Task: Answer the MCQ question.
Question: Which drug exhibits a 12.658\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CC(=O)c1ccc(NC(=O)CN2CCN(S(=O)(=O)c3ccc4ccccc4c3)CC2)cc1
(b) Nn1c(Cc2cccc3ccccc23)nnc1SCCOc1ccc(Br)cc1
(c) CS(=O)(=O)c1ccc(-c2nnc(NC(=O)c3ccco3)o2)cc1
(d) COC(=O)c1ccc(CN2CCCC(C(=O)Nc3cccc(-n4cccn4)c3)C2)cc1
(e) COc1ccc(C2(c3ccc(OC)cc3)NC(=O)N(CC(=O)Nc3ccc(N4CCOCC4)cc3)C2=O)cc1
Answer: d. COC(=O)c1ccc(CN2CCCC(C(=O)Nc3cccc(-n4cccn4)c3)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(CN2CCCC(C(=O)Nc3cccc(-n4cccn4)c3)C2)cc1
COC(=O)c1ccc(CN2CCCC(C(=O)Nc3cccc(-n4cccn4)c3)C2)cc1
methyl 4-[[3-[(3-pyrazol-1-ylphenyl)carbamoyl]piperidin-1-yl]methyl]benzoate