Task: Answer the multiple choice question.
Question: Which drug exhibits a 5.375% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a) CCOC(=O)c1sc(-c2ccccc2)cc1NC(=O)c1ccc(S(=O)(=O)N(CCOC)CCOC)cc1
b) COc1ccc(CNC(=O)[C@@H]2CC=C[C@@H]3CCN(Cc4ccccc4)C(=O)[C@@H]32)cc1
c) Cc1ccc(NC(=O)c2ccc(NS(=O)(=O)/C=C/c3ccccc3)cc2)nc1
d) CCOC(=O)C1CCN(S(=O)(=O)c2cc(C(=O)OC)n(C)c2)CC1
Answer: b. COc1ccc(CNC(=O)[C@@H]2CC=C[C@@H]3CCN(Cc4ccccc4)C(=O)[C@@H]32)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)[C@@H]2CC=C[C@@H]3CCN(Cc4ccccc4)C(=O)[C@@H]32)cc1
COc1ccc(CNC(=O)[C@@H]2CC=C[C@@H]3CCN(Cc4ccccc4)C(=O)[C@@H]32)cc1
(4aS,8R,8aS)-2-benzyl-N-[(4-methoxyphenyl)methyl]-1-oxo-3,4,4a,7,8,8a-hexahydroisoquinoline-8-carboxamide