Problem statement: Answer the multiple choice question.
Question: Which drug has a -72.449% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COc1ccc(CCNC(=O)CSCc2ccc([N+](=O)[O-])cc2)cc1OC
b.) CCOC(=O)[C@H]1[C@H]2COc3ccc(Cl)cc3[C@@H]2N2C(=O)CNC(=O)[C@@]12C
c.) O=C(c1ccco1)N1CCN(S(=O)(=O)N2CCOCC2)CC1
d.) N=c1c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1
e.) N#CCCN(C1CCCCC1)S(=O)(=O)CCOc1ccccc1
Answer: d. N=c1c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N=c1c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1
N=c1c(C(=O)NCc2cccnc2)cc2c(=O)n3ccccc3nc2n1CC1CCCO1
6-imino-2-oxo-7-(oxolan-2-ylmethyl)-N-(pyridin-3-ylmethyl)-1,7,9-triazatricyclo[8.4.0.03,8]tetradeca-3(8),4,9,11,13-pentaene-5-carboxamide