Problem statement: Answer the MCQ question.
Question: Which compound has a 18.375% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccc(/C=N/NC(=O)CNC(=O)c2ccc3c(c2)OCCO3)cc1OC
b) Br.CO[C@H]1CC=C2CCN3CCC4=C(CC(=O)OC4)[C@]23C1
c) CN(C)S(=O)(=O)c1cc(NC(=O)CSc2nn(-c3ccc(Cl)cc3)c(=S)s2)ccc1Cl
d) COc1cccc(-n2nnc3c(=O)n(Cc4cccc(C)c4)cnc32)c1
e) O=C(O)C1C2C=CC(C2)C1C(=O)NCCc1ccncc1
Answer: e. O=C(O)C1C2C=CC(C2)C1C(=O)NCCc1ccncc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(O)C1C2C=CC(C2)C1C(=O)NCCc1ccncc1
O=C(O)C1C2C=CC(C2)C1C(=O)NCCc1ccncc1
3-(2-pyridin-4-ylethylcarbamoyl)bicyclo[2.2.1]hept-5-ene-2-carboxylicacid