Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -13.958% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C(COc1ccccc1Cl)Nc1ccccc1C(=O)N1CCCCC1
b.) COc1ccc(C(=O)Nc2nnc(C)s2)cc1S(=O)(=O)N1CCOCC1
c.) COc1ccc(NC(=O)c2nnn(CC(=O)Nc3ccccc3OC)c2N)c(OC)c1
d.) CC(=O)Oc1ccccc1C(=O)Nc1ccccc1C(=O)N1CCCCC1
e.) COc1cccc(-c2cc(C(F)(F)F)n3nc(N)nc3n2)c1
Answer: b. COc1ccc(C(=O)Nc2nnc(C)s2)cc1S(=O)(=O)N1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)Nc2nnc(C)s2)cc1S(=O)(=O)N1CCOCC1
COc1ccc(C(=O)Nc2nnc(C)s2)cc1S(=O)(=O)N1CCOCC1
4-methoxy-N-(5-methyl-1,3,4-thiadiazol-2-yl)-3-morpholin-4-ylsulfonylbenzamide