Problem statement: Answer the MCQ question.
Query: Which compound has a 4.242% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) N#Cc1ccc(S(=O)(=O)N2CCN(Cc3cccs3)CC2)cc1
(b) Cn1c(=O)n(C)c2cc(NS(=O)(=O)c3ccc(Cl)s3)ccc21
(c) CC1(C(=O)NNC(=O)c2ccc(=O)oc2)CC1Br
(d) C[C@@H]1NS(=O)(=O)[C@H]2C[C@@H]3C=C[C@]2(O3)[C@H]1OC(=O)c1ccccc1Br
(e) COc1ccc(-c2nn(Cc3ccccc3)cc2C(=O)NC2CC2)cc1OC
Answer: d. C[C@@H]1NS(=O)(=O)[C@H]2C[C@@H]3C=C[C@]2(O3)[C@H]1OC(=O)c1ccccc1Br
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C[C@@H]1NS(=O)(=O)[C@H]2C[C@@H]3C=C[C@]2(O3)[C@H]1OC(=O)c1ccccc1Br
C[C@@H]1NS(=O)(=O)[C@H]2C[C@@H]3C=C[C@]2(O3)[C@H]1OC(=O)c1ccccc1Br
[(1S,2S,3S,6S,8R)-3-methyl-5,5-dioxo-11-oxa-5λ6-thia-4-azatricyclo[6.2.1.01,6]undec-9-en-2-yl] 2-bromobenzoate