is duloxetine safe in pregnancy?
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It's important for you and your baby that you stay well during your pregnancy. There's no firm evidence that duloxetine is harmful to an unborn baby. But for safety, pregnant women are usually advised to only take it if the benefits of the medicine outweigh the potential risks.
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Which antidepressants are considered OK during pregnancy? Generally, these antidepressants are an option during pregnancy: Certain selective serotonin reuptake inhibitors (SSRIs). SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Zoloft).
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A meta- analysis of forty-two placebo-controlled trials on individuals treated with Duloxetine showed a statistically significant increase in palpitations, tachycardia and hypertension [21].
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Pregnancy and breastfeeding If you become pregnant while taking escitalopram, speak to your doctor. Do not stop taking your medicine unless your doctor tells you to. Escitalopram has been linked to a very small increased risk of problems for your unborn baby.
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Duloxetine is a balanced serotonin-norepinephrine reuptake inhibitor. Duloxetine-induced liver injury in patients with preexisting liver disease or chronic alcohol use is known. However, we have found that duloxetine can also induce liver injury in cases without those risk factors.
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Low blood pressure, falls, and passing out have happened with Cymbalta (duloxetine capsules). Falls may lead to problems like broken bones and the need to go to the hospital.
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Taking duloxetine with certain other drugs can affect serotonin levels, blood pressure and body temperature. It can lead to a life-threatening condition called serotonin syndrome. Symptoms of serotonin syndrome can include agitation, confusion, diarrhea and dilated pupils.
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The ingestion of high quantities of Duloxetine may have serious outcomes such as venous thrombosis, causing cardiac respiratory arrest.
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Dr. Schaffir says that other antihistamines, such as promethazine, are also safe during pregnancy. The prescription drug promethazine is sometimes used to treat nausea and vomiting (and it's also prescribed for allergies, motion sickness, and sleep regulation).
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SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Zoloft).
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There are no large studies looking at the chance of birth defects when escitalopram is used during pregnancy. Since it is very similar to citalopram, escitalopram is also unlikely to increase the chance of birth defects over the background risk.
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Generally, these antidepressants are an option during pregnancy: Certain selective serotonin reuptake inhibitors (SSRIs). SSRIs are generally considered an option during pregnancy, including citalopram (Celexa) and sertraline (Zoloft). Potential complications include maternal weight changes and premature birth.
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Duloxetine-induced liver injury in patients with preexisting liver disease or chronic alcohol use is known. However, we have found that duloxetine can also induce liver injury in cases without those risk factors. We recommend that clinicians should monitor liver function carefully following duloxetine treatment.
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Duloxetine does not seem to be associated with objective acute urinary retention in men and women treated for MDD or in women treated for SUI. A small but significant number of men and women did report some obstructive voiding symptoms when treated with duloxetine.
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If you are pregnant and have taken ondansetron or Zofran® during pregnancy, I want to reassure you that it likely has not affected your baby. Even if the increased risk for cleft palate or heart defects turns out to be true, the risk to your baby is still very, very small.
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Uses. Duloxetine is used to treat depression and anxiety. In addition, duloxetine is used to help relieve nerve pain (peripheral neuropathy) in people with diabetes or ongoing pain due to medical conditions such as arthritis, chronic back pain, or fibromyalgia (a condition that causes widespread pain).
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About duloxetine Duloxetine is an antidepressant medicine. It's used to treat depression and anxiety. It's also used to treat nerve pain, such as fibromyalgia, and can be used to treat stress urinary incontinence in women. Duloxetine comes as capsules and is only available on prescription.