what are serious side effects and drug interactions of nsaids?
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['Stomach pain and heartburn.', 'Stomach ulcers.', 'A tendency to bleed more, especially when taking aspirin. ... ', 'Headaches and dizziness.', 'Ringing in the ears.', 'Allergic reactions such as rashes, wheezing, and throat swelling.', 'Liver or kidney problems. ... ', 'High blood pressure.']
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The longer you take NSAIDs, the more your potential for heart problems goes up. Stomach—People who take NSAIDs regularly are more likely to develop upset stomach symptoms, and potentially ulcers and bleeding in the gastrointestinal (GI) tract.
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The most commonly occurring (≥5%) adverse events in celecoxib treated patients were headache, fever (pyrexia), upper abdominal pain, cough, nasopharyngitis, abdominal pain, nausea, arthralgia, diarrhea and vomiting.
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Don't take anti-inflammatory painkillers (NSAIDs) like aspirin, ibuprofen or naproxen while you're taking prednisolone, unless they've been prescribed by your doctor. This type of painkiller may increase the risk of side effects on the gut, such as stomach ulceration and bleeding.
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The more common side effects of ibuprofen are: stomach pain. heartburn. nausea.
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Like any drug, if ibuprofen is taken in higher than recommended doses, it can harm your health. Overuse of ibuprofen can seriously damage your digestive system, interfere with your hormones, and increase your risk of heart attacks and stroke. In some cases, ibuprofen overdose can be deadly.
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Since the medication in diclofenac topical may be absorbed from the skin, combining it with ibuprofen may increase the risk and/or severity of side effects reported with this class of drugs, including stomach ulcer, fluid retention, high blood pressure, bleeding, and liver or kidney problems.
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['Heart—NSAIDs have been linked to a greater risk for heart attacks, strokes, and heart-related deaths. ... ', 'Stomach—People who take NSAIDs regularly are more likely to develop upset stomach symptoms, and potentially ulcers and bleeding in the gastrointestinal (GI) tract.']
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['NSAIDs relieve fever and pain. ... ', 'When taken for a short time (no longer than 10 days), NSAIDs are safe for most people.', 'Some NSAIDs can be bought over the counter, such as aspirin, ibuprofen (Advil, Motrin), and naproxen (Aleve, Naprosyn).', 'Other NSAIDs are prescribed by your provider.']
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Except for aspirin, all over-the-counter NSAIDs now must carry a warning about the risks of heart attack and stroke along with other side effects. NSAIDs have other dangers, too. They can cause high blood pressure and kidney damage in some people. They can also cause potentially severe allergic reactions.
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Recreational use of diclofenac It is not possible to get high off of diclofenac or other NSAIDs, and abuse of the drug is likely to cause serious side effects.
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Using ibuprofen together with etodolac is generally not recommended. Combining these medications may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.
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Loxicom Precautions. Serious side effects have been reported with meloxicam including: Cardiovascular thrombotic events. Meloxicam can increase your risk of cardiovascular and heart diseases such as strokes and myocardial infarctions, which can lead to death.
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Although relatively safe in humans, ibuprofen and other NSAIDs can be extremely harmful to dogs. Ibuprofen poisoning is very common, and even small doses can cause adverse effects and poisoning.
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Alcohol can also irritate the stomach and digestive tract. Mixing the two further increases the risk of ulcers and bleeding. The National Institutes of Health (NIH) state that ibuprofen can interact with alcohol, which can worsen the usual side effects of ibuprofen.
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ibuprofen methylPREDNISolone Using methylPREDNISolone together with ibuprofen may increase the risk of side effects in the gastrointestinal tract such as inflammation, bleeding, ulceration, and rarely, perforation.
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Tell your doctor right away if you have any serious side effects, including: easy bruising/bleeding, persistent/severe headache, mental/mood changes, sudden/unexplained weight gain, swelling of the hands/feet, change in the amount of urine, unexplained stiff neck, unusual tiredness.