Problem statement: Answer the MCQ question.
Query: Which drug has a -7.927% hERG inhibition at a concentration of 10uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a. COCCCN(C(=O)Nc1cccc(Cl)c1)C(C)c1ccccn1
b. Cl.Nc1nc(N2CCN(C/C=C/c3ccccc3)CC2)nc2ccccc12
c. COC(=O)C1=C(c2cccc(OCc3ccccc3)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCCOC(C)C
Answer: c. COC(=O)C1=C(c2cccc(OCc3ccccc3)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCCOC(C)C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2cccc(OCc3ccccc3)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCCOC(C)C
COC(=O)C1=C(c2cccc(OCc3ccccc3)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCCOC(C)C
methyl (1R,5S)-3-(3-phenylmethoxyphenyl)-8-(3-propan-2-yloxypropylcarbamoyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate