Task: Answer the multiple-choice question.
Query: Which compound has a -36.374% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1cc(CNCCO)cc(Br)c1OCc1cccs1.Cl
b CCN(C(=O)c1cnc(NC(C)C)cc1C(F)(F)F)c1ccc(Cl)cc1
c Cc1nc(CS(=O)c2ccc(Cl)cc2)cc(N2CCOCC2)n1
d O=C1c2ccccc2C2(c3cc(C(F)(F)F)cc(C(F)(F)F)c3)NCCN12
e CC(O)c1ccc(OCCN(C)c2ccccn2)cc1
Answer: b. CCN(C(=O)c1cnc(NC(C)C)cc1C(F)(F)F)c1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN(C(=O)c1cnc(NC(C)C)cc1C(F)(F)F)c1ccc(Cl)cc1
CCN(C(=O)c1cnc(NC(C)C)cc1C(F)(F)F)c1ccc(Cl)cc1
N-(4-chlorophenyl)-N-ethyl-6-(propan-2-ylamino)-4-(trifluoromethyl)pyridine-3-carboxamide