is clopidogrel an ace inhibitor?
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Aims. Clopidogrel and angiotensin converting enzyme (ACE) inhibitors are commonly co-prescribed drugs. Clopidogrel inhibits carboxylesterase 1 (CES1), the enzyme responsible for converting prodrug ACE inhibitors (such as ramipril and perindopril) to their active metabolites.
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Aspirin and Plavix (clopidogrel bisulfate) are drugs used to prevent blood clots. Aspirin and Plavix belong to different drug classes. Plavix is an anticoagulant and aspirin is a nonsteroidal anti-inflammatory drug (NSAID). Aspirin also is used to reduce fever, and to treat pain and inflammation in the body.
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ACE inhibitors Angiotensin-converting enzyme (ACE) inhibitors reduce blood pressure by relaxing your blood vessels. Common examples are enalapril, lisinopril, perindopril and ramipril. The most common side effect is a persistent dry cough. Other possible side effects include headaches, dizziness and a rash.
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ACE inhibitors are associated with a dry, persistent cough in 5%-35% of patients who take them. The mechanism of cough is likely multifactorial. ACE inhibitors prevent the breakdown of bradykinin and substance P, resulting in an accumulation of these protussive mediators in the respiratory tract.
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- Patients who use clopidogrel and need a medication to reduce stomach acid can use antacids and most H2 blockers such as Zantac (ranitidine), Pepcid (famotidine), Axid (nizatidine), but not Tagamet and Tagamet HB (cimetidine).
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ACE inhibitors, or angiotensin-converting enzyme inhibitors, include lisinopril (Zestril), benazepril (Lotensin) and enalapril (Vasotec). ARBs, or angiotensin-receptor blockers, include losartan (Cozaar), valsartan (Diovan) and irbesartan (Avapro).
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Clopidogrel belongs to a group of medicines known as antiplatelet medicines. Platelets are very small blood cells which clump together during blood clotting. By preventing this clumping, antiplatelet medicines reduce the chances of blood clots forming (a process called thrombosis).
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Ticagrelor has more remarkable beneficial outcomes in reversible long-term P2Y12 inhibition than clopidogrel in the total death, cardiovascular prevention, stent thrombosis as well as myocardial infarction without increasing the major bleeding rates in a wide ACS patient population with timely intervention, according ...
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Plavix (clopidogrel bisulfate) is an anti-platelet drug used to prevent blood clots. Plavix is used to reduce the risk of heart attacks and strokes, particularly in people with a recent history of stroke or heart attack, and those with peripheral vascular disease.
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ACE inhibitors are popular drugs for high blood pressure and heart failure. Because ACE inhibitors are metabolized by the kidneys, they do come with a risk of causing kidney damage, especially if you are dehydrated, which is often the case in people with existing kidney problems—like chronic kidney disease.
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['ACE inhibitors.', 'renin inhibitors.', 'angiotensin receptor blockers.']
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Accupril (quinapril) is an angiotensin converting enzyme (ACE) inhibitor used for treating high blood pressure and heart failure.
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1). Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.
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Lisinopril is a type of medicine called an angiotensin-converting enzyme (ACE) inhibitor. Like other ACE inhibitors, lisinopril relaxes and widens the blood vessels. This lowers your blood pressure and makes it easier for your heart to pump blood around your body. This can improve the symptoms of heart failure.
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Evidence-Based Answer. ACE inhibitors should be used in patients with hypertension because they reduce all-cause mortality, whereas ARBs do not. (Strength of Recommendation [SOR]: A, based on a meta-analysis.) ARBs are preferred for patients who have adverse reactions to ACE inhibitors.
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Angiotensin-converting-enzyme (ACE) inhibitors (blood pressure medication) may induce a cough or excessive throat clearing in as many as 10 percent of patients.
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7 Days Prior To Your Procedure: Stop taking all anti-platelet medications: Plavix (clopidogrel), Pletal, Ticlid (ticlopidine), Aggrenox, Agrylin (anagrelide), or Effient. 5 Days Prior To Your Procedure: Stop taking Coumadin (warfarin) and Jantoven.