ataxin 1 what is it?
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Ataxin-1 is a DNA-binding protein which in humans is encoded by the ATXN1 gene. Mutations in ataxin-1 cause spinocerebellar ataxia type 1, an inherited neurodegenerative disease characterized by a progressive loss of cerebellar neurons, particularly Purkinje neurons.
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Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, adenosine triphosphate (ATP).
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The HTT mutation that causes Huntington disease involves a DNA segment known as a CAG trinucleotide repeat. This segment is made up of a series of three DNA building blocks (cytosine, adenine, and guanine) that appear multiple times in a row. Normally, the CAG segment is repeated 10 to 35 times within the gene.
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Anavex-2-73 is a small molecule that targets a protein receptor called the sigma-1 receptor, which is a so-called chaperone that guides newly synthesized proteins through a compartment in the cell called the endoplasmic reticulum, ensuring that proteins fold correctly as they are made.
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Hydroxyzine (brand names: Atarax®, Vistaril®, Masmoran®, Multipax®) is an antihistamine used to treat allergic and itchy conditions or as a sedative/tranquilizer. Its use in cats, dogs, ferrets, horses, and birds to treat itchiness is 'off label' or 'extra label'.
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Alpha-1 antitrypsin deficiency (AAT deficiency) is an inherited condition that raises your risk for lung and liver disease. Alpha-1 antitrypsin (AAT) is a protein that protects the lungs. The liver makes it. If the AAT proteins aren't the right shape, they get stuck in the liver cells and can't reach the lungs.
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Gangliosidosis-1 (GM-1) is a progressive neurological genetic disorder caused by the absence of a vital enzyme. It is one of over 50 genetically inherited disorders known as Lysosomal Storage Diseases.
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Apraxia results in a person's inability to carry out a familiar purposeful movement, while in ataxia they can carry out the movement with little coordination. Remember, this is a generalization and is not applicable to all forms of ataxia versus the different forms of apraxia.
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A positive Romberg test suggests that the ataxia is sensory in nature, that is, depending on loss of proprioception. If a patient is ataxic and Romberg's test is not positive, it suggests that ataxia is cerebellar in nature, that is, depending on localized cerebellar dysfunction instead.
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Myotonic dystrophy type 1 (DM1) is a multisystem disorder that affects skeletal and smooth muscle as well as the eye, heart, endocrine system, and central nervous system.
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['mRNA codon: GCU. ... ', 'mRNA codon: ACA. ... ', 'DNA base triplet: CTT. ... ', 'Based on the information in the answers to the question above, what is one anticodon for a tRNA that carries glutamate?', 'Which of the following is NOT true of anticodons? ... ', 'Which of the following sequences is complementary to: GCUCGU.']
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Glutaric acidemia type I (also called glutaric aciduria type I) is an inherited disorder in which the body is unable to process certain proteins properly. It is classified as an organic acid disorder, which is a condition that leads to an abnormal buildup of particular acids known as organic acids.
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Atad is an Old Testament Hebrew name meaning buckthorn. Atad was the place where Joseph and his brothers, when on their way from Egypt to Hebron with the remains of their father Jacob, made for seven days a "great and very sore lamentation". On this account the Canaanites called it "Abel-mizraim" (Genesis 50:10-11).
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If your dog suddenly loses their sense of balance they could be suffering from a serious health problem that requires immediate veterinary attention. Ataxia in dogs is the name given to the condition relating to a sensory dysfunction that results in a loss of coordination in the dog's head, limbs, or rear end.
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ATG or AUG. The codon for Methionine; the translation initiation codon. Usually, protein translation can only start at a Methionine codon (although this codon may be found elsewhere within the protein sequence as well). In eukaryotic DNA, the sequence is ATG; in RNA it is AUG.
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Atarax belongs to a group of medicines called antihistamines (used to treat allergic reactions). It is used in adults and children to reduce itching caused by urticaria (nettle rash) and dermatitis (eczema). Atarax is also used to treat anxiety in adults.
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Polysaccharide Storage Myopathy, Type 1. Polysaccharide Storage Myopathy (PSSM) is an inherited muscle disease that affects many and diverse breeds of horses. ... This mutation results in the accumulation of abnormal complex sugars within skeletal muscle of horses. This form of PSSM is termed Type 1 PSSM.