Problem statement: Answer the multiple-choice question.
Question: Which compound has a -2.021\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
[a] COc1ccc(NC(=S)NCC2CCN(c3ccc(OC)cc3)C2)cc1
[b] COCc1[nH][nH]c(=O)c1C=Nc1ccc(C(F)(F)F)cc1
[c] COc1cc(/C=C/c2nc3ccc([N+](=O)[O-])cc3s2)ccc1OCC(=O)O
[d] CC(C)Nc1nc(NC(C)C)nc(OCCOC(=O)c2ccccc2)n1
Answer: b. COCc1[nH][nH]c(=O)c1C=Nc1ccc(C(F)(F)F)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCc1[nH][nH]c(=O)c1C=Nc1ccc(C(F)(F)F)cc1
COCc1[nH][nH]c(=O)c1C=Nc1ccc(C(F)(F)F)cc1
5-(methoxymethyl)-4-[[4-(trifluoromethyl)phenyl]iminomethyl]-1,2-dihydropyrazol-3-one