Problem statement: Answer the MCQ question.
Query: Which drug has a -1.751% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCN(CC)CCNC(=S)Nc1ccc2nc(N3CCN(C)CC3)cc(C)c2c1
(b) CCOC(=O)C1=C(CP(=O)(c2ccccc2)c2ccccc2)NC(=O)NC1c1ccc(OC)cc1
(c) COc1cccc(N2CCN(C3C4CC5CC(C4)CC3C5)CC2)c1
(d) O=C(/C=C/NNC(=O)c1ccccc1)c1ccc([N+](=O)[O-])cc1
(e) Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3cccc(N4C(=O)CCC4=O)c3)cc2)n1
Answer: e. Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3cccc(N4C(=O)CCC4=O)c3)cc2)n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3cccc(N4C(=O)CCC4=O)c3)cc2)n1
Cc1cc(C)nc(NS(=O)(=O)c2ccc(NC(=O)c3cccc(N4C(=O)CCC4=O)c3)cc2)n1
N-[4-[(4,6-dimethylpyrimidin-2-yl)sulfamoyl]phenyl]-3-(2,5-dioxopyrrolidin-1-yl)benzamide