Problem statement: Answer the multiple-choice question.
Query: Which compound has a -41.274% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) S=C(Nc1ccc(Br)cc1)N1CCN(C2CCCCC2)CC1
b) CNC(=O)c1ccc(Nc2nnc(-c3ccc(C)c(S(N)(=O)=O)c3)c3ccccc23)cc1
c) COc1ccc(-c2noc(C3CCCN(C(=O)Nc4ccccc4)C3)n2)cc1
d) CC1CCN(C(=O)CSc2nnc(CNc3ccc(F)cc3)n2Cc2ccco2)CC1
e) Cc1ccc(-n2nc3c(=O)n(C(C)C(=O)NCc4ccco4)nc(C)c3c2C)cc1
Answer: e. Cc1ccc(-n2nc3c(=O)n(C(C)C(=O)NCc4ccco4)nc(C)c3c2C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(-n2nc3c(=O)n(C(C)C(=O)NCc4ccco4)nc(C)c3c2C)cc1
Cc1ccc(-n2nc3c(=O)n(C(C)C(=O)NCc4ccco4)nc(C)c3c2C)cc1
2-[3,4-dimethyl-2-(4-methylphenyl)-7-oxopyrazolo[3,4-d]pyridazin-6-yl]-N-(furan-2-ylmethyl)propanamide