Problem statement: Answer the multiple choice question.
Question: Which compound exhibits a 11.117\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1ccc(C(=O)[C@H]2[C@H]3C(=O)N(c4ccc(OC(C)=O)cc4)C(=O)[C@H]3C3C=CC=NN32)cc1
b: CC(=O)Nc1nc(CC(C)C)cc(-c2ccco2)c1C#N
c: C=CCSc1nnc(-c2ccccc2NC(=O)CC)c(=O)[nH]1
d: Cc1c(C(=O)NC2CCCCC2C)oc2ccccc12
e: Cc1ccc(-c2nc(SCC(N)=O)c(C#N)c3c2CCCC3)cc1
Answer: a. COc1ccc(C(=O)[C@H]2[C@H]3C(=O)N(c4ccc(OC(C)=O)cc4)C(=O)[C@H]3C3C=CC=NN32)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)[C@H]2[C@H]3C(=O)N(c4ccc(OC(C)=O)cc4)C(=O)[C@H]3C3C=CC=NN32)cc1
COc1ccc(C(=O)[C@H]2[C@H]3C(=O)N(c4ccc(OC(C)=O)cc4)C(=O)[C@H]3C3C=CC=NN32)cc1
[4-[(2R,6S,7R)-7-(4-methoxybenzoyl)-3,5-dioxo-4,8,9-triazatricyclo[6.4.0.02,6]dodeca-9,11-dien-4-yl]phenyl] acetate