Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -1.979\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccc(C(=O)N[C@H](C(=O)OCc2nc3ccsc3c(=O)[nH]2)C(C)C)cc1
[b] Cc1cc(-c2nn(-c3ccccc3F)cc2CN2CCCC(CO)C2)c(C)s1
[c] O=C(CN1C(=O)NC2(CCc3ccccc32)C1=O)c1c[nH]c2ccccc12
[d] Cl.c1ccc(CC2=NCCN2)cc1
[e] CCOc1ccc(N(C)C(=O)CCc2nnc3ccc(N4CCOCC4)nn23)cc1
Answer: a. COc1ccc(C(=O)N[C@H](C(=O)OCc2nc3ccsc3c(=O)[nH]2)C(C)C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)N[C@H](C(=O)OCc2nc3ccsc3c(=O)[nH]2)C(C)C)cc1
COc1ccc(C(=O)N[C@H](C(=O)OCc2nc3ccsc3c(=O)[nH]2)C(C)C)cc1
(4-oxo-3H-thieno[3,2-d]pyrimidin-2-yl)methyl (2S)-2-[(4-methoxybenzoyl)amino]-3-methylbutanoate