Problem statement: Answer the MCQ question.
Query: Which drug has a -28.816% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a) CN(C(=O)c1cncc(Br)c1)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O
b) O=S(=O)(c1ccc2nc(SCc3cccc(Cl)c3)[nH]c2c1)N1CCOCC1
c) O=c1[nH]c(=S)[nH]c(O)c1C(c1ccccn1)c1c(O)[nH]c(=S)[nH]c1=O
d) CCOC(=O)C[C@H]1c2ccc(C(F)(F)F)cc2S(=O)(=O)N1Cc1ccccc1
Answer: d. CCOC(=O)C[C@H]1c2ccc(C(F)(F)F)cc2S(=O)(=O)N1Cc1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C[C@H]1c2ccc(C(F)(F)F)cc2S(=O)(=O)N1Cc1ccccc1
CCOC(=O)C[C@H]1c2ccc(C(F)(F)F)cc2S(=O)(=O)N1Cc1ccccc1
ethyl 2-[(3S)-2-benzyl-1,1-dioxo-6-(trifluoromethyl)-3H-1,2-benzothiazol-3-yl]acetate