Problem statement: Answer the MCQ question.
Question: Which drug has a -16.006% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCOC(=O)Cn1nc(C)cc1NC(=O)c1cc(OC)c(OC)c(OC)c1
b) C/C(=N\NC(=O)NC1CCCCC1)C1CCCCC1
c) Cl.Clc1cccc(-c2ccc(CNCCCN3CCOCC3)o2)c1
d) Cc1ccc(N=Cc2cc(C)n(C3CCCC3)c2C)cc1
e) COc1cc(OC)c2ccc(=O)oc2c1C(CCN1CCCCC1)c1ccc(N(C)C)cc1
Answer: e. COc1cc(OC)c2ccc(=O)oc2c1C(CCN1CCCCC1)c1ccc(N(C)C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(OC)c2ccc(=O)oc2c1C(CCN1CCCCC1)c1ccc(N(C)C)cc1
COc1cc(OC)c2ccc(=O)oc2c1C(CCN1CCCCC1)c1ccc(N(C)C)cc1
8-[1-[4-(dimethylamino)phenyl]-3-piperidin-1-ylpropyl]-5,7-dimethoxychromen-2-one