Problem statement: Answer the multiple choice question.
Question: Which compound exhibits a -27.335% human ether-à-go-go related gene (hERG) inhibition at 10uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) Cc1c(-n2cc(C(=O)O)c(=O)c3cc(F)c(N4CCCC(O)C4)c(F)c32)c(=O)n(-c2ccccc2)n1C
b.) N#CC1=C(N)N(c2ccc(Br)cc2)C2=C(C(=O)CCC2)C1c1cccnc1
c.) COC(=O)c1ccc(NC(=O)CN2CCN(CC#N)CC2)cc1.O=C(O)C(=O)O
d.) Cc1ccc(N(CC(=O)NC2CCCCCC2)S(=O)(=O)c2c(C)nn(C)c2C)cc1
Answer: b. N#CC1=C(N)N(c2ccc(Br)cc2)C2=C(C(=O)CCC2)C1c1cccnc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_10uM#}{herg_central_at_10uM__units} {herg_central_at_10uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_10uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N#CC1=C(N)N(c2ccc(Br)cc2)C2=C(C(=O)CCC2)C1c1cccnc1
N#CC1=C(N)N(c2ccc(Br)cc2)C2=C(C(=O)CCC2)C1c1cccnc1
2-amino-1-(4-bromophenyl)-5-oxo-4-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carbonitrile