Task: Answer the multiple-choice question.
Question: Which drug exhibits a 21.508\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CCC(=O)NNC(=O)c1cc(COc2cc(Cl)cc(Cl)c2)on1
[b] CC#CCN1c2ccccc2[C@]23C[C@@H](C(=O)OC)N(C(=O)NC(C)(C)C)C2=NC(C(=O)OC)=C(C(=O)OC)[C@H]13
[c] COc1cccc(C2CC(c3c(F)cccc3Cl)n3nc(N)nc3N2)c1
[d] Cc1ccc(/C=N/NC(=O)CN(Cc2ccccc2)S(=O)(=O)c2ccc3c(c2)OCCO3)cc1
[e] COC(=O)Nc1ccc(S(=O)(=O)N2CCCC(C(=O)N3CCC(C)CC3)C2)cc1
Answer: b. CC#CCN1c2ccccc2[C@]23C[C@@H](C(=O)OC)N(C(=O)NC(C)(C)C)C2=NC(C(=O)OC)=C(C(=O)OC)[C@H]13
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC#CCN1c2ccccc2[C@]23C[C@@H](C(=O)OC)N(C(=O)NC(C)(C)C)C2=NC(C(=O)OC)=C(C(=O)OC)[C@H]13
CC#CCN1c2ccccc2[C@]23C[C@@H](C(=O)OC)N(C(=O)NC(C)(C)C)C2=NC(C(=O)OC)=C(C(=O)OC)[C@H]13
trimethyl (1S,9R,15S)-14-(tert-butylcarbamoyl)-8-but-2-ynyl-8,12,14-triazatetracyclo[7.7.0.01,13.02,7]hexadeca-2,4,6,10,12-pentaene-10,11,15-tricarboxylate