Problem statement: Answer the MCQ question.
Question: Which compound has a -23.198% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Cc1cc2c(C)nc3ccccc3c2o1
b COCCNC(=O)/C(C#N)=C/C=C/c1ccccc1
c O=C(NCc1ccccc1)C(c1ccc(F)cc1)N(Cc1ccc2c(c1)OCO2)C(=O)Cn1nnc(-c2cccs2)n1
d CC(=O)NCC(=O)N1CCCC(C(=O)c2ccc(Oc3ccccc3)cc2)C1
e Cc1ccc(C(C(=O)NC2CCCCC2)N(Cc2cccnc2)C(=O)c2csnn2)cc1
Answer: d. CC(=O)NCC(=O)N1CCCC(C(=O)c2ccc(Oc3ccccc3)cc2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(=O)NCC(=O)N1CCCC(C(=O)c2ccc(Oc3ccccc3)cc2)C1
CC(=O)NCC(=O)N1CCCC(C(=O)c2ccc(Oc3ccccc3)cc2)C1
N-[2-oxo-2-[3-(4-phenoxybenzoyl)piperidin-1-yl]ethyl]acetamide