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Abstract:

Introduction . Previous studies suggest that the severity of alterations in cognitive functions in people with a diagnosis of bipolar I disorder ( BP - I ) are directly related to the deterioration in overall functioning and life quality . Altered cognitive function is associated with a worse prognosis of BP - I , however little is known about the relationship between cognitive functions and the clinical features of BP - I . Objective . To establish possible associations between cognitive function and the clinical and socio - demographic characteristics of patients with BP - I . Methods . Cognitive function was evaluated by applying a neuropsychological battery to a group of patients with a BP - I diagnosis , who did not have affective episodes for at least 6 months , and who were outpatients treated at the San Juan de Dios Clinic in Manizales . The statistical analysis involved using clustering methocology in order to divide those patients with the best and worst cognitive function and it was later correlated with the clinical and socio - demographic variables . Results . A statistically significant corrrelation was found between the number of years of education and the age the disorder started with alterations in the level of cognitive function ( P= .002 and P= .017 respectively ) . No significant correlations were found with other variables . Conclusions . An early onset of the pathology and fewer years of education seems to be risk factors associated with poorer cognitive function in patients with BP - I . 
alterations in cognitive functions
Altered cognitive function