what are the signs and symptoms of fabry disease?
8209
Symptoms of Fabry disease may include episodes of pain, especially in the hands and feet, clusters of small, dark red spots on the skin called angiokeratomas, a decreased ability to sweat (hypohidrosis), cloudiness of the front part of the eye (corneal opacity), and hearing loss .
1372828
['Fever.', 'Painful, tender joints (arthritis), most commonly in the knees, ankles, elbows, and wrists.', 'Symptoms of congestive heart failure, including chest pain, shortness of breath, fast heartbeat.', 'Fatigue.', 'Jerky, uncontrollable body movements (called “chorea”)']
354961
['increased thirst and a dry mouth.', 'needing to pee frequently.', 'tiredness.', 'blurred vision.', 'unintentional weight loss.', 'recurrent infections, such as thrush, bladder infections (cystitis) and skin infections.', 'tummy pain.', 'feeling or being sick.']
1444230
['Flu-like symptoms such as headaches, dizziness, disorientation, nausea and fatigue.', 'Chest pain in people with coronary heart disease.', 'At higher concentration: impaired vision and coordination, dizziness and confusion.']
209865
['itchiness.', 'headache.', 'dizziness.', 'getting easily bruised or bleeding.', 'sweating more than usual.', 'painful joint swelling.', 'abnormal weight loss.', 'a yellow tint to the eyes and skin (jaundice)']
809157
['gradually worsening vision.', 'sudden vision loss.', 'shapes floating in your field of vision (floaters)', 'blurred or patchy vision.', 'eye pain or redness.']
1401324
['Black, tarry stools.', 'bleeding under the skin.', 'burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings.', 'difficulty in breathing.', 'dizziness or lightheadedness.', 'drowsiness.', 'feeling of constant movement of self or surroundings.', 'general feeling of discomfort, illness, or weakness.']
1451942
['"Brain fog." This is the most common characteristic of gluten sensitivity. Kids with brain fog may often feel tired, or like they just got out of bed. ... ', 'Headaches or migraines. ... ', 'Dizziness.', 'Acne or rashes. ... ', 'Joint pain or numbness. ... ', 'Diarrhea, gas or constipation.', 'Distended stomach or bloating.']
82388
['A lack of muscle control or coordination of voluntary movements (ataxia)', 'Painful, disfiguring skin lesions.', 'Gastrointestinal symptoms, such as heartburn and nausea.', 'Sensitivity to sunlight (photosensitivity)', 'Numbness.', 'Reduced ability to sense pain or extreme temperatures.']
592243
['Rashes, hives, and itching.', 'Shortness of breath.', 'Body swelling.', 'Constipation.', 'Irregular heartbeat.', 'Dizziness.', 'Fainting.', 'Difficulties in breathing and swallowing.']
586276
['loss of appetite.', 'weight loss.', 'weakness.', 'fatigue.', 'nosebleeds.', 'itchy skin.', 'yellow skin and eyes.', 'web-like clusters of blood vessels under your skin.']
430334
['Not peeing or having very dark yellow pee.', 'Very dry skin.', 'Feeling dizzy.', 'Rapid heartbeat.', 'Rapid breathing.', 'Sunken eyes.', 'Sleepiness, lack of energy, confusion or irritability.', 'Fainting.']
760822
['Bleeding easily.', 'Bruising easily.', 'Fatigue.', 'Poor appetite.', 'Yellow discoloration of the skin and eyes (jaundice)', 'Dark-colored urine.', 'Itchy skin.', 'Fluid buildup in your abdomen (ascites)']
656157
Fabry disease also involves potentially life-threatening complications such as progressive kidney damage, heart attack, and stroke. Some affected individuals have milder forms of the disorder that appear later in life and affect only the heart or kidneys.
52072
['Fatigue.', 'Shortness of breath.', 'Dizziness.', 'Pale or yellowish skin.', 'Irregular heartbeats.', 'Weight loss.', 'Numbness or tingling in your hands and feet.', 'Muscle weakness.']
1221063
['Fatigue.', 'Weakness.', 'Pale skin and gums.', 'Shortness of breath.', 'A fast or irregular heartbeat.']
67687
['fatigue (extreme tiredness), which may be a sign of iron deficiency anaemia or vitamin B12 folate deficiency anaemia.', 'unexpected weight loss.', 'an itchy rash (see below)', 'difficulty getting pregnant.', 'tingling and numbness in your hands and feet (peripheral neuropathy)']