Task: Please answer the multiple choice question.
Question: Which molecules are a human ether-à-go-go related gene (hERG) blocker (<10uM)?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. COc1ccc(Cn2cnc3c(NS(C)(=O)=O)c(C)c(C)cc32)cc1
b. O=c1ccc2ncc(F)c3c2n1C[C@@]3(O)CC12CCC(NCc3cc4c(cn3)SCCO4)(CC1)CO2
c. COc1cc(N2C(=O)N(c3ccc(-c4ccc5[nH]ncc5c4)cc3)C(=O)C23CCN(Cc2ncccc2C)CC3)ncn1
d. Fc1cccnc1-c1ccc2[nH]nc(-c3cncc(O[C@H]4CNCCC45CC5)n3)c2c1
Answer: c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {herg_blocker#not &NULL}a {herg_blocker__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_blocker%}
Answer: {%multiple_choice_result}
3-[4-(1H-indazol-5-yl)phenyl]-1-(6-methoxypyrimidin-4-yl)-8-[(3-methylpyridin-2-yl)methyl]-1,3,8-triazaspiro[4.5]decane-2,4-dione