Task: Answer the multiple-choice question.
Question: Which compound has a -3.677\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCOc1cc(C(=O)Nc2ccc(N3CCOCC3)cc2)cc(Br)c1OC
(b) CCc1ccc(NC(=O)CSc2nncn2-c2cccnc2)cc1
(c) COc1ccccc1NC(=O)CN1CCN(CC(=O)Nc2cc(NC(C)=O)ccc2OC)CC1
(d) CCOC(=O)c1ccc(NC(=O)CCNS(=O)(=O)c2cccs2)cc1
(e) O=C(N=C1SC2CS(=O)(=O)CC2N1c1ccccc1F)C1CCCCC1
Answer: c. COc1ccccc1NC(=O)CN1CCN(CC(=O)Nc2cc(NC(C)=O)ccc2OC)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1NC(=O)CN1CCN(CC(=O)Nc2cc(NC(C)=O)ccc2OC)CC1
COc1ccccc1NC(=O)CN1CCN(CC(=O)Nc2cc(NC(C)=O)ccc2OC)CC1
2-[4-[2-(5-acetamido-2-methoxyanilino)-2-oxoethyl]piperazin-1-yl]-N-(2-methoxyphenyl)acetamide