Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -42.773% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Cc1ccc(OCCCCN2CCc3ccccc3C2)cc1.Cl
b c1ccc2c(c1)OCC(c1nnc3sc(-c4cnccn4)nn13)O2
c CSCC[C@H](NC(=O)N1CCn2c1nc1ccccc12)C(=O)NCc1ccco1
d COCCn1nnnc1CN(CCc1ccc(OC)c(OC)c1)Cc1cc2ccc(C)cc2[nH]c1=O
e COc1cccc(/C=C/C(=O)OCC(=O)Nc2cccc(S(=O)(=O)N(C)C)c2)c1
Answer: d. COCCn1nnnc1CN(CCc1ccc(OC)c(OC)c1)Cc1cc2ccc(C)cc2[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCn1nnnc1CN(CCc1ccc(OC)c(OC)c1)Cc1cc2ccc(C)cc2[nH]c1=O
COCCn1nnnc1CN(CCc1ccc(OC)c(OC)c1)Cc1cc2ccc(C)cc2[nH]c1=O
3-[[2-(3,4-dimethoxyphenyl)ethyl-[[1-(2-methoxyethyl)tetrazol-5-yl]methyl]amino]methyl]-7-methyl-1H-quinolin-2-one