Task: Answer the MCQ question.
Question: Which drug has a 16.144% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCc1nnc(NC(=O)c2cc(S(=O)(=O)N3CCCCC3)ccc2N2CCOCC2)s1
(b) CC1(C)C(C=C(Cl)Cl)C1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1
(c) O=C(CSc1nnc(CNc2ccccc2)o1)N1CCCc2ccccc21
(d) CCOC(=O)c1c(C)[nH]c(O)c1C=Nc1ccccc1
(e) O=C(N/N=C/c1cccc2ccccc12)c1cccc(F)c1
Answer: b. CC1(C)C(C=C(Cl)Cl)C1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1(C)C(C=C(Cl)Cl)C1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1
CC1(C)C(C=C(Cl)Cl)C1C(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1
3-(2,2-dichloroethenyl)-2,2-dimethyl-N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]cyclopropane-1-carboxamide