Problem statement: Answer the MCQ question.
Query: Which drug has a -0.838\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1cccc(CNC(=O)c2ccc3nc(Cc4ccccc4F)oc3c2)n1
b) CSc1nnc(-c2ccc(C(F)(F)F)nc2C)o1
c) CCc1noc(C)c1C(=O)N1CCN(S(=O)(=O)c2ccc(C(C)=O)cc2)CC1
d) COc1ccc(S(=O)(=O)N2CCOC2CNC(=O)C(=O)NCc2ccncc2)cc1C
e) O=C(Oc1ccc(C(=S)N2CCC(O)CC2)cc1)c1ccc(Cl)cc1
Answer: c. CCc1noc(C)c1C(=O)N1CCN(S(=O)(=O)c2ccc(C(C)=O)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCc1noc(C)c1C(=O)N1CCN(S(=O)(=O)c2ccc(C(C)=O)cc2)CC1
CCc1noc(C)c1C(=O)N1CCN(S(=O)(=O)c2ccc(C(C)=O)cc2)CC1
1-[4-[4-(3-ethyl-5-methyl-1,2-oxazole-4-carbonyl)piperazin-1-yl]sulfonylphenyl]ethanone