Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 10.957% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1cc(-c2n[nH]c(=S)n2-c2ccc(Br)cc2)cc(OC)c1OC
b O=C(Cc1ccc(S(=O)(=O)N2CCOCC2)s1)NCCc1ccc(F)cc1
c COc1cc(-c2nc3cccc(C)n3c2NCC2CCCO2)ccc1O
d CC12CN(Cc3ccccc3)CC(C)(CN(Cc3ccccc3)C1)C2=O
e C[C@@H](NC(=O)c1nc[nH]c1C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)c1ccccc1
Answer: d. CC12CN(Cc3ccccc3)CC(C)(CN(Cc3ccccc3)C1)C2=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC12CN(Cc3ccccc3)CC(C)(CN(Cc3ccccc3)C1)C2=O
CC12CN(Cc3ccccc3)CC(C)(CN(Cc3ccccc3)C1)C2=O
3,7-dibenzyl-1,5-dimethyl-3,7-diazabicyclo[3.3.1]nonan-9-one