Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -5.013\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: Cc1cc(NC(=O)COC(=O)CSc2nc3cc(Cl)ccc3n2Cc2ccccc2)no1
b: COc1cc(CN2CCC(C(=O)N3CCCC(C)C3)CC2)cc(Br)c1O.O=C(O)C(=O)O
c: CCOc1ccc2[nH]c(=O)c(CN(Cc3ccc(C)cc3)C(=O)N3CCCC3)cc2c1
d: CCOC(=O)C1=C(C)N(c2ccccc2)C(=O)NC1c1cccc([N+](=O)[O-])c1
Answer: d. CCOC(=O)C1=C(C)N(c2ccccc2)C(=O)NC1c1cccc([N+](=O)[O-])c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1=C(C)N(c2ccccc2)C(=O)NC1c1cccc([N+](=O)[O-])c1
CCOC(=O)C1=C(C)N(c2ccccc2)C(=O)NC1c1cccc([N+](=O)[O-])c1
ethyl 4-methyl-6-(3-nitrophenyl)-2-oxo-3-phenyl-1,6-dihydropyrimidine-5-carboxylate