Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -2.745% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCc1c(-c2ccccc2)nc2nc(C)c(C)nn12
b) COc1ccc(-c2c(C(F)(F)F)oc3c(CN4CCN(C)CC4)c(O)ccc3c2=O)cc1
c) COc1cc(/C=C/c2cc(OC(C)=O)c3ccccc3n2)c(OC(C)=O)c([N+](=O)[O-])c1
d) O=C1c2ccccc2C(=O)N1c1nc(-c2cccs2)cs1
e) CC(C)C(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)O
Answer: d. O=C1c2ccccc2C(=O)N1c1nc(-c2cccs2)cs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1c2ccccc2C(=O)N1c1nc(-c2cccs2)cs1
O=C1c2ccccc2C(=O)N1c1nc(-c2cccs2)cs1
2-(4-thiophen-2-yl-1,3-thiazol-2-yl)isoindole-1,3-dione