Task: Please answer the multiple choice question.
Question: Which molecules are a human ether-à-go-go related gene (hERG) blocker (<10uM)?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1ccc2ncc(Cl)c(CCN3CCC(NCc4cc5c(cn4)OCCO5)CC3)c2n1
b O=S(=O)(c1ccccc1)c1ccc(/C=C/c2ccc(F)cc2F)cc1
c CC(=O)C1=NN2c3cc(Cl)ccc3OC[C@H]2[C@@]1(CCCN(C)C)c1ccccc1
d CCCC(=O)NC1CCc2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc21
e CN1CCC(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(Cl)c3Cl)c2O)CC1
Answer: a, b, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {herg_blocker#not &NULL}a {herg_blocker__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_blocker%}
Answer: {%multiple_choice_result}
1-[2-(3-chloro-6-methoxy-1,5-naphthyridin-4-yl)ethyl]-N-(2,3-dihydro-[1,4]dioxino[2,3-c]pyridin-7-ylmethyl)piperidin-4-amine