Task: Answer the multiple choice question.
Question: Which drug has a -2.739\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C(CCN1C(=O)/C(=C/c2ccccc2)SC1=S)NNC(=O)c1cccnc1
b. CC(C)OC(=O)CC1C(=O)NCCN1C(=S)NC(=O)c1ccccc1Cl
c. CCOC(=O)Cc1csc(NC(=O)c2ccc(C)c(S(=O)(=O)N3CCOCC3)c2)n1
d. CCN(CC)C(=O)N1CCN(Cc2ccc3c(c2)OCO3)CC1
e. Cc1ccc(S(=O)(=O)Nc2ccccc2CNc2ncc(Br)cc2Br)cc1
Answer: c. CCOC(=O)Cc1csc(NC(=O)c2ccc(C)c(S(=O)(=O)N3CCOCC3)c2)n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)Cc1csc(NC(=O)c2ccc(C)c(S(=O)(=O)N3CCOCC3)c2)n1
CCOC(=O)Cc1csc(NC(=O)c2ccc(C)c(S(=O)(=O)N3CCOCC3)c2)n1
ethyl 2-[2-[(4-methyl-3-morpholin-4-ylsulfonylbenzoyl)amino]-1,3-thiazol-4-yl]acetate