Task: Answer the multiple-choice question.
Query: Which drug exhibits a -13.366\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(-c2csc3ncnc(N4CCN(S(=O)(=O)c5ccccc5C#N)CC4)c23)cc1
(b) CCOc1cc(/C=N\NC(=O)Cc2ccccc2)ccc1OCC(=O)Nc1ccc(C)c(C)c1
(c) COc1ccc(S(=O)(=O)c2nnn(-c3ccccc3Cl)c2N)cc1
(d) COC(=O)C(C(=O)OC)C(C(=O)OC)C(C(=O)OC)C(=O)OC
(e) Cc1nn(C)cc1C(C(=O)NC1CCCCC1)N(CCc1ccccc1)C(=O)c1cnccn1
Answer: e. Cc1nn(C)cc1C(C(=O)NC1CCCCC1)N(CCc1ccccc1)C(=O)c1cnccn1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1nn(C)cc1C(C(=O)NC1CCCCC1)N(CCc1ccccc1)C(=O)c1cnccn1
Cc1nn(C)cc1C(C(=O)NC1CCCCC1)N(CCc1ccccc1)C(=O)c1cnccn1
N-[2-(cyclohexylamino)-1-(1,3-dimethylpyrazol-4-yl)-2-oxoethyl]-N-(2-phenylethyl)pyrazine-2-carboxamide