can down syndrome males reproduce?
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While females with Down syndrome are reported to be fertile or subfertile, males are reported to be infertile. To date, there are reports of three pregnancies that were fathered by two male Down syndrome patients (1, 2). We report a case of a nonmosaic Down syndrome male who fathered a normal child.
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In most cases of Down syndrome, a child gets an extra chromosome 21 — for a total of 47 chromosomes instead of 46. It's this extra genetic material that causes the physical features and developmental delays associated with DS.
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Also known as Down syndrome, trisomy 21 is a genetic condition caused by an extra chromosome. Most babies inherit 23 chromosomes from each parent, for a total of 46 chromosomes. Babies with Down syndrome however, end up with three chromosomes at position 21, instead of the usual pair.
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In humans, meiosis is the process by which sperm cells and egg cells are produced. In the male, meiosis takes place after puberty. Diploid cells within the testes undergo meiosis to produce haploid sperm cells with 23 chromosomes. A single diploid cell yields four haploid sperm cells through meiosis.
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A 25-year-old woman has a 1 in 1,200 chance of having a baby with Down syndrome; by 35, the risk has increased to 1 in 350; by age 40, to 1 in 100; and by 49, it's 1 in 10, according to the National Down Syndrome Society.
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Normally, at the time of conception a baby inherits genetic information from its parents in the form of 46 chromosomes: 23 from the mother and 23 from the father. In most cases of Down syndrome, a child gets an extra chromosome 21 — for a total of 47 chromosomes instead of 46.
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Risk factors include: Advancing maternal age. A woman's chances of giving birth to a child with Down syndrome increase with age because older eggs have a greater risk of improper chromosome division. A woman's risk of conceiving a child with Down syndrome increases after 35 years of age.
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Most people have 46 chromosomes in each of their cells. People with Down syndrome have 47, and because of that they may look and learn differently.
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Typically, a baby is born with 46 chromosomes. Babies with Down syndrome have an extra copy of one of these chromosomes, chromosome 21. A medical term for having an extra copy of a chromosome is 'trisomy. ' Down syndrome is also referred to as Trisomy 21.
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There are three types of Down syndrome. People often can't tell the difference between each type without looking at the chromosomes because the physical features and behaviors are similar. Trisomy 21: About 95% of people with Down syndrome have Trisomy 21.
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Normally, meiosis causes each parent to give 23 chromosomes to a pregnancy. When a sperm fertilizes an egg, the union leads to a baby with 46 chromosomes. But if meiosis doesn't happen normally, a baby may have an extra chromosome (trisomy), or have a missing chromosome (monosomy).
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It was described in the 19th century, but has probably existed throughout human history. However there are few cases of Down's syndrome in the archaeological record. The new example comes from a 5th- and 6th-century necropolis near a church in Chalon-sur-Saône in eastern France.
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The ability of Y-chromosome sperm to swim faster than their X-chromosome counterparts may explain why longer attempts at pregnancy result in more boys than girls.
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Like anyone else, if a person with Down syndrome is able to pass the written and practical tests, they are allowed to drive. With practice and help, people with Down syndrome are able to do many of the things that all people are able to do.
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Women with Down syndrome are able to have children, but many men with the condition unfortunately are not able to, however it is possible. Women who have Down syndrome are able to have children; they have a 35-50% chance that their baby will have Down syndrome.
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The egg from its mother always contains an X (female) chromosome, but the sperm contains either a female or a Y (male) chromosome. When the egg is fertilised the chromosomes come together and if they are XY a baby boy is conceived and if they are XX a baby girl is conceived.
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Many men with 47,XYY karyotype are fertile in spite of their sex chromosome abnormalities. Some researchers have suggested that the extra Y chromosome is lost before meiosis,3,6–8 thus conserving fertility in these patients.