Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -35.839% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=c1[nH]nc(SCc2cc(Cl)ccc2Cl)c(=O)[nH]1
(b) COCCC(=O)N1CCc2c([nH]c3ccccc23)C1C(C)(C)C
(c) COc1cc(C(=O)OCC(=O)N2c3ccccc3NC(=O)C2(C)C)ccc1OCC(C)C
(d) COC(=O)CCC(=O)N1CCCC(N2CCN(c3cccc(C(F)(F)F)c3)CC2)C1
(e) O=C(C1CCC1)N1CCN(c2ccc(Cl)cc2)CC1
Answer: d. COC(=O)CCC(=O)N1CCCC(N2CCN(c3cccc(C(F)(F)F)c3)CC2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)CCC(=O)N1CCCC(N2CCN(c3cccc(C(F)(F)F)c3)CC2)C1
COC(=O)CCC(=O)N1CCCC(N2CCN(c3cccc(C(F)(F)F)c3)CC2)C1
methyl4-oxo-4-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]piperidin-1-yl]butanoate