Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -21.448% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C(Nc1ccccn1)C1CCCN1S(=O)(=O)c1ccc(Cl)cc1
b. COC(=O)c1c(NC(=O)C2CC=CCC2C(=O)O)sc(C(N)=O)c1C
c. O=C(Nc1ccc(-c2ccc([N+](=O)[O-])cc2)cc1)c1ccccc1F
d. CC(C)(C)CN1CCNC(=O)C1CC(=O)N1CCC(C(=O)N2CCOCC2)CC1
e. COCc1ccc(C(=O)N2CCCC(CCC(=O)NCc3ccccc3F)C2)o1
Answer: a. O=C(Nc1ccccn1)C1CCCN1S(=O)(=O)c1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1ccccn1)C1CCCN1S(=O)(=O)c1ccc(Cl)cc1
O=C(Nc1ccccn1)C1CCCN1S(=O)(=O)c1ccc(Cl)cc1
1-(4-chlorophenyl)sulfonyl-N-pyridin-2-ylpyrrolidine-2-carboxamide