Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 1.411\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccccc1NC(NC(=O)c1ccccn1)C(Cl)(Cl)Cl
b. COc1cc(NC(=O)c2cc3c(CO)cnc(C)c3oc2=Nc2cccc(C(N)=O)c2)cc(OC)c1
c. COCc1cc(C)nc(OCC(=O)N/N=C/c2ccc(C)o2)c1C#N
d. Cc1cc(NC(=O)Cn2c(=O)c3c(ncn3CC(C)C)n(Cc3ccccc3)c2=O)no1
e. COc1ccc(-c2cc(C(=O)NC(C)c3ccccn3)c3ccccc3n2)cc1OC
Answer: a. COc1ccccc1NC(NC(=O)c1ccccn1)C(Cl)(Cl)Cl
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1NC(NC(=O)c1ccccn1)C(Cl)(Cl)Cl
COc1ccccc1NC(NC(=O)c1ccccn1)C(Cl)(Cl)Cl
N-[2,2,2-trichloro-1-(2-methoxyanilino)ethyl]pyridine-2-carboxamide