Problem statement: Answer the multiple-choice question.
Question: Which compound has a -85.713% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] Cc1ccc(S(=O)(=O)N(C)Cc2nc(-c3ccc(Br)cc3)no2)cc1
[b] Cc1cccc(NC(=O)C(C)N2C(=O)C3C4CC(C(Br)C4Br)C3C2=O)c1
[c] O=C(O)CN1CCN(Cc2ccc(F)cc2Cl)C1=O
[d] Clc1ccc2nc(-c3ccc(Cl)nc3)[nH]c2c1
[e] O=C(c1ccc2c(c1)OCO2)C1CCCN(Cc2ccc(OC(F)F)cc2)C1
Answer: e. O=C(c1ccc2c(c1)OCO2)C1CCCN(Cc2ccc(OC(F)F)cc2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccc2c(c1)OCO2)C1CCCN(Cc2ccc(OC(F)F)cc2)C1
O=C(c1ccc2c(c1)OCO2)C1CCCN(Cc2ccc(OC(F)F)cc2)C1
1,3-benzodioxol-5-yl-[1-[[4-(difluoromethoxy)phenyl]methyl]piperidin-3-yl]methanone