Task: Please answer the multiple choice question.
Question: Which molecules are a human ether-à-go-go related gene (hERG) blocker (<10uM)?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Cn1c(SCCCN2CC[C@]3(C[C@@H]3c3ccc(C(F)(F)F)cc3)C2)nnc1-c1ccncc1
b O=C(O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(Cl)cc2F)n1
c CC(=O)Nc1cccc(Nc2ncnc(N3CCC(OCc4ccc(C(F)(F)F)cc4)CC3)n2)c1C
d Cn1ncc(C(=O)N2CCC(Nc3cc(=O)n(C)c4ccccc34)CC2)c1Cl
e Cc1nc2ccccc2n1-c1ccc(C(=O)N(C)[C@@H]2CCN(C(C)C)C2)cc1
Answer: a
Task: Please answer the multiple choice question.
Question: Which molecules are {herg_blocker#not &NULL}a {herg_blocker__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_blocker%}
Answer: {%multiple_choice_result}
(2R,3S)-5-[3-[(4-methyl-5-pyridin-4-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2-[4-(trifluoromethyl)phenyl]-5-azaspiro[2.4]heptane