Problem statement: Answer the MCQ question.
Question: Which drug has a -45.378% human ether-à-go-go related gene (hERG) inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) Cc1cccc(NCC(=O)N/N=C\c2cccn2C)c1
b.) O=C(Nc1ccnn1C1CCN(Cc2ccccc2F)CC1)C1CCCC1
c.) COC(=O)[C@H](Cc1ccccc1)NC(=O)O[C@@H]1C(=O)c2cc(Br)ccc2O[C@H]1c1cccc(OC)c1
d.) Cc1cc(C=O)c(C)n1-c1ccc(N2CCCC2)c([N+](=O)[O-])c1
e.) Cc1ccc(C(=O)OCC(=O)N(CC(C)C)c2c(N)n(Cc3ccccc3)c(=O)[nH]c2=O)o1
Answer: b. O=C(Nc1ccnn1C1CCN(Cc2ccccc2F)CC1)C1CCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1ccnn1C1CCN(Cc2ccccc2F)CC1)C1CCCC1
O=C(Nc1ccnn1C1CCN(Cc2ccccc2F)CC1)C1CCCC1
N-[2-[1-[(2-fluorophenyl)methyl]piperidin-4-yl]pyrazol-3-yl]cyclopentanecarboxamide