Task: Answer the multiple-choice question.
Question: Which compound has a 12.857\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COc1ccc(NC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)cc1
b.) Cc1[nH]c(C)c(S(=O)(=O)N2CCN(c3cccc(Cl)c3)CC2)c1C(=O)N1CCCCC1
c.) CC1(C)CC(=O)C2=C(C1)OC(N)=C(C#N)C2c1ccoc1
d.) CCOC(=O)[C@@H]1[C@H]2COc3ccccc3[C@@H]2N2C(=O)N(c3ccc(Cl)cc3)C(=O)[C@]12C
e.) COc1ccc2oc(C(=O)OCC(=O)N3CC(C)OC(C)C3)c(C)c2c1
Answer: d. CCOC(=O)[C@@H]1[C@H]2COc3ccccc3[C@@H]2N2C(=O)N(c3ccc(Cl)cc3)C(=O)[C@]12C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)[C@@H]1[C@H]2COc3ccccc3[C@@H]2N2C(=O)N(c3ccc(Cl)cc3)C(=O)[C@]12C
CCOC(=O)[C@@H]1[C@H]2COc3ccccc3[C@@H]2N2C(=O)N(c3ccc(Cl)cc3)C(=O)[C@]12C
ethyl(1R,10R,11R,12S)-14-(4-chlorophenyl)-12-methyl-13,15-dioxo-8-oxa-14,16-diazatetracyclo[8.6.0.02,7.012,16]hexadeca-2,4,6-triene-11-carboxylate