Problem statement: Answer the multiple choice question.
Question: Which drug has a -13.616% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1ccc(Cn2cc([N+](=O)[O-])nc2C)cc1[N+](=O)[O-]
[b] O=S(=O)(c1ccccc1)N1CCN(C(=S)NCc2ccccc2)CC1
[c] COc1ccc(C2C(C(=O)c3cccs3)=C(O)C(=O)N2c2cccc(C)n2)cc1
[d] COCCCNC(=S)N1CCCN(c2nc3cc(C)ccc3cc2C#N)CC1
[e] CC(C)NC(=O)NC(=O)COC(=O)c1ccc(S(=O)(=O)NCc2ccco2)cc1
Answer: d. COCCCNC(=S)N1CCCN(c2nc3cc(C)ccc3cc2C#N)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCCNC(=S)N1CCCN(c2nc3cc(C)ccc3cc2C#N)CC1
COCCCNC(=S)N1CCCN(c2nc3cc(C)ccc3cc2C#N)CC1
4-(3-cyano-7-methylquinolin-2-yl)-N-(3-methoxypropyl)-1,4-diazepane-1-carbothioamide