Problem statement: Answer the multiple choice question.
Query: Which drug has a -2.124% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCC(=NCc1ccccc1)C1=C(O)C(C(=O)OC)C(C)(C)CC1=O
b) COc1ccccc1N(C)S(=O)(=O)c1ccc(Cl)c(C(=O)NCC2(N(C)C)CCCCC2)c1
c) Cc1cc(C)n(CC(=O)N/N=C/c2ccco2)n1
d) O=C(COC(=O)/C=C/c1ccc(OC(F)F)cc1)Nc1ccc(S(=O)(=O)N2CCCC2)cc1
e) CC1C(=O)Nc2ccccc2N1C(=O)c1ccc(Cl)c(Cl)c1
Answer: d. O=C(COC(=O)/C=C/c1ccc(OC(F)F)cc1)Nc1ccc(S(=O)(=O)N2CCCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COC(=O)/C=C/c1ccc(OC(F)F)cc1)Nc1ccc(S(=O)(=O)N2CCCC2)cc1
O=C(COC(=O)/C=C/c1ccc(OC(F)F)cc1)Nc1ccc(S(=O)(=O)N2CCCC2)cc1
[2-oxo-2-(4-pyrrolidin-1-ylsulfonylanilino)ethyl] (E)-3-[4-(difluoromethoxy)phenyl]prop-2-enoate