is sjogrens a connective tissue disease?
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About 25% of patients with a connective tissue disease (such as dermatomyositis, rheumatoid arthritis, Sjogren's syndrome, and the 3 disease listed above), develop another connective tissue disease over the course of several years. This is known as an "overlap syndrome."
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If autoimmune diseases, including rheumatoid arthritis, Sjögrens syndrome and scleroderma, affect your lungs, they can cause pulmonary fibrosis. Unfortunately some of the drugs used to treat these diseases can also cause interstitial lung disease as a side effect.
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Early indications of mixed connective tissue disease can include: General feeling of being unwell. This can include increased fatigue and a mild fever. Cold and numb fingers or toes (Raynaud's phenomenon).
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Sjogren's syndrome, another autoimmune disease, can attack many parts of the body, but it often affects the salivary glands and the tear ducts. This results in dry eyes and dry mouth, and dry mouth can lead to oral thrush.
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Joint pain is one of the most common symptoms of Sjögren's syndrome. Multiple joints are painful, usually episodically with periods of joint pain, known as “flares”, followed by periods of little or no joint pain. Tenderness and swelling of the joints, when present, are indicative of inflammatory arthritis.
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Summary. Mixed connective tissue disease (MCTD) is a rare autoimmune disorder that is characterized by features commonly seen in three different connective tissue disorders: systemic lupus erythematosus, scleroderma, and polymyositis. Some affected people may also have symptoms of rheumatoid arthritis.
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Antibodies to ribonucleoprotein, RNP, are found often in very high levels in patients with a variety of systemic rheumatic diseases, including SLE, progressive systemic sclerosis and Mixed Connective Tissue Disease, a distinct disease entity with overlapping clinical features of SLE, scleroderma, polymyositis and ...
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In the beginning stages, patients who have MCTD have symptoms similar to those of patients with other connective tissue disorders, including: Fatigue. Muscle pain with no apparent cause. Joint pain.
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Systemic lupus erythematosus (lupus) is a chronic, inflammatory autoimmune disorder affecting the connective tissue. In autoimmune disorders, the body's own immune system attacks healthy cells and tissues causing inflammation and malfunction of various organ systems.
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Digestive tract damage. Commonly, mixed connective tissue disease affects the digestive tract. You might have abdominal pain and problems with swallowing and digesting food.
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Fibromyalgia and Sjögren's Syndrome. Studies have explored the possibility of fibromyalgia and Sjögren's syndrome coexisting in a patient. Researchers have found that fibromyalgia is more common in patients with primary Sjögren's syndrome who complain of fatigue as their main symptom.
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Autoimmune diseases, like Sjögren's, can impact the body in many different ways. Dry, brittle and thinning hair is a common side effect but not everyone realizes it can be caused by the disease. Identifying and treating problems like hair loss in people with Sjögren's is an important part of managing the disease.
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Lupus and rheumatoid arthritis (RA) are both autoimmune diseases. In fact, the two diseases are sometimes confused because they share many symptoms. Autoimmune disease occurs when your immune system attacks cells in your body, triggering inflammation and damaging healthy tissue.
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['High blood pressure in the lungs (pulmonary hypertension). This condition is a major cause of death in people with mixed connective tissue disease.', 'Interstitial lung disease. ... ', 'Heart disease. ... ', 'Kidney damage. ... ', 'Digestive tract damage. ... ', 'Anemia. ... ', 'Tissue death. ... ', 'Hearing loss.']
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Related Disorders Systemic lupus erythematosus (lupus) is a chronic, inflammatory autoimmune disorder affecting the connective tissue. In autoimmune disorders, the body's own immune system attacks healthy cells and tissues causing inflammation and malfunction of various organ systems.
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Undifferentiated connective tissue disease (UCTD) is a systemic autoimmune disease. This means the body's natural immune system does not behave normally. Instead of serving to fight infections such as bacteria and viruses, the body's own immune system attacks itself.
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In addition, Sjogren's syndrome may cause skin, nose, and vaginal dryness, and may affect other organs of the body including the kidneys, blood vessels, lungs, liver, pancreas, and brain. Sjögren's syndrome affects 1-4 million people in the United States. Most people are more than 40 years old at the time of diagnosis.