Problem statement: Answer the MCQ question.
Question: Which compound has a 15.889\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1cccc(CCNC(=O)CCS(=O)(=O)c2ccc3nc(C)sc3c2)c1
b. C=CCc1cccc(C=Nc2ccc(Br)cc2)c1O
c. O=c1ccc2cc(S(=O)(=O)N3CCN(c4ccc(Cl)cc4)CC3)ccc2o1
d. CCOC(=O)c1c(/N=C/N(C)C)sc(/C=N/Nc2ccccc2)c1-c1ccc(Cl)cc1
e. Cc1ccc(Nc2nc(C(=O)N3CCC(C(=O)NC(C)C)CC3)cs2)cc1
Answer: d. CCOC(=O)c1c(/N=C/N(C)C)sc(/C=N/Nc2ccccc2)c1-c1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)c1c(/N=C/N(C)C)sc(/C=N/Nc2ccccc2)c1-c1ccc(Cl)cc1
CCOC(=O)c1c(/N=C/N(C)C)sc(/C=N/Nc2ccccc2)c1-c1ccc(Cl)cc1
ethyl 4-(4-chlorophenyl)-2-[(E)-dimethylaminomethylideneamino]-5-[(E)-(phenylhydrazinylidene)methyl]thiophene-3-carboxylate