Task: Answer the multiple-choice question.
Query: Which compound exhibits a -1.429% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a COc1ccc(-n2nc(C(=O)NCC(=O)N3CCC4(CC3)OCCO4)c3ccccc3c2=O)cc1
b COc1ccc(NC(=O)CN2c3cccc4cccc(c34)S2(=O)=O)cc1
c COc1cc2c(cc1OC)C(C)N(S(=O)(=O)c1cnc(Cl)c(Cl)c1)CC2
d O=C(Nc1ccc(N2CCCC2)c(Cl)c1)c1cccs1
Answer: c. COc1cc2c(cc1OC)C(C)N(S(=O)(=O)c1cnc(Cl)c(Cl)c1)CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(C)N(S(=O)(=O)c1cnc(Cl)c(Cl)c1)CC2
COc1cc2c(cc1OC)C(C)N(S(=O)(=O)c1cnc(Cl)c(Cl)c1)CC2
2-(5,6-dichloropyridin-3-yl)sulfonyl-6,7-dimethoxy-1-methyl-3,4-dihydro-1H-isoquinoline