Problem statement: Answer the MCQ question.
Question: Which drug has a -0.624\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1cccc(CNC(=S)Nc2cc(C)cc(C)c2)c1
b.) COCCCNCCCOc1ccc(C)cc1Br.O=C(O)C(=O)O
c.) CCCn1c2c(c(O)c(C(=O)NCCCN(CC)CC)c1=O)CCCC2.Cl
d.) CSc1n[nH]c(-c2sccc2OCc2ccc(C)cc2)n1
e.) CCOC(=O)C(NC(=O)CC(C)C)(Nc1cc(C)on1)C(F)(F)F
Answer: e. CCOC(=O)C(NC(=O)CC(C)C)(Nc1cc(C)on1)C(F)(F)F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C(NC(=O)CC(C)C)(Nc1cc(C)on1)C(F)(F)F
CCOC(=O)C(NC(=O)CC(C)C)(Nc1cc(C)on1)C(F)(F)F
ethyl 3,3,3-trifluoro-2-(3-methylbutanoylamino)-2-[(5-methyl-1,2-oxazol-3-yl)amino]propanoate