Task: Answer the multiple-choice question.
Query: Which compound has a 4.864\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCn1c(=O)c2c3c(sc2n2cnnc12)CCC3
(b) CC(C(=O)Nc1ccc(F)c(F)c1F)N1CCCCCC1
(c) COC(=O)C(Cc1ccccc1)NS(=O)(=O)c1ccccc1Br
(d) COc1ccc(NC(=O)C2CCCN(c3cc(C)nc4ncnn34)C2)cc1
(e) CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)CC[C@]5(C)[C@@]4(F)[C@@H](O)C[C@]3(C)[C@]2(C(=O)CCl)O1
Answer: d. COc1ccc(NC(=O)C2CCCN(c3cc(C)nc4ncnn34)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)C2CCCN(c3cc(C)nc4ncnn34)C2)cc1
COc1ccc(NC(=O)C2CCCN(c3cc(C)nc4ncnn34)C2)cc1
N-(4-methoxyphenyl)-1-(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidine-3-carboxamide