Problem statement: Answer the multiple-choice question.
Question: Which drug has a 21.119\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C(c1cnc2n(c1=O)CCS2)N(c1ccccc1)C1CCCCC1
b) NC(=O)CC(NC(=O)c1ccccc1)c1ccc(NCCCN2CCCC2=O)c([N+](=O)[O-])c1
c) COc1cc(CC(NC(C)=O)C(=O)NC2CCN(S(=O)(=O)c3ccc(NC(C)=O)cc3)CC2)cc(OC)c1
d) CCN(CC)CCOC(=O)c1c(C)n(C)c2ccc(OC)cc12.Cl
e) Cc1c(NC(=O)c2ccc3c(c2)C(=O)N(Cc2ccco2)C3=O)cccc1C(=O)O
Answer: c. COc1cc(CC(NC(C)=O)C(=O)NC2CCN(S(=O)(=O)c3ccc(NC(C)=O)cc3)CC2)cc(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(CC(NC(C)=O)C(=O)NC2CCN(S(=O)(=O)c3ccc(NC(C)=O)cc3)CC2)cc(OC)c1
COc1cc(CC(NC(C)=O)C(=O)NC2CCN(S(=O)(=O)c3ccc(NC(C)=O)cc3)CC2)cc(OC)c1
2-(acetylamino)-N-[1-(4-acetamidophenyl)sulfonylpiperidin-4-yl]-3-(3,5-dimethoxyphenyl)propanamide