what are the long term side effects of proton pump inhibitors?
537364
Although PPIs have had an encouraging safety profile, recent studies regarding the long-term use of PPI medications have noted potential adverse effects, including risk of fractures, pneumonia, Clostridium difficile diarrhea, hypomagnesemia, vitamin B12 deficiency, chronic kidney disease, and dementia.
43016
['Nausea.', 'Diarrhea or constipation.', 'Heartburn.', 'Increased intestinal gas.']
1335827
['Abdominal pain.', 'Constipation.', 'Diarrhea.', 'Dry mouth.', 'Flatulence.', 'Headache.', 'Nausea.', 'Somnolence (drowsiness or sleepiness)']
221322
['headache.', 'diarrhea.', 'nausea.', 'gas.', 'abdominal pain.', 'constipation.', 'dry mouth.', 'drowsiness.']
1255298
['headache,', 'dizziness,', 'drowsiness,', 'stomach or abdominal pain,', 'upset stomach,', 'diarrhea,', 'heartburn,', 'loss of appetite, and.']
89419
Long-term side effects In a study lasting 12 months, the most common side effects of MiraLAX were: diarrhea or loose stools. gas (flatulence) nausea.
793267
['nausea, heartburn;', 'headache;', 'joint pain; or.', 'feeling tired.']
174622
['constipation, diarrhea;', 'nausea, vomiting, heartburn;', 'stomach pain, upset stomach;', 'black or dark-colored stools or urine;', 'temporary staining of the teeth;', 'headache; or.', 'unusual or unpleasant taste in your mouth.']
301837
['stomach upset,', 'nausea,', 'drowsiness,', 'diarrhea,', 'bloating,', 'gas,', 'dizziness,', 'nervousness,']
7336
['nausea.', 'indigestion.', 'vomiting.', 'diarrhea.', 'bloating.', 'feeling of fullness.', 'loss of appetite.', 'stomach cramping or pain.']
1276278
['heartburn.', 'gas.', 'stomachache.', 'burning in the mouth.']
409141
['nausea.', 'vomiting.', 'diarrhea.', 'gas.', 'abdominal pain.']
187673
Tell your doctor right away if you develop: persistent diarrhea, abdominal or stomach pain/cramping, fever, blood/mucus in your stool. Rarely, proton pump inhibitors (such as omeprazole) have caused vitamin B-12 deficiency. The risk is increased if they are taken every day for a long time (3 years or longer).
719952
Long-term side effects Some side effects that may occur with long-term use include: constipation. blurred vision. memory problems and dementia (especially in seniors)
1134569
['Diarrhea.', 'Gas.', 'Headache.', 'Intense Abdominal Pain.', 'Vomiting.']
1305779
['nausea and vomiting.', 'dry mouth, or xerostomia.', 'indigestion.', 'peptic ulcers.', 'diarrhea.', 'heartburn.']
369258
['Nausea.', 'Heartburn.', 'Diarrhea.', 'Constipation.', 'Drowsiness.', 'Skin reactions.', 'Headache.']