Problem statement: Answer the MCQ question.
Query: Which compound has a -10.300\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
[a] COc1cc(C(c2nnnn2C(C)(C)C)N2CCN(c3nc4ccccc4s3)CC2)ccc1O
[b] O=C(c1ccc(Cl)cc1)N1CCOc2ccccc21
[c] COc1ccc(C)cc1NS(=O)(=O)c1ccc(-c2cnc(C3CC3)o2)cc1
[d] O=S(=O)(Cc1ccccc1)NCC1CCCN(Cc2cccc3nonc23)C1
Answer: d. O=S(=O)(Cc1ccccc1)NCC1CCCN(Cc2cccc3nonc23)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=S(=O)(Cc1ccccc1)NCC1CCCN(Cc2cccc3nonc23)C1
O=S(=O)(Cc1ccccc1)NCC1CCCN(Cc2cccc3nonc23)C1
N-[[1-(2,1,3-benzoxadiazol-4-ylmethyl)piperidin-3-yl]methyl]-1-phenylmethanesulfonamide