Problem statement: Answer the multiple-choice question.
Query: Which drug has a -37.546% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) Cc1ccc(C(=O)C2=C(O)C(=O)N(Cc3ccco3)C2c2cccc(Br)c2)o1
(b) Cc1c(Br)c(C(F)(F)F)nn1CC(=O)NCCCn1ccnc1
(c) O=C(NCC[C@@H]1C[C@@H]2C=C[C@H]1C2)c1cc(COc2ccc(F)cc2F)on1
(d) CCCn1c(=O)c2c(ncn2C)n(CCC)c1=O
(e) COc1cc(NC(=S)NC(=O)c2ccc(C(C)(C)C)cc2)ccc1NC(=O)c1cccs1
Answer: b. Cc1c(Br)c(C(F)(F)F)nn1CC(=O)NCCCn1ccnc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1c(Br)c(C(F)(F)F)nn1CC(=O)NCCCn1ccnc1
Cc1c(Br)c(C(F)(F)F)nn1CC(=O)NCCCn1ccnc1
2-[4-bromo-5-methyl-3-(trifluoromethyl)pyrazol-1-yl]-N-(3-imidazol-1-ylpropyl)acetamide