Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 19.596\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) Cc1ccccc1-n1nc2c(c1NC(=O)c1cccs1)CS(=O)(=O)C2
(b) COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccccc1Cl
(c) CC(C)(C)OC(=O)CC[C@H](NC(=O)C1CCN(C(=O)OC(C)(C)C)CC1)c1nnc([C@H](Cc2ccc(OC(C)(C)C)cc2)NC(=O)OC(C)(C)C)o1
(d) Cc1cc(NS(=O)(=O)c2ccc(NC(=O)COc3cc(C)c(Cl)c(C)c3)cc2)no1
(e) COc1ccc(C(=O)NCC(=O)N2CCN(c3ncccn3)CC2)cc1OC
Answer: e. COc1ccc(C(=O)NCC(=O)N2CCN(c3ncccn3)CC2)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)NCC(=O)N2CCN(c3ncccn3)CC2)cc1OC
COc1ccc(C(=O)NCC(=O)N2CCN(c3ncccn3)CC2)cc1OC
3,4-dimethoxy-N-[2-oxo-2-(4-pyrimidin-2-ylpiperazin-1-yl)ethyl]benzamide