Problem statement: Answer the MCQ question.
Query: Which drug has a -58.256% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CCOC(=O)CSC1=C(C#N)C(c2sccc2C)CC(=O)N1
b.) O=C(c1ccc(Cl)cc1)N1CCN(c2cc(=O)[nH]nc2-c2ccccc2)CC1
c.) CC(OC(=O)CCCSc1nc2ccccc2s1)C(=O)NC(N)=O
d.) C[C@@H]1CC=C[C@H]2[C@H]1C(=O)N(Cc1ccccc1)[C@H]2c1ccoc1
e.) CC(NC(=O)Cc1cccc2ccccc12)C(=O)N1CCC(=O)CC1
Answer: b. O=C(c1ccc(Cl)cc1)N1CCN(c2cc(=O)[nH]nc2-c2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccc(Cl)cc1)N1CCN(c2cc(=O)[nH]nc2-c2ccccc2)CC1
O=C(c1ccc(Cl)cc1)N1CCN(c2cc(=O)[nH]nc2-c2ccccc2)CC1
4-[4-(4-chlorobenzoyl)piperazin-1-yl]-3-phenyl-1H-pyridazin-6-one