Problem statement: Answer the MCQ question.
Query: Which compound exhibits a 3.766% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. c1ccc2c(c1)OCC(c1nn3c(Cn4nnc5ccccc54)nnc3s1)O2
b. COc1cc2c(cc1OC)CN(CC(=O)Nc1ccc3c(c1)OCO3)CC2
c. COc1ccc(OCC(O)Cn2cnc(-c3ccc(Br)cc3)c2)cc1
d. CCOc1ccc2nc(N3C(=O)CNC3=S)sc2c1
e. O=S(=O)(NCc1cc(-c2ccccc2Cl)no1)c1ccc(Cl)cc1
Answer: b. COc1cc2c(cc1OC)CN(CC(=O)Nc1ccc3c(c1)OCO3)CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)CN(CC(=O)Nc1ccc3c(c1)OCO3)CC2
COc1cc2c(cc1OC)CN(CC(=O)Nc1ccc3c(c1)OCO3)CC2
N-(1,3-benzodioxol-5-yl)-2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)acetamide