Problem statement: Answer the multiple-choice question.
Question: Which compound has a 9.222% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1cccc2c1OCC([C@@H]1C[C@H]3CN(Cc4cccc(Cl)c4)C(=O)[C@]34CCCN14)=C2
b) O=C(COC(=O)c1ccc(S(=O)(=O)N2CCCC2)cc1)Nc1ccc(F)cc1F
c) Cc1noc(C)c1C(=O)Nc1sc2c(c1C(N)=O)CCC2
d) CCCC(=O)Nc1nc2c(s1)COc1ccccc1-2
e) C=CCn1c(CNc2ccccc2)nnc1SCC(=O)N/N=C/c1ccccc1O
Answer: b. O=C(COC(=O)c1ccc(S(=O)(=O)N2CCCC2)cc1)Nc1ccc(F)cc1F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COC(=O)c1ccc(S(=O)(=O)N2CCCC2)cc1)Nc1ccc(F)cc1F
O=C(COC(=O)c1ccc(S(=O)(=O)N2CCCC2)cc1)Nc1ccc(F)cc1F
[2-(2,4-difluoroanilino)-2-oxoethyl] 4-pyrrolidin-1-ylsulfonylbenzoate