Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 11.885\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C1N[C@@H](Cc2cn(S(=O)(=O)c3ccc([N+](=O)[O-])cc3)c3ccccc23)C(=O)N[C@H]1Cc1ccccc1
b) NC(=NCCc1ccc(Cl)cc1)NS(=O)(=O)c1ccccc1
c) O=C(NCCOc1cccc(Oc2ccccc2)c1)c1cc(-n2cnnc2)ccc1Cl
d) Cc1ccccc1C1C2=C(Nc3[nH]n(-c4ccccc4)c(=O)c31)c1ccccc1C2=O
e) CCCNC(=O)N1[C@H]2CC[C@@H]1C(C(=O)OC)=C(c1ccc(F)cc1OCc1ccccc1)C2
Answer: e. CCCNC(=O)N1[C@H]2CC[C@@H]1C(C(=O)OC)=C(c1ccc(F)cc1OCc1ccccc1)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCNC(=O)N1[C@H]2CC[C@@H]1C(C(=O)OC)=C(c1ccc(F)cc1OCc1ccccc1)C2
CCCNC(=O)N1[C@H]2CC[C@@H]1C(C(=O)OC)=C(c1ccc(F)cc1OCc1ccccc1)C2
methyl (1R,5S)-3-(4-fluoro-2-phenylmethoxyphenyl)-8-(propylcarbamoyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate