Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -12.536% hERG inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1ccc(CCNC(=O)CNC(=O)c2ccc(Br)o2)cc1OC
[b] Cc1ccccc1C(=O)NC(CC(C)C)C(=O)N1CCN(c2ccccc2)CC1
[c] CCOC(=O)[C@@H]1[C@H]2COc3ccccc3[C@H]2N2C(=O)N(c3cccc(F)c3)C(=O)[C@]12C
[d] CC1CC(=O)c2cnc(NCC3CCCO3)nc2C1
[e] Cc1cccc(OCCNc2cc(N3CCN(C)CC3)ccc2[N+](=O)[O-])c1
Answer: c. CCOC(=O)[C@@H]1[C@H]2COc3ccccc3[C@H]2N2C(=O)N(c3cccc(F)c3)C(=O)[C@]12C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)[C@@H]1[C@H]2COc3ccccc3[C@H]2N2C(=O)N(c3cccc(F)c3)C(=O)[C@]12C
CCOC(=O)[C@@H]1[C@H]2COc3ccccc3[C@H]2N2C(=O)N(c3cccc(F)c3)C(=O)[C@]12C
ethyl(1S,10R,11R,12S)-14-(3-fluorophenyl)-12-methyl-13,15-dioxo-8-oxa-14,16-diazatetracyclo[8.6.0.02,7.012,16]hexadeca-2,4,6-triene-11-carboxylate