, not DNA), and then these self-replicating molecules began to assemble amino acid chains, which, through uncounted bazillions of reacions (keep in mind whole oceans full of molecules, and billions of years) these amino acid/peptides began to have specific  functions.  The newest theory is that proteins formed (which is fairly easy with the right conditions), and some of these were captured in small mycells (little balls of lipids, which form naturally).  In some of them, the proteins interacted with each other to produce energy-generating reactions, and perhaps served as templates for formation of more of the same protein.  We now know this is as least theoretically possible, because of prion diseases, in which small proteins get into cells and cause generation of the same protein chain, independently of the DNA coding mechanism.  So, under this theory, you have mycells full of enzymes, energy-generating ( as in glycolysis or the TCA cycle) and only later did RNA or DNA come to play a role, as a more convenient and stable way to code for the proteins.  This makes a lot of sense biochemically, and is easier to visualize chemcically than the classic theory.  And, it makes sort of an elegant and chemically poetic argument that the origin of life was the thing that really makes life today-the proteins and the protein reaction-and relegates DNA to just a convenient way for the proteins to replicate.
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Well, if it's going to be double-spaced, front page only, with a title page and bibliography, it shouldn't be so intimidating. Find your topic, write a thesis, support it with three examples to back your thesis and close it. Voila!\n\nI have a great topic idea. It has all the characteristics you're looking for. Have you ever heard of a man named Esaru Emoto? He's an Japanese scientist who has taken photographs and done lots of studies of the different ways stimuli affect water molecules. Basically, his premise is this:  human beings are mostly water, our emotions and thought processes can actually transform the structure of the water molecules in our body. Put very simply, if you think negatively, the water molecules in your body (and those of the people around you even), will become jaded and jagged and irregular. Likewise, positive thoughts leave molecules smooth and beautiful, and void of jagged edges. His research seems to confirm the age-old saying "mind over matter." Just a thought. Kudos.
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Biochemistry is the study of the chemistry of life, a bridge between biology and chemistry that studies how complex chemical reactions give rise to life. It is a hybrid branch of chemistry which specialises in the chemical processes in living organisms. This article only discusses terrestrial biochemistry (carbon- and water-based), as all the life forms we know are on Earth. Since life forms alive today are believed to have descended from the same common ancestor, they naturally have similar biochemistries, even for matters which would appear to be essentially arbitrary, such as the genetic code or handedness of various biomolecules. It is unknown whether alternate biochemistries are possible or practical.\n\nBiochemistry is the study of the structure and function of cellular components, such as proteins, carbohydrates, lipids, nucleic acids, and other biomolecules. Chemical biology aims to answer many questions arising from biochemistry by using tools developed within synthetic chemistry.\n\nAlthough there is a vast number of different biomolecules, they tend to be composed of the same repeating subunits (called monomers), in different orders. Each class of biomolecules has a different set of subunits. Recently, biochemistry has focused more specifically on the chemistry of enzyme-catalyzed reactions, and on the properties of proteins.\n\nThe biochemistry of cell metabolism and the endocrine system has been extensively described. Other areas of biochemistry include the genetic code (DNA, RNA), protein synthesis, cell membrane transport, and signal transduction.
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It is the developing of technologies on the molecular scale in the field of biology. That's really the only way to describe it, I think. Why not look it up on wikipedia?