Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -54.609% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] CC1(C)SC(=S)N(NC(=O)Nc2cccc3ccccc23)C1N(O)C(=O)Nc1ccccc1
[b] N#CCCN(C(=O)COC(=O)C1=NNC(=O)CC1)c1ccccc1
[c] O=C(CN1CCCCC1)N1CCCc2c1c(=O)oc1ccc(OCc3ccccc3)cc21
[d] O=C(CSc1nnc(-c2ccccn2)o1)Nc1ccc(F)cc1
Answer: c. O=C(CN1CCCCC1)N1CCCc2c1c(=O)oc1ccc(OCc3ccccc3)cc21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CN1CCCCC1)N1CCCc2c1c(=O)oc1ccc(OCc3ccccc3)cc21
O=C(CN1CCCCC1)N1CCCc2c1c(=O)oc1ccc(OCc3ccccc3)cc21
9-phenylmethoxy-4-(2-piperidin-1-ylacetyl)-2,3-dihydro-1H-chromeno[3,4-b]pyridin-5-one