Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -3.711\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C1C=CC(=O)N1c1ccc(I)cc1Cl
b.) CCc1ccc(-c2cc3c(=O)n(CC(=O)NCCCN4CCC(Cc5ccccc5)CC4)nc(C)n3n2)cc1
c.) CCOC(=O)C1CCN(C(=O)CNC(=O)Cn2c(C)cc3ccccc3c2=O)CC1
d.) COc1nc(Cl)cn(-c2ccc(C)cc2)c1=O
e.) O=c1nc(/C=C/c2ccccc2C(F)(F)F)cc(C(F)(F)F)[nH]1
Answer: d. COc1nc(Cl)cn(-c2ccc(C)cc2)c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1nc(Cl)cn(-c2ccc(C)cc2)c1=O
COc1nc(Cl)cn(-c2ccc(C)cc2)c1=O
5-chloro-3-methoxy-1-(4-methylphenyl)pyrazin-2-one