Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -23.675% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] Cc1nc2ccccc2cc1C(=O)N(C)Cc1ccccc1
[b] CCC1=C(OC(=O)N(CC)CC)N2C(=O)OC(=NCC(=O)OC)[C@]2(Cc2ccccc2)[C@H]2C1=CC[C@H]1C(=O)N(c3ccccc3)C(=O)[C@H]12
[c] CC(C)c1ccc(CC(C)C2C3=C(CCCC3=O)OC3=C2C(=O)CCC3)cc1
[d] CCOC(=O)N1CCC(N(CCN(C)C)C(=S)Nc2ccccc2OC)CC1
[e] CCNS(=O)(=O)c1ccc(NC(=O)Nc2ccccc2OC)cc1
Answer: b. CCC1=C(OC(=O)N(CC)CC)N2C(=O)OC(=NCC(=O)OC)[C@]2(Cc2ccccc2)[C@H]2C1=CC[C@H]1C(=O)N(c3ccccc3)C(=O)[C@H]12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCC1=C(OC(=O)N(CC)CC)N2C(=O)OC(=NCC(=O)OC)[C@]2(Cc2ccccc2)[C@H]2C1=CC[C@H]1C(=O)N(c3ccccc3)C(=O)[C@H]12
CCC1=C(OC(=O)N(CC)CC)N2C(=O)OC(=NCC(=O)OC)[C@]2(Cc2ccccc2)[C@H]2C1=CC[C@H]1C(=O)N(c3ccccc3)C(=O)[C@H]12
methyl 2-[[(1R,2S,12R,16S)-2-benzyl-7-(diethylcarbamoyloxy)-8-ethyl-5,13,15-trioxo-14-phenyl-4-oxa-6,14-diazatetracyclo[7.7.0.02,6.012,16]hexadeca-7,9-dien-3-ylidene]amino]acetate