Problem statement: Answer the MCQ question.
Query: Which drug has a -2.681\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. CC(=O)c1ccc(OCc2cc(C(=O)NC(C)c3cnn(C)c3)no2)cc1
b. CC(C)Cc1nc(NCCN2CCOCC2)c(C#N)c2c1COC(C)(C)C2
c. O=C(NN1C(=O)CSC1=S)C(=O)NN1C(=O)CSC1=S
d. COc1ccc(C2=NN(C(=O)CSc3nnnn3C)C(c3ccco3)C2)cc1
Answer: b. CC(C)Cc1nc(NCCN2CCOCC2)c(C#N)c2c1COC(C)(C)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)Cc1nc(NCCN2CCOCC2)c(C#N)c2c1COC(C)(C)C2
CC(C)Cc1nc(NCCN2CCOCC2)c(C#N)c2c1COC(C)(C)C2
3,3-dimethyl-8-(2-methylpropyl)-6-(2-morpholin-4-ylethylamino)-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile