Problem statement: Answer the multiple-choice question.
Question: Which compound has a 11.884\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccc(-n2c3c(cc(C(=O)Nc4cccc(C)n4)c2=O)C(=O)CC(C)(C)C3)cc1
[b] CCN1CCN(C(=O)COc2ccc(S(=O)(=O)NC(C)C)cc2)CC1
[c] Cc1c(Cl)cccc1NC(=O)COC(=O)Cc1ccsc1
[d] O=S(=O)(c1ccc(F)cc1)N(CCO)CC(O)Cn1c2ccccc2c2ccccc21
[e] COC(=O)c1ccc(/C=C2/SC(=S)N(CCC(=O)NCCCN3CCOCC3)C2=O)cc1
Answer: b. CCN1CCN(C(=O)COc2ccc(S(=O)(=O)NC(C)C)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN1CCN(C(=O)COc2ccc(S(=O)(=O)NC(C)C)cc2)CC1
CCN1CCN(C(=O)COc2ccc(S(=O)(=O)NC(C)C)cc2)CC1
4-[2-(4-ethylpiperazin-1-yl)-2-oxoethoxy]-N-propan-2-ylbenzenesulfonamide