Task: Answer the MCQ question.
Query: Which drug exhibits a -6.226% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C(O)CN1C(=O)NC2(CCOc3ccccc32)C1=O
b) CCOC(=O)[C@H]1[C@H]2COc3ccc(Cl)cc3[C@@H]2N2C(=O)CN(Cc3ccco3)C(=O)[C@@]12C
c) CC(=O)c1ccccc1C(=O)N(C)C1CCCN(Cc2ccccc2F)C1
d) CCOc1ccc(N(CC(=O)NCc2ccc3c(c2)OCO3)C(=O)c2csnn2)cc1
e) Cn1c(=O)n(CCOc2ccccc2Cl)c2ccccc21
Answer: b. CCOC(=O)[C@H]1[C@H]2COc3ccc(Cl)cc3[C@@H]2N2C(=O)CN(Cc3ccco3)C(=O)[C@@]12C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)[C@H]1[C@H]2COc3ccc(Cl)cc3[C@@H]2N2C(=O)CN(Cc3ccco3)C(=O)[C@@]12C
CCOC(=O)[C@H]1[C@H]2COc3ccc(Cl)cc3[C@@H]2N2C(=O)CN(Cc3ccco3)C(=O)[C@@]12C
ethyl(1R,10R,11S,12R)-4-chloro-14-(furan-2-ylmethyl)-12-methyl-13,16-dioxo-8-oxa-14,17-diazatetracyclo[8.7.0.02,7.012,17]heptadeca-2(7),3,5-triene-11-carboxylate