what does carrying the sickle cell trait mean?
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If an individual has sickle cell trait, it means that he or she carries or has inherited a single copy of the gene that causes sickle cell disease. It is not a disease. In general, people with sickle cell trait enjoy normal life spans with no medical problems related to sickle cell trait.
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Key points. Sickle cell disease is an inherited blood disorder marked by defective hemoglobin. It inhibits the ability of hemoglobin in red blood cells to carry oxygen. Sickle cells tend to stick together, blocking small blood vessels causing painful and damaging complications.
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Key points about sickle cell disease in children Sickle cell disease (SCD) is an inherited blood disorder that is present at birth. This means it is passed down through a parent's genes. With SCD, the red blood cells have an abnormal C shape. They get stuck in small blood vessels and block blood flow.
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Sickle cell anemia is inherited in an autosomal recessive pattern, which means that both copies of the gene in each cell have mutations . The parents of an individual with an autosomal recessive condition each carry one copy of the mutated gene, but they typically do not show signs and symptoms of the condition.
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Sickle Cell Anaemia is called a recessive condition because you must have two copies of the sickle haemoglobin gene to have the disorder.
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Such mutated or abnormal hemoglobin can create RBCs that are sickle-shaped, leading to SCD. A sickle cell test looks only for the presence of hemoglobin S, which causes SCD. A negative test is normal. It means your hemoglobin is normal. A positive test result may mean you have sickle cell trait or SCD.
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Carriers of sickle cell (sickle cell trait) A carrier of sickle cell is someone who carries the gene that causes sickle cell disease but does not have sickle cell disease themselves. It's also known as having the sickle cell trait.
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The disease gets its name because when you have SCD, your red blood cells look like a sickle, which is a C-shaped farm tool. Red blood cells contain a molecule called hemoglobin, which carries oxygen throughout the body. In a healthy person, hemoglobin is smooth, round, and flexible.
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Description. Sickle cell disease is a group of disorders that affects hemoglobin, the molecule in red blood cells that delivers oxygen to cells throughout the body. People with this disorder have atypical hemoglobin molecules called hemoglobin S, which can distort red blood cells into a sickle, or crescent, shape.
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Cells with a markedly increased Hb S concentration are a prominent feature of sickle cell disease, as a consequence of the loss of K, Cl and water from the erythrocyte. The extreme dependence of polymerization kinetics on Hb S concentration means that these dehydrated erythrocytes rapidly sickle when deoxygenated.
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A sickle cell prep is a screening test done on blood to find if sickle cell trait or sickle cell disease is present. Sickle cell trait or disease happens when an abnormal hemoglobin (heem-uh-glo-bun) called hemoglobin S is in the blood.
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A sickle cell test is a blood test done to check for sickle cell trait or sickle cell disease. Sickle cell disease is an inherited blood disease that causes red blood cells to be deformed (sickle-shaped).
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The lower HbA1c levels experienced by people with sickle cell trait could lead to doctors underestimating the risk of prediabetes or diabetes and could lead to delayed diagnoses.
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Sickle cell disease (SCD) is a group of inherited red blood cell disorders. If you have SCD, there is a problem with your hemoglobin. Hemoglobin is a protein in red blood cells that carries oxygen throughout the body. With SCD, the hemoglobin forms into stiff rods within the red blood cells.
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Sickle cell trait is not a benign condition and continues to be associated with sudden death in individuals during periods of extreme physical exertion.
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Inheritance of sickle cell anemia. Sickle cell anemia is an autosomal recessive disease, meaning that it only occurs if both the maternal and paternal copies of the HBB gene are defective.
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Hemoglobin SC disease, is a type of sickle cell disease, which means it affects the shape of the red blood cells . Red blood cells contain a protein called hemoglobin, which is responsible for carrying blood throughout the body.