Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -27.451% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
[a] N#CC1=C(N)Oc2n[nH]c(-c3ccncc3)c2C1c1ccsc1
[b] Cc1ccccc1NC(=O)CSc1nc2ccccc2c2nc(CCn3cncc3C)nn12
[c] COc1ccc(NC(=O)COC(=O)[C@@H]2CCCN2C(=O)c2cccs2)c(OC)c1
[d] CN(C(=O)c1ccc(NC(=O)Cc2ccc(NC(=O)C3CCN(C(=O)c4ccccc4)CC3)cc2)cc1)C1CC1
Answer: c. COc1ccc(NC(=O)COC(=O)[C@@H]2CCCN2C(=O)c2cccs2)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)COC(=O)[C@@H]2CCCN2C(=O)c2cccs2)c(OC)c1
COc1ccc(NC(=O)COC(=O)[C@@H]2CCCN2C(=O)c2cccs2)c(OC)c1
[2-(2,4-dimethoxyanilino)-2-oxoethyl] (2S)-1-(thiophene-2-carbonyl)pyrrolidine-2-carboxylate