Are MRC-5 fibroblasts always from humans? Are they always from lungs?
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search for your protein on this site\n\nhttp://au.expasy.org/\n\nit tells what animals its in fuctions weight ETC
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Some cells don't regenerate ever (nerve cells).  Some cells are constantly regenerating (red blood cells).  Red blood cells only have a lifespan of a week.
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120-day life span, an RBC makes about 75,000 round trips between the lungs and tissues. At the end of its life, it returns to the bone marrow where it is removed by the reticuloendothelial system (particularly the liver, bone marrow, and spleen). Despite the constant destruction and production of RBCs (about 300 billion are destroyed and replaced each day), the body is able to maintain a fairly constant number
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Yes actually it is possible. Certain cells in the body only regenerate a specific # of times. Those cells tend to be what determines "natural death". Cells are capable of regenerating infinite numbers of times, and some do (like epithelial cells). If all of the cells of the body could be reprogrammed so that they didn't "count" when they regenerate, then yes it is possible to live forever. This is a question several institutions are beginning to work on, and several others have been working on since the 1970s.
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yes, all cells in/on your body carry your DNA
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From what I have gathered thru my search it is some kind of antibody.\nXenotropic murine-like retrovirus (XMRV) is closely related (96% genomic identity) to a group of retroviruses found in mice, xenotropic murine leukemia virus. Xenotropic means the virus crossed species.  Though such viruses can cause disease in animals other than mice, there has been no documented human infection until a recent report, in which the virus was detected in prostate cancer tissue.   The virus's link to human disease is still unclear, and more study is needed to determine the relationship, if any, between the virus and cancer.   While the genetics of prostate cancer are complex, one of the first genes implicated in the disease was RNASEL, a gene that serves as an important defense against viruses. Given the anti-viral role of this gene, some researchers have speculated that a virus could be involved in some types of prostate cancers in men with mutated RNASEL genes.\n\nIn the new study, the researchers discovered the novel virus far more often in human prostate tumors with two copies of the RNASEL gene mutation than in those with at least one normal copy. \nThe new finding further validates the strategy of using the virus chip to discover previously unknown viruses and potentially uncover new viral causes for disease, the researchers say. While most other virus identification techniques require researchers to look for only a small number of candidates, the virus chip represents an unbiased search, since all known viruses are tested simultaneously. \n\nThe study is part of an on-going effort launched two years ago by DeRisi and Ganem at UCSF, using the chip, or microarray, to search for new viruses associated with a wide range of human disease. So far, the chip has been used to search for novel viruses in about 300 cases of respiratory infections and about 50 cases of meningitis, as well as a dozen or more cases of severe encephalitis, and hepatitis and leukemia. \n\nIn the study, researchers examined tissue samples of 86 prostate cancer patients whose prostates had been surgically removed. Among the 20 prostate tumor samples from men with mutations in both copies of their RNASEL viral defense gene, eight of them, or 40 percent, contained the virus, while the virus was found in only one of 66 tumors from men with at least one normal copy of the gene. \n\nThe researchers don't know if the virus is unique to prostate tumors because this is the first tumor type they have studied using virus chip technology. As with most scientific discoveries, the identification of this virus in human prostate tissue prompts many more questions than it answers, they emphasize. \n\nThe gene-hunting technique DeRisi and Ganem call the Virochip is designed to identify any virus sample by comparing its DNA or RNA to more than 20,000 snippets of genetic material derived from all known viruses -- found in humans, animals, plants, fungi and bacteria. The chip draws on computer chip technology, computation and bioinformatics, but in essence it is a simple 3 x 1 inch glass microscope slide. Onto the slide the scientists robotically deposit 10 to 12 different DNA sequences from all known viruses. \n\nEach sample appears as a microscopic dot, about a tenth of a millimeter in diameter –giving it the name micoroarray. Researchers then wash fluorescently tagged DNA from a sample of interest over the slide, and wherever the two sets of nucleic acid match up, they anneal to each other. The slide is then rinsed and visualized with a scanning laser microscope. The dots that have found a match glow with fluorescent light. \n\n\nOctanol/Water Partition Coefficient \n The ratio of the amount of a substance that will dissolve in octanol versus the amount that will dissolve in water.  The higher the octanol/water partition coefficient the greater the tendency of substance to be stored in fatty tissues. \n \nOrganelle \n A subcellular structure such as the mitochondria or nucleus
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CLASSIFICATION OF CANCERS\nCarcinoma: malignant tumors derived from epithelial cells. This group represent the most common cancers, including the common forms of breast, prostate, lung and colon cancer. \nLymphoma and Leukemia: malignant tumors derived from blood and bone marrow cells \nSarcoma: malignant tumors derived from connective tissue, or mesenchymal cells \nMesothelioma: tumors derived from the mesothelial cells lining the peritoneum and the pleura. \nGlioma: tumors derived from brain cells \ngerm cell tumours: tumors derived from germ cells, normally found in the testicle and ovary \nChoriocarcinoma: malignant tumors derived from the placenta
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The plasmacytoid T cell or plasmacytoid monocyte--a sessile lymphoid cell with unique immunophenotype and unknown function, still awaiting lineage affiliation.\n\nClusters of cells with a plasmacytoid appearance have been identified in T zones of human lymphoid tissue. These cells were shown to express the CD4 antigen in the absence of B-cell antigens. Thus, they were named "plasmacytoid T cells" (PTCs). Recent studies, however, have suggested a myelomonocytic origin of this cell type, which led to the designation "plasmacytoid monocytes." In order to obtain a comprehensive immunophenotype of this cell, we used frozen serial sections of lymph nodes, an indirect immunoperoxidase technique, and a broad panel of well-defined monoclonal antibodies (mAbs). On PTCs, the antigenic density was high for CD4 and CD26 antigens and low for CD2; they furthermore reacted with the mAb OKM5 recognizing an undefined antigen associated with the myelomonocytic lineage and expressed the monocyte-associated antigen CD68. PTCs expressed HLA-A, B, C, HLA-DR, and the HLA-D associated invariant chain (Ii) while HLA-DP antigens were expressed only in low amounts and HLA-DQ antigens were lacking entirely. PTCs further expressed the adhesion molecule CD11c. The absence of detectable transferrin receptor and the proliferation antigen defined by Ki-67 indicated that PTCs were nonproliferating. Other well-defined antigens confined to the T-, B-, and myelomonocyte lineages could not be detected in the target cell population. For us, antigenic equipment is still suggestive of a sessile, terminally differentiated T cell likely to exert a secretory function as yet unknown.
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Fibroblasts have a branched cytoplasm surrounding an elliptical, speckled nucleus having 1 or 2 nucleoli. Active fibroblasts can be recognized by their abundant rough endoplasmic reticulum. Inactive fibroblasts, which are also called fibrocytes, are smaller and spindle shaped. They have a reduced rough endoplasmic reticulum.\nEpithelial tissues cover or line all body parts both externally and internally. With cells tightly packed together and with little intercellular space, the epithelial tissues form effective barriers between underlying tissues and external media. Thus, the epithelial tissues are extremely important in regulating the exchange of materials between different body parts. The portions of cell membranes found on the outer surface of an epithelial tissue are specialized to act as the regulators of the tissue strictly managing the flow of materials into and out of the epithelium. In contrast, those portions of cell membranes that are adjacent only to other epithelial cell membranes allow a less restricted flow of materials between epithelial cells. The outside surfaces of epithelial tissues often are highly specialized in other ways possessing cilia, hairs, or glands, which may arise from individual cells or groups of cells that have invaginated and which are capable of covering the outer surface of an epithelial tissue with mucous or waxy secretions. Epithelial tissues are separated from underlying tissues by extra cellular basement membranes. \nThree types of epithelial cells exist: Squamous cells are thin and flat, cuboidal cells have a square shape in section and a polygonal shape when looking at the surface of a tissue, and columnar cells are much taller than they are wide. Simple epithelial tissues are only one cell-layer thick and are named on the basis of their cell type: Simple squamous, simple cuboidal, and simple columnar epithelia are the three types of simple epithelial tissues.
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there are various stem cell lines but they are not all totipotent (meaning they can convert to any cell line in the body) most of them are in locations where constant renewal of cells are necessary like the lumen of the gut or the bone marrow or the reproductive tract. They are caller pluripotent (they can form multiple cell lines but not all) and are used in as i said repairng the organ as cells from that are worn out or simply die or ejaculated (blood and sperm or egg respectively)\n\nthey are also pretty useful in performing genomic assays in adult organisms to see how they react to injury or chemical stress
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Parenchyma cells are the most abundant.  They are undifferentiated and fill the spaces between more specialized tissues, and are involved in wound healing.
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There is a great deal missing from this article. Whether or not it is life is questionable. That the material is called "cells" indicates that the material is self-reproducing 'autonomously', and I don't know that's been proved yet.\n\nAlso, yet to be proved, is the idea that the material is of extraterrestrial origin. There are many new types of life being found on earth almost daily. True most of these are just variations of species, but we are finding life in places never before thought possible.\n\nWithout DNA, some other sort of self-replication mechanism needs to be present, and the article made no claims to what form this mechanism takes. I would need to see a great deal more to be convinced of any of the claims made in the article.\n\nThat's not to say I couldn't believe, but I just need more information.
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Depends on the cell type labile, stable, non regenerative etc
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Miike,\n\nReally technical question,  one reference :\n\nhttp://www.cellculture.com/turbosystem.html\n\nlooks like they use both SP2 and the P3 lines to increase longevity.\n\nIf you are doing research at University or at non profit,  I would pose the question to the IMF / MMRF science committee and ask them: \n\nThey could possibly give you some case history for myeloma cell lines and which ones produce best with B cells  \n\n\nGood luck,\n\nJewells\n27 months and still here
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red blood cells (erythrocytes),  white blood cells (lymphocytes) (lots of different types),  phagocytes, macrophages, platelets (sticky part of blood), stem cells, nerve cells, sperm cells, egg cells, fibroblasts, epithelial cells (ciliated and otherwise), gastric mucosal cells, fat cells, islets of Langerhans (is that right?  pancreas), helper cells (immune system) - will that do to start?
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well since the cells are from your own body... you're going to continue to be susceptible to genetic conditions.\n\ni guess, offhand, let's say you have cystic fibrosis and you want to have a lung transplant through therapeutic cloning.\n\nthe defect in the lungs is caused by a mutant gene that is present in your cells. because this gene is still present in the cloned cells, the cloned lung will have the same defect as the one you're looking to replace. so that's one problem.\n\nsince this hasn't been done yet, we can't tell for sure what complications could occur during the process of organ development and how that would impact the health of the transplantee.
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He's right it's really mylein, whoever made the test that some of your bio multiple choice questions came from did a crappy job :-P.  The answer you need is Schwann cells because they make the mylein, which really should be the answer.  Schwann cells only make mylein in the peripheral nervous system though.  Oligodendrocites make it in the central nervous system.