Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -30.980% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccc(C(CNCC(=O)Nc2ccccc2F)N(C)C)cc1.O=C(O)C(=O)O
(b) COc1ccc2c(c1)[N+](C)(C)C(C)(C)C=C2C.[I-]
(c) C/C(=N\Nc1ccc(Cl)c(C(=O)O)c1)c1ccc[nH]1
(d) C=CCn1c(=O)c(C(=O)NCc2ccc3c(c2)OCO3)c(O)c2ccccc21
(e) O=C(COc1ccccc1)N1CCN(S(=O)(=O)c2cccs2)CC1
Answer: e. O=C(COc1ccccc1)N1CCN(S(=O)(=O)c2cccs2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COc1ccccc1)N1CCN(S(=O)(=O)c2cccs2)CC1
O=C(COc1ccccc1)N1CCN(S(=O)(=O)c2cccs2)CC1
2-phenoxy-1-(4-thiophen-2-ylsulfonylpiperazin-1-yl)ethanone