will synthroid cause weight loss?
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Summary: Contrary to popular belief, effective treatment with levothyroxine (LT4) to restore normal thyroid hormone levels is not associated with clinically significant weight loss in most people. Decreased thyroid function, or hypothyroidism, is commonly associated with weight gain.
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It's also possible for you to gain weight if your dose of Synthroid isn't high enough for your body's needs. This is because if your thyroid hormone levels aren't high enough, your metabolism* may be slowed.
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Even mild cases of hypothyroidism may increase the risk of weight gain and obesity. People with the condition often report having a puffy face as well as excess weight around the stomach or other areas of the body.
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Notify your doctor if you experience serious side effects of Synthroid including rapid heartbeat, fluttering in your chest, or chest pain.
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Thyroid disease can affect a person's weight by regulating how fast they burn calories, or how slow they burn calories. It all works toward speeding up if it's overactive, or under active, it can slow everything down, so it makes them gain weight uncontrollably.
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According to Dr. Kitahara, if someone has low thyroid function, their TSH is high, and the thyroid hormones known as T3 and T4 are low—and weight gain often occurs. If someone has an overactive thyroid or hyperthyroidism, TSH is usually low, the T3 and T4 are high, and weight loss occurs.
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Although certain factors like pregnancy or other medications (estrogen, birth control pills, or certain antidepressants) affect your need for thyroid hormone, the dose usually remains fairly stable over time. Most people who take enough synthetic T4 to normalize TSH levels will find that their symptoms go away.
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The thyroid produces certain hormones that regulate the body's metabolism, so an excess of these hormones often causes the body to burn more energy than usual. Burning more energy and calories can lead to unintentional or unexplained weight loss. Other symptoms of hyperthyroidism include: fatigue.
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Following thyroid surgery, patients often complain of weight gain, even when they have achieved biochemical euthyroidism. Studies examining this issue have found mixed results. Many of these studies have unclear/incomplete follow-up and are at high risk of selection bias (6–9).
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Hyperthyroidism (overactive thyroid) occurs when your thyroid gland produces too much of the hormone thyroxine. Hyperthyroidism can accelerate your body's metabolism, causing unintentional weight loss and a rapid or irregular heartbeat. Several treatments are available for hyperthyroidism.
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If your thyroid is underactive, a lack of treatment, or insufficient treatment, may make weight loss almost impossible, despite diet and exercise. And the longer it takes you to get diagnosed, the more weight you could gain.
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Symptom: Weight Gain or Loss Weight gain may signal low levels of thyroid hormones, a condition called hypothyroidism. In contrast, if the thyroid produces more hormones than the body needs, you may lose weight unexpectedly. This is known as hyperthyroidism. Hypothyroidism is far more common.
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The link between hypothyroidism and weight gain Weight gain or the inability to lose weight is a common concern for people with hypothyroidism. Even when on treatment, there is usually only a modest loss in weight.
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In 2013, a study published in the Journal of Reproductive Biology and Endocrinology established a correlative link between Synthroid usage and lung cancer risk. The study initially states that Levothyroxine usage can cause oxidative stress, and this is a known driver of cancer growth.
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While the symptoms that accompany hypothyroidism (an underactive thyroid), can disrupt several parts of your life, weight gain seems to be one area that causes significant distress and frustration. When your thyroid is underactive, your metabolism slows down, which can lead to weight gain.
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Generic levothyroxine may differ slightly from Synthroid in terms of how well it's absorbed. That's why it's preferable to stick with either one if possible. Both the American Thyroid Association and the Endocrine Society recommend that patients remain on Synthroid if that's what was initially prescribed.
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In all these effects note that progesterone does not directly cause weight loss. Instead it reduces the effect of other hormones in the body which are causing the weight gain. Think of it as allowing rather than causing the body to lose weight.