Problem statement: Answer the multiple-choice question.
Query: Which drug has a -5.943% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCOc1ccc(N2CC(C(=O)Nc3cccc(C)c3C)CC2=O)cc1
b) Cc1cc(C)cc(NC(=O)Cc2ccc(S(=O)(=O)N3CCCC3)s2)c1
c) CCOC(=O)N1CC=C2C(C#N)=C(N)C(C#N)(C#N)[C@H](c3cccs3)C2C1
d) c1ccc(CCSc2ncnc3nc[nH]c23)cc1
e) CCN(CC(=O)N1CCN(C)CC1)S(=O)(=O)c1ccc(Cl)cc1
Answer: e. CCN(CC(=O)N1CCN(C)CC1)S(=O)(=O)c1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN(CC(=O)N1CCN(C)CC1)S(=O)(=O)c1ccc(Cl)cc1
CCN(CC(=O)N1CCN(C)CC1)S(=O)(=O)c1ccc(Cl)cc1
4-chloro-N-ethyl-N-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]benzenesulfonamide