what are follicular dendritic cells?
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Follicular dendritic cells. Definition. Follicular dendritic cells (FDCs) are non-haematopoietic cells that are present in the B cell follicles of secondary lymphoid tissues.
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At puberty and throughout a woman's life, a subset of these follicles undergo maturation under the influence of hormones, including follicle stimulating hormone (FSH), via the hypothalamic–pituitary–ovarian axis. Development occurs through the primary, secondary (preantral), tertiary (antral), and preovulatory ( ...
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Dendritic cells have been shown to have a role in T-cell and B-cell functions, including proliferation and antibody isotype switching. ... CD40 expression on DC and B cells is well established and it has been assumed that these cells then interact with CD40 ligand (CD40L) on activated T cells.
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The follicle is a fluid filled sac that houses the egg, and the corpus luteum is the structure left behind after the egg bursts from the follicle (or ovulation).
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['Follicular unit excision (FUE)', 'Follicular unit transplantation (FUT)']
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The rise in follicle stimulating hormone stimulates the growth of the follicle in the ovary. With this growth, the cells of the follicles produce increasing amounts of oestradiol and inhibin.
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In the ovaries of the female reproductive system, an ovarian follicle is a fluid-filled sac that contains an immature egg, or oocyte. These follicles are found in the ovaries. During ovulation, a mature egg is released from a follicle.
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Dendritic cells have been shown to have a role in T-cell and B-cell functions, including proliferation and antibody isotype switching. However, the molecules involved in these interactions are unknown. ... Moreover, CD40 has been shown to have a role in B-cell survival12 but it was assumed to be via T cells.
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Nonspecific immune cell. A non-specific immune cell is an immune cell (such as a macrophage, neutrophil, or dendritic cell) that responds to many antigens, not just one antigen. Non-specific immune cells function in the first line of defense against infection or injury.
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Like macrophages and neutrophils, dendritic cells (DCs) are considered professional phagocytes. Even if the three cell types phagocytose parasites, bacteria, cell debris, or even intact cells very efficiently, the functional outcomes of the phagocytic event are quite different.
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Professional APCs include macrophages, dendritic cells, and b-cells. They're 'professional' as they all express Class II MHC. Non-professional APCs do not express Class II MHC unless stimulated by certain cytokines.
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Dendrites are tree-like extensions at the beginning of a neuron that help increase the surface area of the cell body. These tiny protrusions receive information from other neurons and transmit electrical stimulation to the soma. Dendrites are also covered with synapses.
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The Graafian follicle is the stage after the first meiotic division has completed but before ovulation. ... The follicle is characterized by a large follicular antrum that makes up most of the follicle. The secondary oocyte, having undergone the first meiotic division, is located eccentrically.
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During and after puberty these follicles develop and are released on a monthly basis. An antral follicle is a resting follicle and appears as a small fluid-filled sac which contains an immature egg. These follicles can be measured and counted on cycle days 2, 3 and 5. The antral follicles vary every month.
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MHC class II can be conditionally expressed by all cell types, but normally occurs only on "professional" antigen-presenting cells (APCs): macrophages, B cells, and especially dendritic cells (DCs).
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Dendrites and axons are cytoplasmic extensions, or processes, that project from the cell body. They are sometimes referred to as fibers. Dendrites are usually, but not always, short and branching, which increases their surface area to receive signals from other neurons.
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Dendritic cells are the most efficient antigen-presenting cells. They take up antigens and pathogens, generate MHC-peptide complexes, migrate from the sites of antigen acquisition to secondary lymphoid organs and, finally, they physically interact with and stimulate T lymphocytes.