Problem statement: Answer the multiple choice question.
Question: Which drug has a 11.978\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=P(OCC(F)(F)C(F)F)(N1CCOCC1)N1CCOCC1
(b) O=C(NC1CCCC1)C(c1ccncc1)N(Cc1ccccc1)C(=O)Cc1cccs1
(c) COc1ccc(/C=C/C(=O)Nc2cc(C(F)(F)F)ccc2Cl)cc1
(d) N#C/C(=C/c1cn(-c2ccccc2)nc1-c1cccc(S(=O)(=O)N2CCCC2)c1)C(=O)NCc1ccco1
(e) Cc1ccc(-n2c(-c3ccc(Cl)cc3Cl)n[nH]c2=S)cc1
Answer: c. COc1ccc(/C=C/C(=O)Nc2cc(C(F)(F)F)ccc2Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(/C=C/C(=O)Nc2cc(C(F)(F)F)ccc2Cl)cc1
COc1ccc(/C=C/C(=O)Nc2cc(C(F)(F)F)ccc2Cl)cc1
(E)-N-[2-chloro-5-(trifluoromethyl)phenyl]-3-(4-methoxyphenyl)prop-2-enamide