can duloxetine cause weight gain?
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Share on Pinterest Studies have found that Cymbalta is more likely to cause weight loss, rather than weight gain. Most related research suggests that Cymbalta can affect a person's weight, but only modestly.
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Taking duloxetine with certain other drugs can affect serotonin levels, blood pressure and body temperature. It can lead to a life-threatening condition called serotonin syndrome. Symptoms of serotonin syndrome can include agitation, confusion, diarrhea and dilated pupils.
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Increased blood pressure and heart rate have been reported in duloxetine trials. The proposed mechanism for duloxetine-induced tachycardia is its effects on norepinephrine, which impact the cardiovascular system.
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Duloxetine may cause some people to become dizzy or have blurred vision. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are not alert or able to see clearly.
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Missing doses of duloxetine may increase your risk for relapse in your symptoms. Stopping duloxetine abruptly may result in one or more of the following withdrawal symptoms: irritability, nausea, feeling dizzy, vomiting, nightmares, headache, and/or paresthesias (prickling, tingling sensation on the skin).
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While scientists and doctors have long known that antidepressants can cause weight gain, there isn't a huge amount of evidence showing why this happens. In general, there doesn't appear to be a lot of evidence that sertraline and other SSRIs have a direct effect on your metabolism.
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Using cyclobenzaprine together with DULoxetine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred ...
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There has been little systematic long-term data regarding weight effects of SSRI antidepressants (which include fluoxetine (Prozac), sertraline (Zoloft), citalopram (Celexa), escitalopram (Lexapro), paroxetine (Paxil), and fluvoxamine (Luvox), and the SNRIs venlafaxine (Effexor) and duloxetine (Cymbalta), although some ...
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While some people gain weight after starting an antidepressant, the antidepressant isn't always a direct cause. Many factors can contribute to weight gain during antidepressant therapy. For example: Overeating or inactivity as a result of depression can cause weight gain.
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A reported side effect of Cymbalta is weight changes — typically weight loss due to decreased appetite. In clinical studies, however, weight gain was reported in some people taking Cymbalta. Talk to your health care provider if this side effect persists and becomes bothersome.
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Compared to citalopram, the weight gain linked to other antidepressants was small. Bupropion was associated with the least amount of weight gain, close to none. Two others that also appeared to have less weight gain were amitriptyline and nortriptyline. Amitriptyline and nortriptyline are older drugs.
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Duloxetine was given between 60 and 120 mg daily over 8 weeks. Results: Duloxetine led to a significant improvement of PTSD-characteristic symptoms as well as co-morbid MDD. Duloxetine effectively reduced nightmares, which is important because decreasing nightmares has been associated with improved sleep in PTSD.
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If you do, you may develop confusion, agitation, restlessness, stomach or intestinal symptoms, sudden high body temperature, extremely high blood pressure, or severe convulsions. Duloxetine may cause some teenagers and young adults to be agitated, irritable, or display other abnormal behaviors.
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Zoloft and Weight Gain Weight gain caused by Zoloft may be due to fluid retention, lack of exercise, increased appetite, or other factors. Experts recommend physical activity and eating fewer high-calorie foods to manage weight gain while taking Zoloft or other antidepressants.
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Duloxetine-induced liver injury in patients with preexisting liver disease or chronic alcohol use is known. However, we have found that duloxetine can also induce liver injury in cases without those risk factors. We recommend that clinicians should monitor liver function carefully following duloxetine treatment.
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Common side effects include feeling sick, a dry mouth, headache, constipation and feeling sleepy. These side effects are usually mild and go away after a couple of weeks. If you and your doctor decide to take you off duloxetine, your doctor may recommend reducing your dose gradually to help prevent extra side effects.
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Celexa has been associated with slight weight gain, but it's thought that the drug itself doesn't cause this effect. Rather, the weight increase is likely due to improved appetite from taking the drug. A better appetite can cause you to eat more, leading to increased body weight.