Problem statement: Answer the MCQ question.
Query: Which compound has a -5.000\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COC(=O)c1ccc(NC(=S)NC2c3ccccc3CC2O)cc1
b. Cc1ccc(NC(=O)NC(=O)c2cnccc2C(F)(F)F)c(C)c1
c. Cc1ccc(CNC(=O)CS(=O)(=O)Cc2nc(-c3ccc(C)cc3)oc2C)cc1
d. COC(=O)C1=C(c2ccc(F)cc2OCc2ccccc2)C[C@@H]2CC[C@H]1N2C(=O)N1CCOCC1
e. COc1ccc(CCNC(=O)CSc2ccc3nnc(CCNC(=O)c4ccccc4)n3n2)cc1OC
Answer: b. Cc1ccc(NC(=O)NC(=O)c2cnccc2C(F)(F)F)c(C)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(NC(=O)NC(=O)c2cnccc2C(F)(F)F)c(C)c1
Cc1ccc(NC(=O)NC(=O)c2cnccc2C(F)(F)F)c(C)c1
N-[(2,4-dimethylphenyl)carbamoyl]-4-(trifluoromethyl)pyridine-3-carboxamide