Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -2.377% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCOCCCn1c(SCC(=O)NC(C)(C)C)nc2ccccc2c1=O
b) CCOc1ccc(-n2nnnc2SCC(=O)Nc2ccc(NC(C)=O)cc2)cc1
c) COCCNC(=S)N1CCN(c2nc(-c3cccc(OC)c3)cs2)CC1
d) CCOC(=O)CCc1c(C)c2ccc(OC3CCCCC3=O)c(C)c2oc1=O
e) Cn1c(=O)c(C(=O)COC(=O)c2cc(C3CC3)nc3ccccc23)c(N)n(Cc2ccccc2)c1=O
Answer: d. CCOC(=O)CCc1c(C)c2ccc(OC3CCCCC3=O)c(C)c2oc1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)CCc1c(C)c2ccc(OC3CCCCC3=O)c(C)c2oc1=O
CCOC(=O)CCc1c(C)c2ccc(OC3CCCCC3=O)c(C)c2oc1=O
ethyl 3-[4,8-dimethyl-2-oxo-7-(2-oxocyclohexyl)oxychromen-3-yl]propanoate