is urea toxic to the body?
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Urea can be irritating to skin, eyes, and the respiratory tract. Repeated or prolonged contact with urea in fertilizer form on the skin may cause dermatitis. High concentrations in the blood can be damaging.
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Parenteral use may cause allergic/anaphylactic reactions. Blood urea levels may rise in patients with compromised renal function due to severe heart failure [7]. Caution is recommended in pregnancy, lactation and patients dependent on preload for maintenance of cardiac output [8].
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Your body treats ammonia as a waste product, and gets rid of it through the liver. It can be added to other chemicals to form an amino acid called glutamine. It can also be used to form a chemical compound called urea. Your bloodstream moves the urea to your kidneys, where it is eliminated in your urine.
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Skin or eye contact: Exposure to low concentrations of ammonia in air or solution may produce rapid skin or eye irritation. Higher concentrations of ammonia may cause severe injury and burns.
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Urea is end product of protein metabolism and results.
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If your blood sample is being tested only for blood urea nitrogen, you can eat and drink normally before the test. If your blood sample will be used for additional tests, you may need to fast for a certain amount of time before the test. Your doctor will give you specific instructions.
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Mixing bleach and ammonia can be deadly. When combined, these two common household cleaners release toxic chloramine gas. Exposure to chloramine gas can cause irritation to your eyes, nose, throat, and lungs. In high concentrations, it can lead to coma and death.
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Metabolic wastes like urea, carbon dioxide, uric acid, creatinine and sodium chloride are present in normal urine. The presence of proteins, glucose, ketones, red blood cells, however, indicate malfunction of the kidneys or some other organ of the body.
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When kidneys fail, urea that builds up in the blood can cause diabetes, concludes a study published today in the Journal of Clinical Investigation. "We identified molecular mechanisms that may be responsible for increased blood glucose levels in patients with non-diabetic chronic kidney disease.
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Most of the Ca++, Na+, glucose, and amino acids must be reabsorbed by the nephron to maintain homeostatic plasma concentrations. Other substances, such as urea, K+, ammonia (NH3), creatinine, and some drugs are secreted into the filtrate as waste products.
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Low urea levels are not common and are not usually a cause for concern. They can be seen in severe liver disease or malnutrition but are not used to diagnose or monitor these conditions. Low urea levels are also seen in normal pregnancy. Urea levels increase with age and also with the amount of protein in your diet.
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There's also evidence that, in the long term, consuming too much protein can lead to an increased risk of osteoporosis and can also worsen existing kidney problems. The Department of Health advises adults to avoid consuming more than twice the recommended daily intake of protein (55.5g for men and 45g for women).
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Urea, also known as carbamide, is an organic compound with chemical formula CO(NH2)2. This amide has two –NH2 groups joined by a carbonyl (C=O) functional group.
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Total Dissolved Solids Urine has large amounts of nitrogen, phosphorus, and potassium. Nitrogen content in urine is high, mostly in urea, which makes up more than 50 percent of the total organic acids. This includes urea from protein metabolism, sodium and potassium both of which come from food.
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In the US and a few other countries, plasma or serum urea concentration is expressed as the amount of urea nitrogen. Although plasma or serum is used for the analysis, the test is still, somewhat confusingly, commonly referred to as blood urea nitrogen (BUN), and the unit of BUN concentration is mg/dL.
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So the liver converts the ammonia to a non-toxic compound, urea, which can then be safely transported in the blood to the kidneys, where it is eliminated in urine. An adult typically excretes about 25 grams of urea per day.
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If your kidneys cannot handle the load of urea, the nitrogen is excreted in your sweat as ammonia. The best way to prevent the smell is to be sure you have enough carbohydrate fuel for your exercise.