Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 10.281\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) COc1cc2c(cc1OC)C(C)N(C(=O)C1=NN(c3cccc(C)c3)C(=O)CC1)CC2
b) Cc1ccc(Nc2cc(C)nc3ncnn23)c(C)c1
c) O=C(NNC(=O)c1ccc2c(c1)OCO2)NC12CC3CC(CC(C3)C1)C2
d) Cc1ccc(C(=O)OCC(=O)c2c[nH]c3ccccc23)cc1NC(=O)c1ccco1
Answer: a. COc1cc2c(cc1OC)C(C)N(C(=O)C1=NN(c3cccc(C)c3)C(=O)CC1)CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(C)N(C(=O)C1=NN(c3cccc(C)c3)C(=O)CC1)CC2
COc1cc2c(cc1OC)C(C)N(C(=O)C1=NN(c3cccc(C)c3)C(=O)CC1)CC2
6-(6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinoline-2-carbonyl)-2-(3-methylphenyl)-4,5-dihydropyridazin-3-one