Problem statement: Answer the multiple-choice question.
Question: Which compound has a 13.828\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Cc1cc(N=Cc2c(O)n(-c3ccc4c(c3)OCO4)c(=O)c3ccccc23)ccn1
b COC(=O)Cn1cc(C(=O)C(C)(C)C)c2ccccc21
c CCn1c(=O)c(C(=O)Nc2ncccc2O)c(O)c2ccccc21
d COc1ccc(NC(=O)c2sc3nc(C)nc(N4CCN(c5ccccn5)CC4)c3c2C)c(OC)c1
e COc1cc(OC)cc(C(=O)N[C@H](C(=O)NCCc2c[nH]c3ccccc23)C(C)C)c1
Answer: d. COc1ccc(NC(=O)c2sc3nc(C)nc(N4CCN(c5ccccn5)CC4)c3c2C)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)c2sc3nc(C)nc(N4CCN(c5ccccn5)CC4)c3c2C)c(OC)c1
COc1ccc(NC(=O)c2sc3nc(C)nc(N4CCN(c5ccccn5)CC4)c3c2C)c(OC)c1
N-(2,4-dimethoxyphenyl)-2,5-dimethyl-4-(4-pyridin-2-ylpiperazin-1-yl)thieno[2,3-d]pyrimidine-6-carboxamide