Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -27.683% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CN(C(=O)CSc1nc2ccc(Br)cc2c(=O)n1Cc1ccco1)C1CCS(=O)(=O)C1
b: COC(=O)c1ccc(NS(=O)(=O)c2ccc3c(c2)oc(=O)n3C)cc1
c: COc1cc2c(cc1OC)-c1cc(Nc3ccccc3Br)nc(=O)n1CC2
d: CCCCN(C)C(=O)c1cc2cc3cc(OC)ccc3nc2o1
e: COc1ccc(C(CNC(=O)C(=O)NC2CCCCC2)N2CCN(C)CC2)cc1
Answer: e. COc1ccc(C(CNC(=O)C(=O)NC2CCCCC2)N2CCN(C)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(CNC(=O)C(=O)NC2CCCCC2)N2CCN(C)CC2)cc1
COc1ccc(C(CNC(=O)C(=O)NC2CCCCC2)N2CCN(C)CC2)cc1
N'-cyclohexyl-N-[2-(4-methoxyphenyl)-2-(4-methylpiperazin-1-yl)ethyl]oxamide