Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -2.818\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: Cc1c(-c2ccccc2)nc2ccccc2c1C(=O)O
b: CC(=O)Oc1c(C)c2c3c(c1OC(C)=O)[C@@H](C)CC[C@@H]3[C@@H](C)C[C@H]2C=C(C)C
c: O=S(=O)(Nc1ccc(-c2ccc3nncn3n2)cc1)c1ccc(Cl)s1
d: CNc1nc(OC)nc(N2CCOCC2)n1
e: Cc1c(CC(C)C)nc(N)c(C#N)c1-c1ccccc1
Answer: c. O=S(=O)(Nc1ccc(-c2ccc3nncn3n2)cc1)c1ccc(Cl)s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=S(=O)(Nc1ccc(-c2ccc3nncn3n2)cc1)c1ccc(Cl)s1
O=S(=O)(Nc1ccc(-c2ccc3nncn3n2)cc1)c1ccc(Cl)s1
5-chloro-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]thiophene-2-sulfonamide