where are bile salts synthesized and secreted?
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Bile salts are synthesized and conjugated in the liver; secreted into bile; stored temporarily in the gallbladder; passed from the gallbladder into the duodenum; absorbed throughout the small intestine, especially in the ileum; and returned to the liver via the portal vein.
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Lecithins are phospholipids that are used to make bile. Chylomicrons are lipoproteins produced in the enterocyte that carry fats and cholesterol from the intestine through the lymph system and to the bloodstream. Take a bite of pizza.
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About the bile ducts The bile ducts are a series of thin tubes that go from the liver to the small intestine. Their major job is to move a fluid called bile from the liver and gallbladder into the small intestine, where it helps digest the fats in food.
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The small intestine contains all the enzymes that has been secreted by the pancreas and the liver. These may include: nuclease, pancreatic amylase, lipase, trypsin, bile (which is actually salt), and some bicarbonates (agai...
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Bile reflux occurs when bile — a digestive liquid produced in your liver — backs up (refluxes) into your stomach and, in some cases, into the tube that connects your mouth and stomach (esophagus). Bile reflux may accompany the reflux (backwash) of stomach acid (gastric acid) into your esophagus.
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About the bile ducts The bile ducts are a series of thin tubes that go from the liver to the small intestine. Their major job is to move a fluid called bile from the liver and gallbladder into the small intestine, where it helps digest the fats in food. Different parts of the bile duct system have different names.
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['Mostly cholesterol.', 'Bile acids (also called bile salts)', 'Bilirubin (a breakdown product or red blood cells)']
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Bile acids are steroid acids found predominantly in the bile of mammals and other vertebrates. Diverse bile acids are synthesized in the liver. Bile acids are conjugated with taurine or glycine residues to give anions called bile salts. Primary bile acids are those synthesized by the liver.
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The gallbladder stores bile, which it then secretes into the small intestine. Bile contributes to digestion by breaking up large fat globules, a process known as emulsification. Fats are insoluble in water, so emulsification provides pancreatic lipase with more surface area on which to act.
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Lipids (fats and oils) Digestion of fat in the small intestine is helped by bile, made in the liver. Bile breaks the fat into small droplets that are easier for the lipase enzymes to work on. Bile is not an enzyme.
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Lipids are hydrophobic substances. Bile contains bile salts, which have hydrophobic and hydrophilic sides. The bile salts' hydrophilic side can interface with water, while the hydrophobic side interfaces with lipids, thereby emulsifying large lipid globules into small lipid globules.
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Ursodeoxycholic acid, also known as ursodiol, is one of the acids found in bear bile that is truly medically effective for treating certain liver diseases and gallstones. It has been produced synthetically since the 1950s and is manufactured by major pharmaceutical companies.
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Lipids, or fat, go undigested in your digestive tract until they reach your small intestine, where they meet bile. Bile contains bile salts, which act as an emulsifier of lipids. This breaks the large fat droplets into smaller droplets that are then easier for the fat-digesting enzyme pancreatic lipase to digest.
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Introduction. Pancreatic acinar cells synthesize and secrete almost all the digestive enzymes active in the lumen of the small intestine which are necessary for nutrient digestion. Both synthesis and secretion are highly regulated over both short and long time frames to insure an appropriate supply of digestive enzymes ...
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Calculi of the gallbladder and bile ducts are called gallstones and are primarily developed from bile salts and cholesterol derivatives. Calculi in the nasal passages (rhinoliths) are rare. Calculi in the gastrointestinal tract (enteroliths) can be enormous.
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INTRODUCTION. Altered serum bile acids concentration has been known to occur in patients with liver diseases. 1–13) Bile acids are formed in the liver from cholesterol, excreted via bile into the intestine, where they are reabsorbed into portal circulation and returned to the liver.
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The pKa of the unconjugated bile acids are between 5 and 6.5, and the pH of the duodenum ranges between 3 and 5, so when unconjugated bile acids are in the duodenum, they are almost always protonated (HA form), which makes them relatively insoluble in water.