what are risk factors for type 1 diabetes?
347022
['Family history. Anyone with a parent or sibling with type 1 diabetes has a slightly increased risk of developing the condition.', 'Genetics. The presence of certain genes indicates an increased risk of developing type 1 diabetes.', 'Geography. ... ', 'Age.']
484691
In type 1 diabetes, there's no insulin to let glucose into the cells, so sugar builds up in your bloodstream. This can cause life-threatening complications.
632245
Risk of diabetes type 1 'can be tripled by childhood stress' Stressful life events in childhood such as family break-up, death or illness, can triple the risk of developing type 1 diabetes, research suggests.
892032
In type 1 diabetes, high HbA1c levels increase the risk of complications such as retinopathy (damage to the blood vessels supplying the retina) and kidney disease, therefore people with type 1 diabetes are recommended to aim for an HbA1c of 6.5% or lower.
106290
Emerging evidence suggests that obesity contributes to insulin resistance, dyslipidemia, and cardiometabolic complications in type 1 diabetes. Unique therapeutic strategies may be required to address these comorbidities within the context of intensive insulin therapy, which promotes weight gain.
1018151
['diabetes (usually only type 1 diabetes)', 'spinal cord injuries.', 'multiple sclerosis.', 'surgery to the bladder or prostate gland.', 'increasing age.']
155863
Type 1 diabetes (T1D) is a chronic disease caused by immune-mediated destruction of insulin producing beta cells in the pancreas[1]. The destruction of beta cells results in insulin insufficiency, and patients develop life-threatening hyperglycemia that clinically manifests with weight loss, polyuria, and polydipsia.
803653
Type 1 diabetes linked to pancreatic cancer risk. NEW YORK (Reuters Health) - It is well known that people with type 2 diabetes are at increased risk of pancreatic cancer, and now it seems that the risk extends to those with type 1 diabetes, researchers report. However, they point out that the risk is still very small.
350694
The causes of type 1 diabetes are unknown, although several risk factors have been identified. The risk of developing type 1 diabetes is increased by certain variants of the HLA-DQA1, HLA-DQB1, and HLA-DRB1 genes. These genes provide instructions for making proteins that play a critical role in the immune system.
387698
A series of studies have reported a constant global rise in the incidence of type 1 diabetes. Epidemiological and immunological studies have demonstrated that environmental factors may influence the pathogenesis, leading to a cell-mediated pancreatic β-cell destruction associated with humoral immunity.
321206
Different factors, including genetics and some viruses, may contribute to type 1 diabetes. Although type 1 diabetes usually appears during childhood or adolescence, it can develop in adults.
1344189
Type 1 diabetes is what is known as a 'complex trait', which means that mutations in several genes likely contribute to the disease. For example, it is now known that the insulin-dependent diabetes mellitus (IDDM1) locus on chromosome 6 may harbor at least one susceptibility gene for Type 1 diabetes.
22423
A healthy diet Apart from managing blood glucose levels with insulin and carbohydrates, people with Type 1 diabetes are also encouraged to make healthier food choices that are lower in saturated fat, sugar and salt. Doing these will help to: control blood fats. control blood pressure.
1454517
['Diet.', 'Smoking.', 'Alcohol use.', 'Sedentary lifestyle.', 'Obesity.', 'Diabetes.']
310976
['Weight. Being overweight is a primary risk factor for prediabetes. ... ', 'Waist size. A large waist size can indicate insulin resistance. ... ', 'Diet. ... ', 'Inactivity. ... ', 'Age. ... ', 'Family history. ... ', 'Race. ... ', 'Gestational diabetes.']
1339892
This form is typically caused by an autoimmune disorder, meaning that the body's immune system mistakenly attacks cells that make insulin. In some people, type 1 diabetes may occur after a viral infection, such as cytomegalovirus, encephalitis, Epstein-Barr virus, influenza, measles, mumps, polio, or rubella.
1398410
T1D Facts. Type 1 diabetes (T1D) is an autoimmune disease that progresses in three stages. In people with T1D, the immune system mistakenly attacks and destroys healthy insulin producing cells, called beta cells. TrialNet is working to change that.