i need a comparison between oxyplatin & cisplatin, including efficacy, safety?
96576
Cisplatin is the most potent nausea and vomitting inducing Anticancer agent more than oxyplatin. Oxyplatin is not in oral form must be given with leukovorin to reduce neurotoxicity. When giving Oxyplatin, tell patients to avoid cold food or environments.
1113658
I was diagnosed with cancer of the larynx in the final stages but refused to have my vocal cords removed creating somewhat a delemia with my treating doctor. I was hell bent on saving my voice. After double the dosage of radiation ( enough to kill a perso ) by error and chemo alongwith the same, my cancer came under control. This was in April 2000. The side effects of the radiation have left some scars that will always remain with me - I developed a fistula between my air and food passage making it impossible for me to eat or drink any thing. Even breathing became a problem and an emergency tracheostomy had to be done. The doctors felt that the fistula should be left alone as they normally heal by themselves but not in my case! The overdose had taken its toll. Meanwhile,as I could not eat anything - a peg ( feeding) tube was inserted into my stomach which ment no solids and only liquids. My wife and mother fomulated some really high protien and energy feeds that kept adding to my weight that I had lost and got me back to where I was.\nIts now been five and half years since I last even had a drop of water orally and everything is fed through the peg tube - either by pouring it down , if its totally liquid or by pushing it through the tube as in the form of an injection. I have been told that my fistulas will never heal by themselves and that means I am stuck with a stoma ( not permanent ) and a tube in my stomach - waiting for another miracle. The doctors were / are quite sure my air and food passage can be reconstructed by skin grafting but that would have to be done in phases and that in turn means spending time in the hospital. I have had enough of hospitals and decided to live my life out with the stoma ( for which I created an orator and can speak normally, hands free ) and as I have got pretty used to the peg tube it does not bother me anymore.\nI still carry on with my job as I did pre cancer. I have added a personel gym next to my office where I work out for an hour every evening and go for a four kilometre run/jog every morning. \nI look forward to a new day every day with a lot of positiveness and find myself getting closer to my two teenaged sons and falling in love with my wife all over again. I am no longer the worklaholic that I once was and take time off to be with my family. I have cut down on my travelling at the drop of a hat and rather have someone else do it. I have adopted 25 kids of who some are terminal. I make sure they receive all their medicines, hospital expenses, food and lodging at my expense. I also ensure that they receive a good deal of financial aid as all these kids come from families that cannot afford even one meal a day - let alone three that we all have.\nWell I dont know how long I have left and even though I have been declared cancer free - one never is. I want  lead a full life like I have always led - king size. I have no regrets and no complaints against the cancer. I was chosen to get it- I fought it and am alive for my  sons and wife. I can also relate to others who have /are going through this illness and I think this makes my life complete. Cancer is a teacher of sorts and if you pick up the valuable lessons it teaches you - you can fight it and reap all the benefits of life from it. Benefits that you would never have considered had you not been the chosen one.\nI dont know if this makes any sense - but then each one has/her opinionand I chose cancer as a techer.
908886
My understanding Cobalt 60 is more precise.  It is a new technology, not available everywhere.  Radium is use more universally.  Radiation therapy works best when the cancer is caught early.  Late discovery is more difficult.
577637
I've had lymphoma, and underwent chemotherapy.  I knew I had to live for the sake of my wife and children.  If I'd been 94, I guess I would have just said my goodbyes and told people I was going to be with the Lord.  \n\nIn this woman's case, there might be some treatments that would be effective without most of the bad effects of chemotherapy.  Rituximab is one drug like that.  \n\nLetting nature take its course with lymphoma is not nearly as bad as with other forms of cancer.  It's mostly just getting weaker, and relatively little pain, unlike many other cancers.
123092
Hi .. this is a tough one. Paclitaxel (TAXOL) is most commonly used in combination chemotheraphy, ie with some other anticancer drug, most commonly, it would be doxorubicin. The regimens vary according to pre-operative staging and biopsy findings, however there would be most commonly up to 6-8 cycles of chemotherapy, 1 cycle every 3 weeks makes it 18-24 weeks. Again it is really hard to tell as no data provided.
762099
Google L690.......All you can find is that it is a chemotherapy drug.  Haven't seen any images.
1007385
Most chemotherapy drugs kills cells while they are dividing. Cancer cells divide faster then normal cells.  That is why the chemo kills cancer cells more than normal cells.  Other cells that divide fast are immune cells, blood cells, hair cells and the cells in the lining of the stomach.  This is why the side effects of may chemo agents are immunosuppression, anemia, hair loss and mucositis/stomatitis.  \n\nDifferent chemo agents stop the cell cycle in different ways.  Some are antimetabolites and block the use of vitamin necessary for cell division.  Some bind to the tubules and don't allow the cell to divide.  The mechanisms vary but the end result is the same.  Cell death.
107173
Nicvax\n\nhttp://www.nabi.com/pipeline/pipeline.php?id=3
653227
Bad news:  this is not curable\nGood news:  if the cancer mets are restricted to her bones only, she may have many years left.  Zometa (zoledronic acid) is definitely a good option, as is Taxotere (very well tolerated chemotherapy).  She DEFINITELY needs to have  Her-2 neu test to see if she would benefit from Herceptin (they should be able to perform this test on the tissue they have from her previous surgery, or on new tissue if she has another biopsy).  \n\nAlso, if she is getting her period regularly, her doctor may advise ovarian ablation or lupron therapy, since she is PR +.  \n\nGood luck on the PET scan.
75338
AnhydrousCyclophosphamide\n\n\nA synthetic alkylating agent chemically related to the nitrogen mustards with antineoplastic and immunosuppressive activities. In the liver, cyclophosphamide is converted to the active metabolites aldophosphamide and phosphoramide mustard, which bind to DNA, thereby inhibiting DNA replication and initiating cell death.
617145
Amoxicilin, but it can take up to 30 days to work\nZ-pac is great, worked for me in only a week
351215
A lot. A good one is the interaction with the anticancer drug cisplatin. It is actually platinum metal which binds to the DNA of cancer cells, inhibiting them from further multiplying. There are also silver and gold which bind to DNA and form nano-sized particles which are hot hot hot topic right now.
325816
I had cancer in my colon,bladder, ovaries and appendix. I was on chemo before and after. It was called Xeloda. I was on it for 6 months. It is in pill formation and it has alot less side affects. I had no hair loss and very little nausea. I read in recent articles that it is just as effective if not more than other chemos available. It was giving to me by a local hospital and then by Memorial Sloan Kettering. Ask your oncologist about it but always listen to what they think is best for you. There are over 3,000 different chemos and they would know what would work best for you. I'm Cancer free for a year now and I wish you the same. Good Luck and God Bless!
708668
Que Paso Gringo,\n\nWith all due respect to the other participants answering this question, WHAT THE HELL IS SO GOOD AND EFFECTIVE ABOUT SCIENTIFICALY PROVEN CHEMO AND RADIATION?\n\nIm a natural health practitioner and people who state that EDTA CHELATION its not PROVEN or not SCIENTIFICALY APPROVED are obviously ignorant and have never had the insidious deisease nor have any of their friends or relatives, and God forbid they do, cause those SCIENTIFICALY PROVEN alopathic methods surely will cause an extreme amount of damage besides burning all cells, good and bad, in the system.\n\nI have used EDTA successfuly for Diabetics and Cancer patients along with a proper PH balance and stress control, all contributing factors to any disease.\n\nNone other than a true American Hero such as Dr. Linus Pauling have endorsed EDTA CHELATION for effective non invasive cancer treatments. Linus Pauling, PhD is the only person ever to have received 2 FULL, UNSHARED Nobel Prizes. He was one of the world's greatest biochemists and scientists. Before his death he wrote and researched extensively in the field of alternative and nutritional medicine.\n\nFor more than twenty years Dr. Pauling devoted most of his time to research and educate in the fields of nutrition and preventive medicine. He wrote and lectured extensively about simple, safe and inexpensive measures to improve the length and quality of life. In his recent books, How to Live Longer and Feel Better, he covered that subject at length. \n\nDr. Pauling stated that EDTA chelation therapy fits in well with his views on health care. SO IF THE ESTEEMED FELLOWS ANSWERING THIS QUESTION CAN CALL DR. PAULING A QUACK then it confirms their motives for writing such a ridiculous statement for all the world to see. \n\nAmigo, EDTA is not normally present in the human body and is therefore, by definition, not an Orthomolecular substance. Chelation, however, is far safer and much less expensive than surgical treatments for atherosclerosis. Physicians who adhere to the protocol for safe and effective administration of EDTA, as approved and promulgated by the American College of Advancement in Medicine, integrate the results of the proven research into their chelation program. \n\nThat protocol is published in its entirety fro any medical prefsional or potential patient to review. Improved nutrition and supplementation with vitamins and trace elements is an important part of the overall chelation program. \n\nEDTA chelation therapy makes good sense, It has a rational scientific basis, and the evidence for clinical benefit seems to be quite strong. Metallic ions play an important role in the formation of atherosclerotic plaque. EDTA removes those ions with relative safety and without surgery. Published research and extensive clinical experience show that EDTA helps to reduce and prevent atherosclerotic plaques, thus improving blood flow to the heart and other organs. The scientific evidence indicates that a course of EDTA chelation therapy might eliminate the need for bypass surgery. Chelation has an equally valid rationale for use as a preventive treatment. \n\nFurthermore, yet ANOTHER Nobel Prize winner, and yes this Doctor also won 2 Nobel Prizes, one in 1931 and the other in 1938, Dr. Otto Werberg of Germany, who discovered that cancer is formed when the cells and tissues are "anaerobic", with out sufficent oxygen. EDTA chelation accelerates de detox process removing the excess acid in the body, thereby raising the Alkaline level or oxigen level for all functions of the body and once this is achieved, no way that any tumor, harmful bacteria, germs, parasites or fungus can stay alive in the body, it all now gets naturaly excreted by the waste system.\n\nTherefore, the decision should be obvious, use an alternative treatment that is LEGAL and EFFECTIVE, that costs considerably less than traditional alopathic methods and DOES not cause any secondary damage to the body.\n\nAt your service
288356
try this site\n\nwww.oxinium.co.uk
457951
What is chemotherapy?\n\nTreatment with drugs to kill cancer cells is called chemotherapy. \n\nHow is chemotherapy given?\n\nMost anticancer drugs are injected into a vein (IV) or a muscle. Some are given by mouth. Chemotherapy is systemic treatment, meaning that the drugs flow through the bloodstream to nearly every part of the body. \n\nOften, patients who need many doses of IV chemotherapy receive the drugs through a catheter (a thin flexible tube). One end of the catheter is placed in a large vein in the chest. The other end is outside the body or attached to a small device just under the skin. Anticancer drugs are given through the catheter. This can make chemotherapy more comfortable for the patient. Patients and their families are shown how to care for the catheter and keep it clean. For some types of cancer, doctors are studying whether it helps to put anticancer drugs directly into the affected area. \n\nWhen and where is chemotherapy given?\n\nChemotherapy is generally given in cycles: a treatment period is followed by a recovery period, then another treatment period, and so on. Usually a patient has chemotherapy as an outpatient at the hospital, at the doctor's office, or at home. However, depending on which drugs are given and the patient's general health, the patient may need to stay in the hospital for a short time. \n\nWhat are side effects of chemotherapy?\n\nThe side effects of chemotherapy depend mainly on the drugs and the doses the patient receives. Generally, anticancer drugs affect cells that divide rapidly. These include blood cells, which fight infection, help the blood to clot, or carry oxygen to all parts of the body. When blood cells are affected by anticancer drugs, patients are more likely to develop infections, may bruise or bleed easily, and may have less energy. To prevent infections, patients taking chemotherapy should wash their hands frequently, avoid sick people and crowds, immediately clean cuts and scrapes, avoid contact with animal waste, and notify their doctor if they develop chills, sweats or fever at 101 degrees or greater. To prevent bleeding, they must avoid aspirin, ibuprofen, or any medication without the consent of their doctor and avoid cuts with razors, knives, etc. The doctor should be notified with any signs of bleeding, such as blood in stools, vaginal spotting, bleeding gums, vomiting or coughing up blood, and bruising. \n\nCells that line the digestive tract also divide rapidly. As a result of chemotherapy, patients can have side effects the affect the mouth, stomach and intestines, such as loss of appetite, nausea and vomiting, or mouth sores. For some patients, medicines can be prescribed to help with side effects, especially with nausea and vomiting. To reduce nausea and vomiting, patients can eat frequent, small meals, have liquids at least one hour before or after eating, eat foods at room temperature, eat slowly, avoid offensive odors, rest after eating, and breath through the mouth if nausea develops. Usually these side effects gradually go away during the recovery period or after treatment stops. Mouth soreness can be minimized with the use of a soft toothbrush, soothing mouth rinse with a teaspoon of baking soda in warm water, and lip balm. High acid foods and juices, such as tomato, orange or grapefruit, should be avoided. \n\nHair loss, another side effect of chemotherapy, is a major concern for many patients. Some chemotherapy drugs only cause the hair to thin out, while others may result in the loss of all body hair. Patients may feel better if they decide how to handle hair loss before starting treatment. \n\nIn some men and women, chemotherapy drugs cause changes that may result in a loss of fertility (the ability to have children). Loss of fertility can be temporary or permanent depending on the drugs used and the patient's age. For men, sperm banking before treatment may be a choice. Women's menstrual periods may stop, and they may have hot
205680
Chemotherapy is the treatment of cancer using specific chemical agents or drugs that are selectively destructive to malignant cells and tissues. \n\nBasically, it's poison to kill the cancer.  Chemotherapy is usually a combination of drugs to specifically target certain kinds of cancer.  Unfortunately, science doesn't always allow the chemicals to be a specific as we want them to be...so there are some side effects as a result.