Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -20.519% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1cc2c(cc1NC(=O)CSc1nnnn1-c1ccccc1)oc1ccccc12
b) Cc1ccc(Cn2c(CN3CC(C)OC(C)C3)nc3c2c(=O)[nH]c(=O)n3C)cc1
c) Oc1ccc(/C=N/Nc2ccnc3cc(Cl)ccc23)cc1O
d) COc1cc(CNC2CCCC2)cc(Br)c1OCC(=O)Nc1ccccc1C
e) Cc1ccn2cc(-c3ccc(O)c(O)c3)nc2c1.Cl
Answer: b. Cc1ccc(Cn2c(CN3CC(C)OC(C)C3)nc3c2c(=O)[nH]c(=O)n3C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(Cn2c(CN3CC(C)OC(C)C3)nc3c2c(=O)[nH]c(=O)n3C)cc1
Cc1ccc(Cn2c(CN3CC(C)OC(C)C3)nc3c2c(=O)[nH]c(=O)n3C)cc1
8-[(2,6-dimethylmorpholin-4-yl)methyl]-3-methyl-7-[(4-methylphenyl)methyl]purine-2,6-dione