Problem statement: Answer the multiple-choice question.
Question: Which drug has a 3.550\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COC(=O)c1ccc(CNC(=O)c2cc3ccccc3oc2=O)cc1
(b) CN(CC(=O)Nc1ccc(Cl)cc1)C(=O)COc1ncnc2ccccc12
(c) CCN(CC)C(=O)CSc1nnc(-c2ccc(S(=O)(=O)N3CCOCC3)cc2)n1C
(d) COc1ccc(NC(=O)CSCC(=O)Oc2c(OC)cccc2OC)cc1
(e) CN(CC(=O)Nc1ccc(Cl)cc1)C(=O)c1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2)cc1
Answer: b. CN(CC(=O)Nc1ccc(Cl)cc1)C(=O)COc1ncnc2ccccc12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(CC(=O)Nc1ccc(Cl)cc1)C(=O)COc1ncnc2ccccc12
CN(CC(=O)Nc1ccc(Cl)cc1)C(=O)COc1ncnc2ccccc12
N-(4-chlorophenyl)-2-[methyl-(2-quinazolin-4-yloxyacetyl)amino]acetamide