Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -21.477\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CC(CNC(=O)CCC(=O)N1CCOc2ccccc21)c1ccccc1
b.) COc1cc(OC)cc(N(C(=O)CNC(=O)c2cccs2)C(C(=O)NCC2CCCO2)c2ccc(OC)c(OC)c2)c1
c.) COC(=O)c1c(-c2ccc(F)cc2)noc1N
d.) COc1ccccc1N=Cc1c(C)[nH]n(-c2ccc(C)cc2C)c1=O
e.) CN(C)CCNC(=O)C(=O)NCC1OCCN1S(=O)(=O)c1ccc2c(c1)OCCO2
Answer: c. COC(=O)c1c(-c2ccc(F)cc2)noc1N
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1c(-c2ccc(F)cc2)noc1N
COC(=O)c1c(-c2ccc(F)cc2)noc1N
methyl5-amino-3-(4-fluorophenyl)-1,2-oxazole-4-carboxylate