Problem statement: Answer the multiple-choice question.
Question: Which compound has a -74.907% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a) COc1cccc(CCN2CCC(CNS(=O)(=O)c3cc(-c4cc(C)no4)ccc3OC)CC2)c1
b) CC(=O)C1=C(C)N(CC2CC2)C(=O)N[C@H]1c1ccccc1
c) CN(C)S(=O)(=O)N(CC(=O)N1CCN(Cc2ccccc2)CC1)c1ccccc1
d) Brc1ccc(C2=Nc3ccccc3C(c3ccncc3)=NN2)cc1
Answer: a. COc1cccc(CCN2CCC(CNS(=O)(=O)c3cc(-c4cc(C)no4)ccc3OC)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CCN2CCC(CNS(=O)(=O)c3cc(-c4cc(C)no4)ccc3OC)CC2)c1
COc1cccc(CCN2CCC(CNS(=O)(=O)c3cc(-c4cc(C)no4)ccc3OC)CC2)c1
2-methoxy-N-[[1-[2-(3-methoxyphenyl)ethyl]piperidin-4-yl]methyl]-5-(3-methyl-1,2-oxazol-5-yl)benzenesulfonamide