what is the mode of inheritance for the ABO blood group disease?
445758
Both parents contribute.\n\nA/A parent can only pass along A gene \nA/O parent can pass along either A or O gene \nB/B parent can only pass along B gene \nB/O parent can pass along either B or O gene \nO/O parent can only pass along O gene \nAB parent can pass along either A or B gene \n\nalso in the source about half way down page there is a list of offspring possibilitys listed.
60683
The McLeod phenotype was described by Allen et al. (1961) in a man of\n  that surname. His red cells showed unaccountably weak reactivity to Kell\n  antisera. In 1970, his red cells were noted to be acanthocytic in the\n  absence of abetalipoproteinemia. The precursor missing in McLeod's red\n  cells is called Kx. The X-linked locus determining this substance is\n  called Xk. Boys with chronic granulomatous disease lack Kx on\n  their phagocytic white cells and show acanthocytosis. McLeod had normal\n  white cell Kx and did not have granulomatous disease. He did have a\n  compensated hemolytic state (Wimer et al., 1976). Evidence for X-linkage\n  of Xk was provided by mosaicism in females for both acanthocytosis and\n  red cell Kx. The observations showed that some blood group antigenic\n  substances are important to both structure and function of cell\n  membranes.
12073
O+ is the most common, AB- is the rarest. \nOverall, the O blood type is the most common blood type in the world, although in some areas, such as Sweden and Norway, the A group dominates. The A antigen is overall more common than the B antigen. Since the AB blood type requires the presence of both A and B antigens, the AB blood type is the rarest of the ABO blood types. There are known racial and geographic distributions of the ABO blood types.\nFor more info refer to the source - wiki.
1004572
Yes.  O is a recessive gene, in this case, it doesn't produce an antigen.  A and B are both dominant, in this case, they both produce an antigen.  If the mother is BO and the father is AO, and both parents pass on the O gene, the child will be bloodtype O.
433957
A and B blood types are both dominant, so each parent could potentially be A0, and B0, meaning the children could be any combination of A,0 and B, 0, so: AB, A0, 0B, or OO.  The kid could be blood type A, B, AB, or 0.
94669
Yes, it is possible. The type B person could be type BO and the B is dominant so they are type B. The type A person could be type AO and the A is dominant so they are type A. If a BO person and an AO person have children, they're children have 25% change of being type O.
795936
in order for a child to have O blood, both parents must have one O allele (because O is recessive so the child needs 2 O alleles). Since we know that the father definitely has one A and the mother has one B, the parents' genotypes are\nmale: AO\nfemale: BO\n\n\nAO x BO\n\n-------A------O\n---B--AB----BO\n---O--AO---OO\n\nI hope you could understand my punnett square; using dashes for spacing is ugly! Their children will have 25% chance of AB blood, 25% A (genotype AO), 25% B (genotype BO), and 25% O.
217222
Their children will either be A or B.  One parent will give either an A or a B gene and the other can give only O.  Since O is a recessive gene it will take two of them to make an O child.\nGenotypes:\nParents:  \nAB\nOO\nChildren: \nAO\nBO\n\nIf they have only one child there is a 50% chance of A type and a 50% chance of B type.
427028
The differences in human blood are due to the presence or absence of certain protein molecules called antigens and antibodies. The antigens are located on the surface of the red blood cells and the antibodies are in the blood plasma. Individuals have different types and combinations of these molecules. The blood group you belong to depends on what you have inherited from your parents.\n\nThere are more than 20 genetically determined blood group systems known today, but the AB0 and Rh systems are the most important ones used for blood transfusions. Not all blood groups are compatible with each other. Mixing incompatible blood groups leads to blood clumping or agglutination, which is dangerous for individuals.\n\nNobel Laureate Karl Landsteiner was involved in the discovery of both the AB0 and Rh blood groups.\n\nCheck the full text\n\nhttp://nobelprize.org/medicine/educational/landsteiner/readmore.html
299475
It is not possible for a child of two O+ parents to have A+ blood.\n\nThe Rhesus factor (Rh) positive is not a problem - only one parent has to be positive.\n\nHowever, blood groups A, B, AB and O are determined by autosomal dominant transmission - this means that you only have to have one copy of the gene in order to express the trait, and they are not on the sex chromosomes, so both male and female children have equal chances of getting them.\n\nThe "A" and "B" just refer to two different proteins, called A and B (surprise). If you have one copy of the gene, YOU WILL HAVE THAT BLOOD TYPE. The only way to have O blood is to have two recessive O genes. Both parents *have* to be genotype OO. If they have one O and one A gene, then they will be blood type A.\n\nSo, if both parents are O, the ONLY possible blood group for their children is O. If the mother is O and the child is A, the father MUST be A.
588903
Sickle cell anemia is brought over (genetically) from parents to their children (if this what you mean). I don't really understand the questions.
228460
Codegirl gave a great answer, although she left out the possibility of your husband being AB and giving an A to make your child AA.  All I'd add is that you have to understand the difference between phenotype (which is the expressed form) versus the genotype (with is the combination of genes).  When you and your baby were typed, they only look at the phenotype, not the genotype.\n\nA person tested as A can be genotypically AA (A from both parents) or AO (A from one parent; O, which is recessive, from the other).\nA person tested as B can likewise be BB (B from both parents) or BO (B from one parent, O from the other).\nA person tested as AB must be genotypically AB, getting one from each parent.\nA person taht is tested as O must likewise be OO, getting O from each parent.\n\nA parent gives one of their two alleles to their child.  If you are AB, you could give your child either A or B.  Since their are two possible combinations of alleles that make A (AA and AO), the father might have contributed either an A or an O.  So the only thing known for certain about the father's genotype is that he is NOT BB.  He could be either AA, AB, or AO (and contributing an A to make your child genotypically AA), or he could be either BO, OO or AO (and contributed an O to make your child genotypically AO).  But phenotypically, the father could be anything: A, B, AB, or O.
799112
The children would have bloodtype A or bloodtype B.\n\nThe "O" which they get from one parent is merely an absence of the information necessary to have specific antibodies against other bloodtypes.
564737
A gene is part of a DNA molecule, particularly, the part of that DNA molecule required to make a gene product.  For instance, there is one gene that codes for the protein that determines ABO blood type.  You have two copies of that gene (they might be identical, or they might not be, depending on the gene), one from each parent.  For many genes, there exist different "versions" in a population, for instance, for the ABO blood type gene, there are three "version", or alleles of the gene, and we call them A,B and O.\n\nA genotype is a simple description of which alleles you have for a certain gene, or it might be a description of your alleles for a number of genes.  So, if you have the A allele of the ABO gene, and the B allele, your genotype is AB.\n\nMany diseases are caused by differences in a single gene, such as sickle-cell anemia.  People with one or two copies of a certain beta hemoglobin will suffer the affects of sickle-cell disease.  People with one copy of the disease-causing gene, and one copy of the “normal” gene will not have the full effects of sickle-cell, but they do have a non-normal phenotype.\n\nSome genetic diseases only manifest when a person has two copies of the disease causing alleles (we’d say that those alleles are recessive to the wild-type allele), some genetic diseases can be caused by having only a single copy of the allele (because the disease causing gene is totally dominant to the wild-type allele).  Some genetic diseases are incompletely penetrant; that is, some times, people who have two disease causing alleles won’t have the disease phenotype; either because of how the environment interacts with the gene, or because of other alleles in other genes interacting with the product of the disease gene, preventing the disease from manifesting.\n\nSome of the other answers on this board are making very broad statements about dominant “genes” (there’s really no such thing, there are only alleles which can be dominant to other alleles), or saying that diseases are only cause by carrying two recessive alleles (not true, some genetic diseases are caused by classically dominant alleles).  While a high-schooler might only learn about examples of genes that behave according to classical Mendelian rules, reality is a great deal more complex.  Diseases can be caused by classically recessive alleles, classically dominant alleles, alleles which are co-dominant to other alleles, alleles whose phenotpye is influenced by epigentic interactions with other genes...etc.
637142
no doesnt matter as far as blood groups go. AB, B, O whatever theyre all just as good. \n\nhowever, genetic testing to see if people carry a rececive gene that could result in diseases like cystic fibrosis or tay-sachs might be a good idea.... but you could always adopt or hope your kids dont get those diseases, so i wouldnt look to far into it. plus you might scare off your girl if you make her get all kinds of blood tests before you get married
117358
The "I" stands for Immunoglobulin.\n\nQuote: For the ABO gene, the three alleles are the IA, IB and i alleles. We typically call these alleles "A," "B," and "O," but of course our rules for assigning symbols to alleles demand that all three be represented by some version of the same symbol. In this case, that common symbol is the letter "I," which stands for "immunoglobin."
314497
All three of these answers above me are correct.  Your biological mother would have to be BO and your biological father would be AO and the O allele in each would be recessive, or not showing its trait because of the dominant a/b allele.  A Punnett Square would look something like this:  \nMOM    \n       ||||||||||  B |||  O  |\n       ------------\nD||     A| AB |  AO |\nA||     -------------\nD||     O| BO |  OO | <- That's you with type O blood.  If you had three siblings it would be likely that one would have AB blood, one type A blood, and one type B blood. \n       ------------