Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 10.495\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CCN(CC)CCNc1ccc(Cl)cc1[N+](=O)[O-].Cl
b.) CCC1C(=O)N(c2nc(C)cc(C)n2)N=C1C
c.) O=C(CCC(=O)N1CCOCC1)Nc1nnc(C2CCCCC2)s1
d.) CCCCNC(=O)[C@H]1C[C@H]1[C@@H](O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C
e.) Cc1ccc(S(=O)(=O)N2CCC(C(=O)N[C@H](C(=O)NCC3CCCO3)C(C)C)CC2)cc1
Answer: d. CCCCNC(=O)[C@H]1C[C@H]1[C@@H](O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCNC(=O)[C@H]1C[C@H]1[C@@H](O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C
CCCCNC(=O)[C@H]1C[C@H]1[C@@H](O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C
tert-butyl N-[(2S)-1-[[(1R,2S)-1-[(1R,2S)-2-(butylcarbamoyl)cyclopropyl]-1,3-dihydroxypropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]carbamate