Task: Answer the multiple-choice question.
Query: Which drug exhibits a -0.749% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COCCNc1nnc(SCC(=O)c2ccc3c(c2)OCO3)s1
b. COc1ccc(CN2C(=O)C(CC(C)C)Nc3ncnc(N4CCOCC4)c32)cc1.O=C(O)C(F)(F)F
c. O=C(Nc1ccnc(-c2cccnc2)n1)c1cccs1
d. COc1cc(C(=S)N2CCOCC2)cc(OC)c1OC(=O)c1ccc(F)cc1
e. CCCCCCSc1ccc([C@H]2N[C@@](CC(C)C)(C(=O)OC)[C@H]3C(=O)N(C)C(=O)[C@@H]23)cc1OC.O=C(O)C(F)(F)F
Answer: b. COc1ccc(CN2C(=O)C(CC(C)C)Nc3ncnc(N4CCOCC4)c32)cc1.O=C(O)C(F)(F)F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CN2C(=O)C(CC(C)C)Nc3ncnc(N4CCOCC4)c32)cc1.O=C(O)C(F)(F)F
COc1ccc(CN2C(=O)C(CC(C)C)Nc3ncnc(N4CCOCC4)c32)cc1.O=C(O)C(F)(F)F
5-[(4-methoxyphenyl)methyl]-7-(2-methylpropyl)-4-morpholin-4-yl-7,8-dihydropteridin-6-one;2,2,2-trifluoroacetic acid