Problem statement: Answer the multiple-choice question.
Query: Which compound has a -4.789% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCOC(=O)N1CCN(C(=O)c2ccc(Cl)nc2)CC1
(b) COc1ccc2c(c1)C1(Nc3ccccc3-c3nc4ccccc4n31)C(=O)N2
(c) CCN(CC(=O)Nc1ccccc1C(F)(F)F)C(=O)CCc1c(C)[nH]c(=O)c(C#N)c1C
(d) COC(=O)C1=NN(c2cccc(C)c2)C2C(=O)N(c3ccccc3OC)C(=O)C12
(e) CC(C)[C@H](NC(=O)C1CCN(S(=O)(=O)c2ccccc2)CC1)C(=O)NCc1ccccn1
Answer: d. COC(=O)C1=NN(c2cccc(C)c2)C2C(=O)N(c3ccccc3OC)C(=O)C12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=NN(c2cccc(C)c2)C2C(=O)N(c3ccccc3OC)C(=O)C12
COC(=O)C1=NN(c2cccc(C)c2)C2C(=O)N(c3ccccc3OC)C(=O)C12
methyl 5-(2-methoxyphenyl)-1-(3-methylphenyl)-4,6-dioxo-3a,6a-dihydropyrrolo[3,4-c]pyrazole-3-carboxylate