Task: Answer the multiple choice question.
Query: Which drug exhibits a -22.809% hERG inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCOC(=O)[C@H]1[C@H]2COc3ccc(C)cc3[C@@H]2N2C(=O)c3ccc(F)cc3NC(=O)[C@@]12C
(b) Cc1ccccc1OCC(=O)NCCCNC(=O)c1ccco1
(c) COc1nc(NCc2ccco2)nc(NC2CCCCC2)n1
(d) Cn1cc(CN2CCC(CO)CC2)c(-c2ccc(Oc3ccccc3)cc2)n1
(e) COc1ccc(-c2c(C(=O)O)c(-c3ccccc3)cn2C)cc1
Answer: a. CCOC(=O)[C@H]1[C@H]2COc3ccc(C)cc3[C@@H]2N2C(=O)c3ccc(F)cc3NC(=O)[C@@]12C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)[C@H]1[C@H]2COc3ccc(C)cc3[C@@H]2N2C(=O)c3ccc(F)cc3NC(=O)[C@@]12C
CCOC(=O)[C@H]1[C@H]2COc3ccc(C)cc3[C@@H]2N2C(=O)c3ccc(F)cc3NC(=O)[C@@]12C
ethyl(2R,11R,12S,13R)-18-fluoro-5,13-dimethyl-14,22-dioxo-9-oxa-1,15-diazapentacyclo[11.9.0.02,11.03,8.016,21]docosa-3(8),4,6,16(21),17,19-hexaene-12-carboxylate