Problem statement: Answer the MCQ question.
Question: Which compound has a -17.698% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) Cc1ccccc1S(=O)(=O)Cc1ccc(C(=O)N2CCN(c3ccccc3F)CC2)o1
b.) C=CCNC(=O)C12CCC(C)(C(=O)[C@H]1Br)C2(C)C
c.) OCC1(CCOc2ccccc2)CCN(Cc2ccc3cccc(F)c3n2)CC1
d.) CCC1=C(OC(=O)N(CC)CC)N2C(=O)OC(=NCC3CC3)[C@]2(Cc2ccccc2)[C@H]2C1=CC[C@H]1C(=O)N(C)C(=O)[C@H]12
Answer: d. CCC1=C(OC(=O)N(CC)CC)N2C(=O)OC(=NCC3CC3)[C@]2(Cc2ccccc2)[C@H]2C1=CC[C@H]1C(=O)N(C)C(=O)[C@H]12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCC1=C(OC(=O)N(CC)CC)N2C(=O)OC(=NCC3CC3)[C@]2(Cc2ccccc2)[C@H]2C1=CC[C@H]1C(=O)N(C)C(=O)[C@H]12
CCC1=C(OC(=O)N(CC)CC)N2C(=O)OC(=NCC3CC3)[C@]2(Cc2ccccc2)[C@H]2C1=CC[C@H]1C(=O)N(C)C(=O)[C@H]12
[(1R,2S,12R,16S)-2-benzyl-3-(cyclopropylmethylimino)-8-ethyl-14-methyl-5,13,15-trioxo-4-oxa-6,14-diazatetracyclo[7.7.0.02,6.012,16]hexadeca-7,9-dien-7-yl] N,N-diethylcarbamate