Problem statement: Answer the MCQ question.
Question: Which compound exhibits a -0.811\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) C=CC[n+]1c(-c2ccc(Cl)cc2Cl)csc1Nc1ccc(NC(C)=O)cc1.[Cl-]
(b) Cc1ccc(NS(=O)(=O)c2ccc(OCC(=O)NCc3cccnc3)cc2)cc1
(c) COc1ccc(C(CNC(=O)Nc2ccccc2)N2CCN(C)CC2)cc1
(d) CCSc1ccccc1-c1nc(-c2ccncc2)no1
(e) COc1ccccc1N1CCN(Cc2ccc(Br)cc2)CC1.O=C(O)C(=O)O
Answer: c. COc1ccc(C(CNC(=O)Nc2ccccc2)N2CCN(C)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(CNC(=O)Nc2ccccc2)N2CCN(C)CC2)cc1
COc1ccc(C(CNC(=O)Nc2ccccc2)N2CCN(C)CC2)cc1
1-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]-3-phenylurea