Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 10.330\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cl.Nc1c2c(nc3ccccc13)CCCC2
b) O=C(Nc1cccc(-c2nnc(-c3ccccc3)o2)c1)C1CC1
c) CCCNC(=O)CCCN1C(=O)c2ccccc2Sc2ncccc21
d) CN(C)S(=O)(=O)c1ccc(C(=O)NCc2nnc(SCC(=O)NCc3ccco3)o2)cc1
e) Cc1cccc(NC(=O)COC(=O)c2cccs2)c1C
Answer: d. CN(C)S(=O)(=O)c1ccc(C(=O)NCc2nnc(SCC(=O)NCc3ccco3)o2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(C)S(=O)(=O)c1ccc(C(=O)NCc2nnc(SCC(=O)NCc3ccco3)o2)cc1
CN(C)S(=O)(=O)c1ccc(C(=O)NCc2nnc(SCC(=O)NCc3ccco3)o2)cc1
4-(dimethylsulfamoyl)-N-[[5-[2-(furan-2-ylmethylamino)-2-oxoethyl]sulfanyl-1,3,4-oxadiazol-2-yl]methyl]benzamide