Problem statement: Answer the MCQ question.
Question: Which drug has a -24.318% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCOC(=O)c1cc(CC)sc1N1C(=O)CC(Sc2ncccc2C(=O)O)C1=O
(b) COc1cc(/C=N/n2cnnc2)ccc1Oc1nc(Cl)ncc1F
(c) Cc1nn(-c2ccccc2)c(C)c1NC(=O)COC(=O)/C=C/c1ccccc1
(d) COC(=O)CCC(=O)OC1(C)C(=O)C2=CN(C(CO)CO)C(c3ccc(OC)cc3)=CC2=C(Br)C1=O
(e) COc1cc(OC)cc(-c2cc(N)n(S(=O)(=O)c3cccc4nsnc34)n2)c1
Answer: b. COc1cc(/C=N/n2cnnc2)ccc1Oc1nc(Cl)ncc1F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(/C=N/n2cnnc2)ccc1Oc1nc(Cl)ncc1F
COc1cc(/C=N/n2cnnc2)ccc1Oc1nc(Cl)ncc1F
(E)-1-[4-(2-chloro-5-fluoropyrimidin-4-yl)oxy-3-methoxyphenyl]-N-(1,2,4-triazol-4-yl)methanimine