Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -8.425% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=C(COc1ccccc1)N1CCN(CCN2C(=O)c3cccc4cccc(c34)C2=O)CC1
(b) CCCS(=O)(=O)N1CCC(C(=O)NCCN(CC)c2ccccc2)CC1
(c) Cc1ccccc1NS(=O)(=O)c1cc(S(C)(=O)=O)ccc1C
(d) CC(C)N(C(=O)CSc1ccc(S(=O)(=O)N2CCCCC2)cn1)c1ccccc1
(e) CCOC(=O)C1(CCOC)CCN(Cc2cccc(OCc3ccccc3)c2)CC1
Answer: a. O=C(COc1ccccc1)N1CCN(CCN2C(=O)c3cccc4cccc(c34)C2=O)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COc1ccccc1)N1CCN(CCN2C(=O)c3cccc4cccc(c34)C2=O)CC1
O=C(COc1ccccc1)N1CCN(CCN2C(=O)c3cccc4cccc(c34)C2=O)CC1
2-[2-[4-(2-phenoxyacetyl)piperazin-1-yl]ethyl]benzo[de]isoquinoline-1,3-dione