Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -12.903% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CCc1c2c(nc3ccc(OC(=O)N4CCC(N5CCCCC5)CC4)cc13)-c1cc3c(c(=O)n1C2)COC(=O)[C@]3(O)CC.Cl.O
b. COc1ccc(C(=O)CC(SCC(NC(C)=O)C(=O)O)c2ccc(Cl)cc2)cc1OC
c. O=C(c1cccc(Cl)c1)N1CCN(c2ccccn2)CC1
d. COc1ccc(N2CCN(c3ncccc3C#N)CC2)cc1
e. CCCNC(=O)c1cccc(NC(=O)C(C)C)c1
Answer: c. O=C(c1cccc(Cl)c1)N1CCN(c2ccccn2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1cccc(Cl)c1)N1CCN(c2ccccn2)CC1
O=C(c1cccc(Cl)c1)N1CCN(c2ccccn2)CC1
(3-chlorophenyl)-(4-pyridin-2-ylpiperazin-1-yl)methanone