Problem statement: Answer the multiple choice question.
Query: Which drug has a -1.838\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(N2C(=O)c3ccccc3NC2c2ccc(OC)c(CSc3ccccn3)c2)cc1
b. CCCC(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccco2)s1
c. COc1ccc(C(=O)Cn2cnc3ccc(Cl)cc3c2=O)cc1F
d. CCCCCc1ccc(-c2cn(CN3C(=O)c4ccccc4C3=O)nn2)cc1
e. Cc1ccc(CNC(=O)C(=O)NCCC2CCCCN2S(=O)(=O)c2cccs2)cc1
Answer: d. CCCCCc1ccc(-c2cn(CN3C(=O)c4ccccc4C3=O)nn2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCCc1ccc(-c2cn(CN3C(=O)c4ccccc4C3=O)nn2)cc1
CCCCCc1ccc(-c2cn(CN3C(=O)c4ccccc4C3=O)nn2)cc1
2-[[4-(4-pentylphenyl)triazol-1-yl]methyl]isoindole-1,3-dione