Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -26.461% hERG inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1cccc(N(C(=O)CNC(=O)c2ccco2)C(C(=O)NC2CCCC2)c2cccnc2)c1C
b) COC(=O)CSc1nc(N)c(NC(=O)c2ccc(OC)c(OC)c2)c(=O)[nH]1
c) COc1ccc(CNC(=O)COC(=O)CCN2C(=O)C3CC=CCC3C2=O)cc1OC
d) CN(C)/C=C(\C=O)c1ncc(C(F)(F)F)cc1Cl
e) COCCCNC(=O)CN(CCc1ccccc1)S(=O)(=O)c1ccc(OC)cc1
Answer: e. COCCCNC(=O)CN(CCc1ccccc1)S(=O)(=O)c1ccc(OC)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCCNC(=O)CN(CCc1ccccc1)S(=O)(=O)c1ccc(OC)cc1
COCCCNC(=O)CN(CCc1ccccc1)S(=O)(=O)c1ccc(OC)cc1
2-[(4-methoxyphenyl)sulfonyl-(2-phenylethyl)amino]-N-(3-methoxypropyl)acetamide