Problem statement: Answer the MCQ question.
Query: Which drug has a -6.348% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) c1ccc(N2CCN(c3nnc(Cc4cccnc4)c4ccccc34)CC2)nc1
b) CCOC(=O)C(CC)Sc1nc2c(c(=O)[nH]c(=O)n2C)n1CCc1ccccc1
c) CCN(CC(=O)Nc1c(F)cccc1F)C(=O)C1=COCCO1
d) CN(C(=O)CN1CCC(NC(=O)c2ccccc2Br)CC1)C1CCCCC1
e) COC(=O)c1ccc(CSc2nc3ccccc3c(=O)n2-c2ccccc2)o1
Answer: c. CCN(CC(=O)Nc1c(F)cccc1F)C(=O)C1=COCCO1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN(CC(=O)Nc1c(F)cccc1F)C(=O)C1=COCCO1
CCN(CC(=O)Nc1c(F)cccc1F)C(=O)C1=COCCO1
N-[2-(2,6-difluoroanilino)-2-oxoethyl]-N-ethyl-2,3-dihydro-1,4-dioxine-5-carboxamide