Problem statement: Answer the MCQ question.
Question: Which drug has a -0.428\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: O=c1[nH]c(SCc2cccc([N+](=O)[O-])c2)nc2[nH]ncc12
b: CC1CN(C(=O)CCC(=O)N2CCCCC2)c2ccccc2O1
c: OCCC1CN(Cc2cnc(N3CCCC3)s2)CCN1Cc1ccccc1
d: COCCN(C(=O)COC(=O)Cc1cccc2ccccc12)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O
e: COc1ccc(C(CNC(=O)c2cc(S(=O)(=O)N3CCCC3)ccc2Cl)N2CCCC2)cc1
Answer: d. COCCN(C(=O)COC(=O)Cc1cccc2ccccc12)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCN(C(=O)COC(=O)Cc1cccc2ccccc12)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O
COCCN(C(=O)COC(=O)Cc1cccc2ccccc12)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O
[2-[(6-amino-1-benzyl-2,4-dioxopyrimidin-5-yl)-(2-methoxyethyl)amino]-2-oxoethyl] 2-naphthalen-1-ylacetate