Problem statement: Answer the multiple choice question.
Question: Which drug has a -22.375% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) Clc1ccc(-c2[nH]ncc2-n2cncn2)cc1
b.) COc1ccc(-c2c3c(=O)n(C)c(=O)n(C)c3cn2N2CCOCC2)cc1
c.) CCN(C(=O)COC(=O)c1ccc(F)c(S(=O)(=O)N2CCOCC2)c1)C1CCS(=O)(=O)C1
d.) COc1ccccc1N1CCN(Cc2cc(=O)c(OCC(=O)NC3CCCC3)co2)CC1
e.) COc1cc(OC)cc(C(=O)Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)c1
Answer: c. CCN(C(=O)COC(=O)c1ccc(F)c(S(=O)(=O)N2CCOCC2)c1)C1CCS(=O)(=O)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN(C(=O)COC(=O)c1ccc(F)c(S(=O)(=O)N2CCOCC2)c1)C1CCS(=O)(=O)C1
CCN(C(=O)COC(=O)c1ccc(F)c(S(=O)(=O)N2CCOCC2)c1)C1CCS(=O)(=O)C1
[2-[(1,1-dioxothiolan-3-yl)-ethylamino]-2-oxoethyl]4-fluoro-5-morpholin-4-ylsulfonylbenzoate