are cyclophosphamide and cyclosporine the same thing?
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Brief Summary: Intravenous cyclophosphamide is considered to be the standard of care for treatment of proliferative lupus nephritis. However, its use is limited by potentially severe toxic effects. Cyclosporine A has been suggested to be an efficient and safe treatment alternative to cyclophosphamide.
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Acyclovir is the most frequently prescribed antiviral agent. It has been available for clinical use for over two decades and has demonstrated remarkable safety and efficacy against mild to severe infections caused by HSV and VZV in both normal and immunocompromised patients.
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Prednisone is associated with acne, striae, cushingoid facies, truncal obesity, easy bruising, osteoporosis, and weight gain. However, other immunosuppressants produce their share of physical side effects. Cyclosporine (CsA) causes gingival hyperplasia and hirsutism, and tacrolimus (TAC) can lead to alopecia.
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Myfortic (mycophenolic acid) is good at preventing organ transplant rejection, but you'll need regular blood tests. CellCept (mycophenolate) is a first-choice medication for preventing organ rejection since it doesn't hurt the kidneys or liver like its alternatives.
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Your course of R-CHOP prednisolone as a tablet. rituximab as an infusion. cyclophosphamide as a slow injection (bolus) into a vein. doxorubicin as a slow injection (bolus) into a vein.
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Prograf (tacrolimus) is an immunosuppressant used together with other medicines to prevent your body from rejecting a heart, liver, or kidney transplant. Some forms of Prograf are available in generic form.
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Cytotoxic drugs are hazardous substances, as defined by the Control of Substances Hazardous to Health Regulations 2002 (COSHH). Under COSHH, employers must assess the risks from handling cytotoxic drugs for employees and anyone else affected by this type of work, and take suitable precautions to protect them.
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Immunosuppressant drugs are a class of drugs that suppress, or reduce, the strength of the body's immune system. Some of these drugs are used to make the body less likely to reject a transplanted organ, such as a liver, heart, or kidney.
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Primary systemic treatment. Management of chronic GVHD has relied on corticosteroids as the mainstay of treatment of >3 decades. Systemic treatment typically begins with prednisone at 0.5 to 1 mg/kg per day, followed by a taper to reach an alternate-day regimen, with or without cyclosporine or tacrolimus.
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Cisplatin is classified as an alkylating agent. Alkylating agents are most active in the resting phase of the cell. These drugs are cell cycle non-specific. Note: We strongly encourage you to talk with your health care professional about your specific medical condition and treatments.
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Apotex's first biosimilar, Grastofil (filgrastim), was approved by Health Canada in December 2015 for the treatment of neutropenia in adults and children receiving chemotherapy [1]. Lapelga is also currently under the US Food and Drug Administration review [2].
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Uses. Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis.
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Azathioprine is used to prevent organ rejection in people who have received a kidney transplant. It is usually taken along with other medications to allow your new kidney to function normally. Azathioprine is also used to treat rheumatoid arthritis.
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Disease-modifying anti-rheumatic drugs DMARDs, such as azathioprine, methotrexate, cyclophosphamide or mycophenolate, suppress your immune system and help reduce swelling. These medicines take time to work, but in the long term, they may help you to reduce your dose of steroids.
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Individuals taking oral blood thinners or anticoagulants, for example, warfarin, (Coumadin), should avoid oxaprozin because oxaprozin also thins the blood, and excessive blood thinning may lead to bleeding. Oxaprozin increases the negative effect of cyclosporine on kidney function.
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Romiplostim is used for the treatment of thrombocytopenia (low platelets) in patients with chronic immune (idiopathic) thrombocytopenia purpura (ITP) who have had insufficient response to corticosteroids, immune globulin, or splenectomy. Nplate is not indicated to normalize platelet counts.
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The most significant side effect of immunosuppressant drugs is an increased risk of infection. Other, less serious side effects can include loss of appetite, nausea, vomiting, increased hair growth, and hand trembling. These effects typically subside as the body adjusts to the immunosuppressant drugs.