what parts of the brain are affected by lewy body dementia?
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['The cerebral cortex, which controls many functions, including information processing, perception, thought, and language.', 'The limbic cortex, which plays a major role in emotions and behavior.']
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When dementia with Lewy bodies is caused by SNCA or SNCB gene mutations, it is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder. In these cases, an affected person usually has one parent with the condition.
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About 1.3 million Americans have the disease, which is caused by protein deposits in the brain. Williams was diagnosed with Parkinson's disease a few months before he died; the telltale signs of Lewy body dementia in his brain were not discovered until an autopsy.
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Symptoms of dementia include progressive difficulty with: Memory, such as forgetting names of family members or regressing to childhood memories. Communication and language, such as forgetting the word for everyday items. Ability to focus and pay attention, such as “spacing out” or an inability to complete tasks.
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At the level of the brain, Parkinson's dementia is thought to be related to Lewy bodies (sticky clumps of protein found in nerve cells of people with Parkinson's). Most people with Parkinson's develop dementia as a progression of their Parkinson's disease, rather than having both Parkinson's and Alzheimer's.
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Is dementia a mental illness? No, it is a condition of the brain. Our brain is our control centre and it controls everything we do and say and think. When the brain is sick we have problems with all our actions, including remembering, speaking, understanding and learning new skills.
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Summary: Medical researchers demonstrate that ALS -- known as Lou Gehrig's disease -- damages neurons in parts of the brain responsible for cognition and behavior. The scientists provide evidence that ALS affects more than just the motor cortex, the part of the brain responsible for motor function.
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While most changes in the brain that cause dementia are permanent and worsen over time, thinking and memory problems caused by the following conditions may improve when the condition is treated or addressed: Depression. Medication side effects. Excess use of alcohol.
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At first, Alzheimer's disease typically destroys neurons and their connections in parts of the brain involved in memory, including the entorhinal cortex and hippocampus. It later affects areas in the cerebral cortex responsible for language, reasoning, and social behavior.
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In these ways, the symptoms of Parkinson's disease dementia are similar to LBD and the main difference is in timing. In Lewy body dementia, memory and thinking changes typically come on early in the disease, at the same time or within a year of the movement symptoms.
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Some Lewy body dementia symptoms may respond to treatment for a period of time. Currently, there is no cure for the disease. Research is improving our understanding of this challenging condition, and advances in science may one day lead to better diagnosis, improved care, and new treatments.
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The biggest part of the brain is the cerebrum. The cerebrum is the thinking part of the brain and it controls your voluntary muscles — the ones that move when you want them to. So you need your cerebrum to dance or kick a soccer ball.
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Mania can be a symptom in all types of dementia, but it's more commonly seen in frontal lobe dementia and Lewy body dementia. Both diseases can cause agitation, hyperactivity, inappropriate social behavior, and other symptoms often associated with mania.
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["Alzheimer's disease. Alzheimer's disease affects brain function, memory and behaviour. ... ", "Bell's palsy. Bell's palsy is a sudden weakness or paralysis of facial muscles on one side of the face. ... ", 'Cerebral palsy. ... ', 'Epilepsy. ... ', 'Motor neurone disease (MND) ... ', 'Multiple sclerosis (MS) ... ', 'Neurofibromatosis. ... ', "Parkinson's disease."]
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Dementia is an overall term used to describe symptoms that impact memory, performance of daily activities, and communication abilities. Alzheimer's disease is the most common type of dementia. Alzheimer's disease gets worse with time and affects memory, language, and thought.
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Genetics—While having a family member with LBD may increase a person's risk, LBD is not normally considered a genetic disease. Variants in three genes—APOE, SNCA, and GBA—have been associated with an increased risk of dementia with Lewy bodies, but in most cases, the cause is unknown.
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This type of dementia is diagnosed by taking a careful history of the pattern of symptoms, and by excluding other possible causes such as Vascular dementia and Alzheimer's disease. A brain scan may reveal brain degeneration, but the Lewy bodies can only be identified by examination of brain tissue after death.