Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 15.128% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
[a] COC(=O)c1c(C)oc(C)c1S(=O)(=O)NC(C)(C)C
[b] O=S(=O)(c1ccc(F)cc1)N1CC2CCCN2c2ccc(C(F)(F)F)cc21
[c] COc1ccc(NC2CCCN(C(=O)CCC(=O)c3ccc(F)cc3)C2)cc1
[d] CCC(C)n1c(-c2ccco2)nc2nc3ccccc3nc21
Answer: b. O=S(=O)(c1ccc(F)cc1)N1CC2CCCN2c2ccc(C(F)(F)F)cc21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=S(=O)(c1ccc(F)cc1)N1CC2CCCN2c2ccc(C(F)(F)F)cc21
O=S(=O)(c1ccc(F)cc1)N1CC2CCCN2c2ccc(C(F)(F)F)cc21
5-(4-fluorophenyl)sulfonyl-7-(trifluoromethyl)-2,3,3a,4-tetrahydro-1H-pyrrolo[1,2-a]quinoxaline